Characteristics of breast ducts in normal risk and high risk women and their relationship to ductal cytologic atypia.

Breast ductal cytologic atypia is an important risk factor for sporadic breast cancer. Characterization of the associated normal breast tissue is needed to develop additional methods of risk assessment and new targets for breast cancer prevention. We conducted a prospective clinical trial evaluating women at normal risk (NR) or at high-risk (HR) for sporadic breast cancer. Breast ductal cells…

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