Recent outbreaks of Ebola virus (EBOV) and SARS-CoV-2 have exposed our limited therapeutic options and poor understanding of cellular mechanisms that block viral infections. Using a transposon-mediated gene-activation screen in human cells, we identify that the MHC class II transactivator (CIITA) has antiviral activity against EBOV. CIITA induces resistance by activating expression of the p41…
Blocking lipid synthesis induces DNA damage in prostate cancer and increases cell death caused by PARP inhibition.
A key mentor ’helped me see that engaging with the people around me would improve my state of mind,“ this researcher writes
Bold action is needed to address unmanageable time scales, limited access to information, and a need to build capacity
On this week’s show: Researchers are testing HIV drugs and monoclonal antibodies against long-lasting COVID-19, and what it takes to turn a symbiotic friend into…
Findings reveal the marine mammals have a sense of team membership
A transcription factor implicated in bacterial immunity inhibits host responses during influenza virus infection.
Ultrahigh–power-density multilayer ceramic capacitors (MLCCs) are critical components in electrical and electronic systems. However, the realization of a high energy density combined with a high…
Epoxy resin thermosets (ERTs) are an important class of polymeric materials. However, owing to their highly cross-linked nature, they suffer from poor recyclability, which contributes…
The US National Center for Science and Engineering Statistics (NCSES) regularly conducts national surveys of the US-based PhD- and college-educated populations. These surveys monitor who…
A small-molecule inhibitor of the ClC-1 chloride channel improves skeletal muscle function in rat models and patients with myasthenia gravis.
