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Mashup Score: 90Life In-Between: Bridging Innate and Adaptive Immunity | American Association of Immunologists - 11 day(s) ago
This collection features Guest Editor Sebastian Joyce and covers the complex interaction between innate and adaptive immunity.
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 21Cutting Edge: ATP13A2 Is an Endolysosomal Regulator of TLR9/7 Activation in Human Plasmacytoid Dendritic Cells - 13 day(s) ago
Key Points. Human pDCs express ATP13A2 in their endolysosomal compartments.ATP13A2-mediated polyamine transport regulates TLR9/7 activation in pDCs.ATP13A2
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
This 🚨#CuttingEdge 🚨 study reveals the role of an ATPase in regulating plasmacytoid DCs. Check it out #immunology #ReadTheJI https://t.co/uTaly6xLG4 https://t.co/l8ts2iiAIr
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Mashup Score: 7
Key Points. HD IL-2 promotes effector lymphocytes (CD8+ and NK cells) extravasation and expansion.B cells undergo oligoclonal expansion during HD IL-2 ther
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
#ICYMI 📢 This #human #clinical retrospective study evaluates patients with #RenalCellCarcinoma #cancer #metastasis treated with high-dose IL2. Read about the study & find out the impact on immune cells here #ReadTheJI: https://t.co/aARbq7Doo5 https://t.co/Ko67n8PJug
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Mashup Score: 2On the Horizon | American Association of Immunologists - 14 day(s) ago
ImmunoHorizons publishes peer-reviewed invited commentaries focused on future directions in a specific area of immunology research. Articles provide succin
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
#DYK about ImmunoHorizon’s #OnTheHorizon series? These commentaries discuss key areas of #research in #immunology & highlight current gaps in knowledge. #ReadIH to stay up-to-date: https://t.co/eFJDUcpz9G. https://t.co/D7NOOzNe8m
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Mashup Score: 0T Cell Activators Exhibit Distinct Downstream Effects on Chimeric Antigen Receptor T Cell Phenotype and Function - 15 day(s) ago
Abstract. T cell activation is an essential step in chimeric Ag receptor (CAR) T (CAR T) cell manufacturing and is accomplished by the addition of activato
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
#ICYMI Considerations for #CARTcell design are presented in this study by Underwood et al. #ReadIH to find out how cell activators used during manufacturing can impact cell function: https://t.co/ImltYHYeh7. #ImmunoHorizons https://t.co/BPu8IJ0WOm
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Mashup Score: 4Similarities in B Cell Defects between Aging and Obesity - 20 day(s) ago
Abstract. The aging population is increasing worldwide, and there is also an increase in the aging population living with overweight and obesity, due to ch
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Intrigued by the connection between obesity and aging? Dive deeper and explore "Similarities in B Cell Defects between Aging and Obesity" in The JI's Brief Reviews: https://t.co/84ly4s0vHb. #ReadTheJI #Immunology @J_Immunol https://t.co/hxUF2mHcMq
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Mashup Score: 4Similarities in B Cell Defects between Aging and Obesity - 21 day(s) ago
Abstract. The aging population is increasing worldwide, and there is also an increase in the aging population living with overweight and obesity, due to ch
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Intrigued by the connection between obesity and aging? Dive deeper and explore "Similarities in B Cell Defects between Aging and Obesity" in The JI's Brief Reviews: https://t.co/84ly4s0vHb. #ReadTheJI #Immunology @J_Immunol https://t.co/hxUF2mHcMq
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Mashup Score: 1N-Glycan Branching Regulates BTLA Opposite to PD-1 to Limit T Cell Hyperactivity Induced by Branching Deficiency - 1 month(s) ago
Key Points. N-glycan branching enhances PD-1 cell surface expression by inhibiting PD-1 endocytosis.N-glycan branching inhibits BTLA cell surface expressio
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
The impact of N-glycan branching on inhibitory receptor expression is investigated and differential effects on BTLA and PD-1 are revealed. Check out how these opposing effects act to regulate responses: https://t.co/9AzlpBVghU. #ReadTheJI #immunology https://t.co/LdcP7yecl8
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Mashup Score: 5Challenges in the Development of NK-92 Cells as an Effective Universal Off-the-Shelf Cellular Therapeutic - 1 month(s) ago
Key Points. Some cancer patients exhibit pre-existing IgM recognition of NK-92 and CAR-NK92 cells.Repeat infusions of CAR-NK92 cells to tumor patients led
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Challenges in developing off-the-shelf #immunotherapy using CAR-NK92 cells are highlighted. Learn how these cells could be optimized to improve efficacy: https://t.co/hmfnUGdo3I. #ReadTheJI #immunology https://t.co/X8Ci083yIV
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Mashup Score: 50Circulating Immune Cells from Early- and Late-onset Pre-eclampsia Displays Distinct Profiles with Differential Impact on Endothelial Activation - 1 month(s) ago
Key Points. EOPE PBMCs exhibit enhanced cell activation pathways and proinflammatory phenotypes, contributing to endothelial activation in vitro.LOPE shows
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
This study investigates maternal systemic immune responses during early and late pre-eclampsia. Discover how these responses differentially impact endothelial cell activation when compared to those during an uncomplicated pregnancy: https://t.co/GLR0fB4eEX. #ReadTheJI #immunology https://t.co/V9qF3HmJVN
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Get up-to-date on mechanisms that bridge #ImmuneSystem arms. Dr. Sebastian Joyce guest edits this special collection that highlights the complex immune circuits that impact innate & adaptive immunity. Check it out! #ReadTheJI #ICYMI #ILCs ➡️ https://t.co/o1dWOn90Am https://t.co/HbyQZGlawg