Multiple subpopulations of synovial tissue macrophages with varied transcriptional, phenotypic and functional features may contribute to disease flare and tissue repair in patients with active rheumatoid arthritis and patients in clinical remission.
Nature Reviews Rheumatology – Multidimensional and single-cell profiling of peripheral blood and inflamed tissues is a powerful and high-resolution tool for the stratification of patients…
Nature Reviews Rheumatology – Multidimensional and single-cell profiling of peripheral blood and inflamed tissues is a powerful and high-resolution tool for the stratification of patients…
Nature Reviews Rheumatology – Early identification of osteoarthritis (OA) prior to the development of symptoms is challenging. Post-traumatic OA provides a model for the development…
Nature Reviews Rheumatology – This Review discusses joint-specific memory (the tendency of arthritis to recur in previously inflamed joints), explores the involvement of resident memory…
Nature Reviews Rheumatology – In a head-to-head phase III trial of two drugs that target IL-5 or its receptor, benralizumab was noninferior to mepolizumab for…
Nature Reviews Rheumatology – Author Correction: Therapeutic potential in rheumatic diseases of extracellular vesicles derived from mesenchymal stromal cells
Nature Reviews Rheumatology – Author Correction: Proposals for the rheumatological use of JAK inhibitors
Nature Reviews Rheumatology – Despite the transformative potential of treatments for systemic autoinflammatory diseases, these conditions remain underfunded and understudied. Urgent, coordinated…
Nature Reviews Rheumatology – Immunoengineering involves the design of materials with specific properties relating to the immune system. In this Review the authors consider the…
Worldwide, it is estimated that one in five men over the age of 50 years will experience an osteoporotic fracture in their remaining lifetime, and…
