Analyses of epigenomic datasets spanning transitions from normal prostate epithelium to localized prostate cancer to metastases show that latent developmental programs are reactivated in metastatic disease and that prostate lineage-specific regulatory elements are strongly enriched for prostate cancer risk heritability.
Nature Reviews Clinical Oncology – In these Evidence-Based Guidelines, a multidisciplinary panel of experts from the European Hematology Association and the European Myeloma Network provide…
Nature Reviews Clinical Oncology – In these Evidence-Based Guidelines, a multidisciplinary panel of experts from the European Hematology Association and the European Myeloma Network provide…
Nature Reviews Clinical Oncology – Zanidatamab shows promise as first-line therapy for advanced-stage HER2+ GEA
Nature Reviews Clinical Oncology – Second-line tarlatamab improves OS in SCLC
Nature Reviews Clinical Oncology – Robot-assisted laparoscopic surgery confers improved oncological outcomes
Nature Reviews Clinical Oncology – Adding durvalumab to perioperative FLOT improves gastric cancer outcomes
Nature Reviews Clinical Oncology – Immune-checkpoint inhibitors (ICIs) have improved lung cancer outcomes, although resistance to these agents presents a substantial challenge. This Review…
Nature Reviews Clinical Oncology – Liquid biopsy-based tests have demonstrated potential as a minimally invasive and broadly applicable approach to simultaneously screen individuals for multiple…
Nature Reviews Clinical Oncology – Adding lurbinectedin to maintenance therapy improves outcomes in ES-SCLC
Nature Reviews Clinical Oncology – Adding lurbinectedin to maintenance therapy improves outcomes in ES-SCLC
