Background Bicuspid aortic stenosis accounts for almost 50% of patients undergoing surgical aortic valve replacement in the younger patients. Expanding the indication of transcatheter aortic valve replacement (TAVR) toward lower-risk and younger populations will lead to increased use of TAVR for patients with bicuspid aortic valve (BAV) stenosis despite the exclusion of bicuspid anatomy in all…
JACC: CardioOncology Editor-in-chief, Bo nnie Ky, MD, MSCE, FACC and David Austin, MD, FRCP discuss PROACT, a phase three randomized open label blinded endpoint superiority…
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AbstractPatients with paradoxical low-flow low-gradient aortic stenosis pose a diagnostic challenge when it comes to assessing the severity of aortic stenosis (AS) noninvasively. We describe…
JACC stands at the forefront of disseminating cutting-edge research, reviews, and clinical guidance, seeking to advance global cardiovascular health. We are seeking two creative, innovative…
JACC: Case Reports is inviting submissions of challenging rheumatic heart disease (RHD) cases highlighting the global burden of cardiovascular disease for a forthcoming special issue…
AbstractBackgroundIschemia with no obstructive coronary arteries is frequently caused by coronary microvascular dysfunction (CMD). Consensus diagnostic criteria for CMD include baseline angiographi…
Drs Zaid, Wessly, and Hatab have contributed equally to this work. Drs Zaid, Wessly, and Hatab have contributed equally to this work. Drs Zaid, Wessly,…
AbstractBackgroundGenetic variants in titin (TTN) are associated with dilated cardiomyopathy (DCM) and skeletal myopathy. However, the skeletal muscle phenotype in individuals carrying heterozygous…
A long-standing expert roundtable discussion hosted by JACC Editor-in-Chief Valentin Fuster, MD, PhD, MACC, ACC Cardiology Hour provides key takeaways on top clinical trials released…
AbstractBackgroundNon-pulmonary vein (PV) triggers are increasingly targeted during atrial fibrillation (AF) ablation. P-wave morphology (PWM) can be useful because point mapping of AF triggers is…
