Cellular states capable of promoting tumor progression and resisting therapies exist in heterogeneous tumors. Marjanovic et al. discover that a high-plasticity cell state common to mouse and human lung tumors drives cellular heterogeneity, and is highly tumorigenic and drug resistant, as well as associates with poor patient prognosis.
Join the HJF Team! HJF is seeking a Nurse Practitioner I to support the Murtha Cancer Center Research Program’s (MCCRP) Center for Prostate Disease…
Nature Methods – We developed Significant Latent Factor Interaction Discovery and Exploration (SLIDE), an interpretable machine learning approach that can infer hidden states (latent factors)…
One of Australia’s greatest biomedical research scientists was honored today by giving the Ashley Dunn Oration at the Lorne Cancer conference – Professor…
Shiao et al. reveals the phenotypic and spatial changes that occur in the tumor immune microenvironment following anti-PD-1 therapy and radiation in triple-negative breast cancer. They…
Shiao et al. reveals the phenotypic and spatial changes that occur in the tumor immune microenvironment following anti-PD-1 therapy and radiation in triple-negative breast cancer. They…
A move from one sector to another isn’t a one-way street. Researchers who have pivoted between the two explain why.
Cancer research and treatment priorities for 2024: NCI’s new director talks to cancer community
Dr. Filipe De Carvahlo is a urologic oncologist at Brigham and Women’s Hospital, and he has a huge reason to be excited about cancer research…
A unified interface to spatial transcriptomics deconvolution tools – GitHub – omnideconv/spacedeconv: A unified interface to spatial transcriptomics deconvolution tools
Spatial transcriptomic profiling of cancer has enabled spatial delineation of malignant transcriptional heterogeneity, intercellular communication, and organization of microanatomical structures within the tumor microenvironment. This…
