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Mashup Score: 0Self-reported Metabolic Risk Factor Associations with Adenomatous, Sessile Serrated, and Synchronous Adenomatous and Sessile Serrated Polyps - 2 year(s) ago
Studies have found a positive association between metabolic risk factors, such as obesity and diabetes, and adenomatous polyps (AP). However, fewer studies have assessed the association between sessile serrated polyps (SSP) or synchronous diagnosis of APs and SSPs (synch polyps). Study participants ( N = 1,370; ages 40–85) undergoing screening colonoscopy were enrolled between August 2016 and…
Source: Cancer Prevention ResearchCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
Identification of high-risk population among hepatitis B virus (HBV)/hepatitis C virus (HCV)-infected individuals with first-degree relatives (FDR) who have liver cancer is important to implement precise intervention. A cross-sectional study was conducted under the framework of a population-based Cancer Screening Program in Urban China (CanSPUC), aimed to develop and validate a simple noninvasive…
Source: Cancer Prevention ResearchCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
From the February issue and in recognition of #CancerPreventionMonth: Risk of liver cirrhosis in HBV/HCV-infected individuals with first-degree relatives who have liver cancer: development and validation of a simple model by Liu et al. https://t.co/8zYqEyi10p https://t.co/ewEWZPeHFU
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Mashup Score: 0Germline Cancer Susceptibility Gene Testing in Unselected Patients with Hepatobiliary Cancers: A Multi-Center Prospective Study - 2 year(s) ago
Data from germline testing in unselected patients with hepatobiliary cancers are limited. Identification of germline predisposition can have important implications on cancer treatment and family counseling. To determine prevalence of pathogenic germline variants (PGV) in patients with hepatobiliary cancer, we undertook a prospective multi-site study of germline sequencing using a >80-gene…
Source: Cancer Prevention ResearchCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
From the February issue and in recognition of #CancerPreventionMonth: Germline Cancer Susceptibility Gene Testing in Unselected Patients with Hepatobiliary Cancers: A Multi-Center Prospective Study by Pedro LS Uson Junior, N. Jewel Samadder and colleagues. https://t.co/G72EP6CZqe https://t.co/N6zYS0H4z6
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Mashup Score: 0The Costs and Benefits of Risk Stratification for Colorectal Cancer Screening Based On Phenotypic and Genetic Risk: A Health Economic Analysis - 2 year(s) ago
Population-based screening for colorectal cancer is an effective and cost-effective way of reducing colorectal cancer incidence and mortality. Many genetic and phenotypic risk factors for colorectal cancer have been identified, leading to development of colorectal cancer risk scores with varying discrimination. However, these are not currently used by population screening programs. We performed…
Source: Cancer Prevention ResearchCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
#ICYMI: The Costs and Benefits of Risk Stratification for Colorectal Cancer Screening Based On Phenotypic and Genetic Risk: A Health Economic Analysis by Chloe Thomas, @JulietU_S, and colleagues @ScHARRSheffield. https://t.co/3jCtBmejdQ https://t.co/fcGwGLzmVD
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Mashup Score: 1Progestin Significantly Inhibits Carcinogenesis in the Mogp-TAg Transgenic Mouse Model of Fallopian Tube Cancer - 2 year(s) ago
Recent studies suggest that the fallopian tube epithelium (FTE) harbors the precursor for high-grade ovarian cancer, creating opportunities for targeting the FTE for ovarian cancer prevention. Preclinical evidence supports progestins as ovarian cancer preventives, but the effect of progestins on the FTE is not well characterized. The murine oviduct–specific glycoprotein promotor-driven simian…
Source: Cancer Prevention ResearchCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
From the February issue and in recognition of #CancerPreventionMonth: A Randomized Double-blind Placebo-controlled Trial of Oral Aspirin for Protection of Melanocytic Nevi Against UV-induced DNA Damage; @huntsmancancer, @UofUHealth. https://t.co/jBA1C20c8E https://t.co/U00ckhQkMM
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Mashup Score: 0
Grape seed procyanidin extract (GSE) has been shown to exert antineoplastic properties in preclinical studies. Recently, we reported findings from a modified phase I, open-label, dose escalation clinical study conducted to evaluate the safety, tolerability, MTD, and potential chemopreventive effects of leucoselect phytosome, a standardized GSE complexed with soy phospholipids to enhance…
Source: Cancer Prevention ResearchCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
February is #CancerPreventionMonth. #ICYMI: Leucoselect Phytosome Modulates Serum Eicosapentaenoic Acid, Docosahexaenoic Acid, and Prostaglandin E3 in a Phase I Lung Cancer Chemoprevention Study by Oliver Fiehn, Jenny T. Mao and colleagues; @genomecenter. https://t.co/ZRGg5xCUMR https://t.co/CYma2t9ZQy
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Mashup Score: 2Progestin Significantly Inhibits Carcinogenesis in the Mogp-TAg Transgenic Mouse Model of Fallopian Tube Cancer - 2 year(s) ago
Recent studies suggest that the fallopian tube epithelium (FTE) harbors the precursor for high-grade ovarian cancer, creating opportunities for targeting the FTE for ovarian cancer prevention. Preclinical evidence supports progestins as ovarian cancer preventives, but the effect of progestins on the FTE is not well characterized. The murine oviduct–specific glycoprotein promotor-driven simian…
Source: Cancer Prevention ResearchCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
From the February issue and in recognition of #CancerPreventionMonth: Progestin Significantly Inhibits Carcinogenesis in the Mogp-TAg Transgenic Mouse Model of Fallopian Tube #Cancer by Omar L. Nelson, Gustavo C. Rodriguez, and colleagues. https://t.co/dFOzLYNjwl https://t.co/J4JqrzpR92
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Mashup Score: 0Cancer Prevention Research: 15 (2) - 2 year(s) ago
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Source: Cancer Prevention ResearchCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Take a look at the February issue online now! https://t.co/RaKDPkOnqA #CancerPreventionResearch https://t.co/ABw558UtHW
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Mashup Score: 0Editors' Selections from Relevant Scientific Publications - 2 year(s) ago
![][1] [ Liver Glycogen Storage in Mice (cropped from the image by Libertas Academica via Wikimedia Commons) ][2] Cancer cell metabolism transitions from conventional oxidative phosphorylation to aerobic fermentation, a process that quickly burns through available glucose. Liu et al
Source: Cancer Prevention ResearchCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Cancer Prevention Research Highlights: Read the Editors' selections from relevant scientific publications. https://t.co/PEKu79PrQZ https://t.co/vnOkEnKVRI
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Mashup Score: 3
The mechanisms underlying the regulation of a checkpoint receptor, PD-1, in tumor-infiltrating immune cells during the development of colorectal cancer (CRC) are not fully understood. Here we demonstrate that COX-2-derived PGE2, an inflammatory mediator and tumor promoter, induces PD-1 expression by enhancing NF-κB’s binding to the PD-1 promoter via an EP4-PI3K-Akt signaling pathway in both CD8+…
Source: Cancer Prevention ResearchCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
#JustPublished: The COX-2-PGE2 pathway promotes #tumor evasion in colorectal adenomas by @Rndubois, Jie Wei and colleagues. https://t.co/CmVdQGT7mB https://t.co/6m9olx0A9e
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February is #CancerPreventionMonth - #ICYMI: Self-reported Metabolic Risk Factor Associations with Adenomatous, Sessile Serrated, and Synchronous Adenomatous and Sessile Serrated Polyps by Santiago et al. https://t.co/Kkbv7PRDjr https://t.co/H9rvfo6cW8