Proteins are manufactured by ribosomes—macromolecular complexes of protein and RNA molecules that are assembled within major nuclear compartments called nucleoli1,2. Existing models suggest that RNA polymerases I and III (Pol I and Pol III) are the only enzymes that directly mediate the expression of the ribosomal RNA (rRNA) components of ribosomes. Here we show, however, that RNA polymerase II…
Nature Communications – Brazil has operated a conditional cash transfer program to support families living in precarious conditions since 2004. Here, the authors use linked…
Nature Medicine – Recent developments in bioengineering and organic chemistry have enabled targeting of the previously ‘undruggable’ KRAS; this review summarizes the successes,…
Nature – Countries are cracking down on tobacco use and vaping — the laws could save thousands of lives and billions of dollars, say scientists.
Nature – Human genetic evidence increases the success rate of drugs from clinical development to approval but we are still far from reaching peak genetic…
Nature Methods – This Review provides an overview of bioinformatic approaches that enable immune repertoire analyses at the single-cell level.
Nature – Algorithm examines images of metastatic cells to identify the location of the primary tumour.
Nature Reviews Neuroscience – Pathological compulsive behaviour is a potential transdiagnostic symptom of several neuropsychiatric disorders. In this Review, Robbins et al. examine the…
Nature Biotechnology – Gamification of the multiple sequence alignment problem improves microbial phylogeny estimates.
npj Science of Learning – Investigating lexical categorization in reading based on joint diagnostic and training approaches for language learners
