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Mashup Score: 96Advancing Genetic Testing in Kidney Diseases: Report From a National Kidney Foundation Working Group - 1 day(s) ago
About 37 million people in the United States have chronic kidney disease, a disease that encompasses diseases of multiple causes. About 10% or more of kidney diseases in adults and about 70% of selected chronic kidney diseases in children are expected to be explained by genetic causes. Despite the advances in genetic testing and an increasing understanding of the genetic bases of certain kidney diseases, genetic testing in nephrology lags behind other medical fields. More understanding of the benefits and logistics of genetic testing is needed to advance the implementation of genetic testing in chronic kidney diseases.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 9Patient, Parental, and Health Professional Perspectives on Growth in Children With CKD - 1 day(s) ago
Growth failure is a common problem among children with chronic kidney disease (CKD). Reduced height is associated with psychosocial burden, social stigma, and impaired quality of life. This study aimed to describe the aspects of growth impairment that are most impactful from the perspectives of children with CKD, their parents, and health professionals.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 4Why Symptom Burden in Non-Dialysis CKD Matters - 2 day(s) ago
Chronic kidney disease (CKD) is largely considered asymptomatic until more advanced stages of kidney dysfunction.1 Thus, research on symptom burden in CKD has mainly focused on end-stage kidney disease.2 However, accumulating evidence suggests that individuals already experience burdensome physical symptoms in early stages, long before requiring kidney replacement therapy. Burdensome symptoms affect 7 out of 10 individuals in early stages of CKD.3 Despite its prevalence, subjective symptom burden is largely under-researched in non-dialysis CKD (ND-CKD).
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 2
The Organ Procurement and Transplant Network (OPTN) Expeditious Task Force (ETF) was conceived and initiated in response to a need to move quickly to greatly expand successful deceased-donor transplant across the United States. The ETF, using data from the top 20% of transplant programs ranked by ability to manage successful growth in transplant volume, came up with a bold aim of facilitating 60,000 successful transplants by 2026 to save more lives. In order to achieve this transformational growth, the ETF will use a data-driven approach, partnering with key stakeholders across the transplant system to secure commitments, reduce barriers, obtain data, align metrics, evaluate new technologies, and run short trials that will better inform future policy developments.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 27A Young Woman With Nephrotic Syndrome: A Quiz - 2 day(s) ago
A 29-year-old Hispanic female patient with a history of rheumatic mitral stenosis, pulmonary embolism, and right upper extremity deep vein thrombosis presented to the emergency department owing to respiratory failure and bilateral large pleural effusions requiring intubation and thoracentesis. She had been previously admitted for shortness of breath and pleuritic chest pain attributed to heart failure exacerbation and transudative pleural effusions requiring thoracenteses. She resided in a trailer home and worked in a lettuce processing plant.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet-
#Quiz: A 29-yr-old female patient with rheumatic mitral stenosis, pulmonary embolism, and deep vein thrombosis presented with bilateral large pleural effusions. What is the best treatment? https://t.co/irf8EhjRQD (FREE) @n0r0zha @TWhittier_RUSH @Orhanefe_ @rahaai @SaynaNorouzi https://t.co/CfO7IIxgKT
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Mashup Score: 15
Recent evidence suggests substantial burden of symptoms experienced by people with non-dialysis chronic kidney disease (ND-CKD), but informative large-scale studies are scarce. We aimed to assess the prevalence of symptoms, and the association of overall symptom burden with quality of life in patients with moderate to severe CKD.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 88Viral Nephropathies: Core Curriculum 2024 - 3 day(s) ago
Viral-associated nephropathy is when kidney disease results from active viral replication. Because of the high global burden of viral infections, clinicians should be aware of their incidence, kidney manifestations, mechanism of injury, and management. Some viruses, such as hepatitis B, hepatitis C, human immunodeficiency virus (HIV), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can lead to nephropathy more commonly than other endemic viruses, such as Epstein-Barr virus, cytomegalovirus, and polyoma virus which are more important causes of nephropathy in the immunosuppressed patient.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 26AJKD Atlas of Renal Pathology: Subacute Bacterial Endocarditis–Associated Glomerulonephritis - 4 day(s) ago
Antibiotic therapy has decreased the incidence of glomerulonephritis related to subacute bacterial endocarditis (SBE). Kidney involvement may be the initial manifestation of SBE in about 20% of patients. Hematuria and mild proteinuria are commonly present. Hypertension and nephrotic syndrome are rare. Serum complement levels may be low. Gross hematuria may be present in patients with renal infarctions related to embolic events. The degree of GFR loss correlates with the severity of glomerulonephritis; diffuse glomerulonephritis causes moderate GFR loss, and necrotizing glomerulonephritis with crescents can cause a rapid GFR decline.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 10Sex and the Relationship Between Cardiometabolic Risk Factors and Estimated GFR Decline: A Population-Based Cohort Study - 4 day(s) ago
Females have a higher prevalence of chronic kidney disease (CKD) than males but are less likely to be treated with kidney replacement therapy (KRT). We studied the interaction between sex and the association of cardiometabolic risk factors for the decline in kidney function over time.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 24A Young Woman With Nephrotic Syndrome: A Quiz - 5 day(s) ago
A 29-year-old Hispanic female patient with a history of rheumatic mitral stenosis, pulmonary embolism, and right upper extremity deep vein thrombosis presented to the emergency department owing to respiratory failure and bilateral large pleural effusions requiring intubation and thoracentesis. She had been previously admitted for shortness of breath and pleuritic chest pain attributed to heart failure exacerbation and transudative pleural effusions requiring thoracenteses. She resided in a trailer home and worked in a lettuce processing plant.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet-
#Quiz: A 29-yr-old female patient with rheumatic mitral stenosis, pulmonary embolism, and deep vein thrombosis presented with bilateral large pleural effusions. What is the best treatment? https://t.co/irf8EhjRQD (FREE) @n0r0zha @TWhittier_RUSH @Orhanefe_ @rahaai @SaynaNorouzi https://t.co/CfO7IIxgKT
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Advancing Genetic Testing in Kidney Diseases: Report From a @nkf Working Group https://t.co/y4ADC7qdeW (FREE) @NoraFranceschi2 @alexchangmd @ndahl48 @HilaMilo @NKF_NephPros https://t.co/XbrBDkOrdx