During the last decade, moderate progress in the treatment of pancreatic ductal adenocarcinoma (PDAC) has been realized with updated chemotherapeutic regimens, advanced operative techniques, and in some cases, targeted genetic-based therapy. Treating patients with borderline resectable or locally…
People with increased polygenic risk scores for higher body mass index (BMI) would need to walk about 2300 more steps each day to have the…
This cohort study assesses whether use of medications to control blood pressure in patients who have undergone endovascular thrombectomy for acute ischemic stroke is associated…
This JAMA Internal Medicine Clinical Insights review provides an update on the current recommendations for resistant hypertension management.
This cross-sectional study evaluates associations between vision impairment and psychosocial outcomes in US adults.
This randomized clinical trial compares the efficacy, safety, and tolerability of daily oral minoxidil, 5 mg, with twice-daily topical minoxidil, 5%, for 24 weeks in…
This nationwide cohort study with sibling control analysis examines the association of acetaminophen use during pregnancy with children’s risk of autism, ADHD, and intellectual disability.
This randomized clinical trial assesses the safety and effectiveness of plozasiran, an investigational APOC3-targeted drug, in the reduction of serum triglyceride level in patients with…
This cohort study examines the risk of a second primary breast cancer in women who were aged 40 years or younger when first diagnosed with…
This cross-sectional study assesses the ability of a large language model to process medical data and display clinical reasoning compared with the ability of attending…
This case report describes a 17-year-old boy with reduced consciousness and T2-weighted hyperintensity, focal diffusion restriction, and microhemorrhages within the deep gray nuclei and surrounding…
