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Mashup Score: 19
Rationale: A U-shaped relationship should exist between lung volume and pulmonary vascular resistance (PVR), with minimal PVR at FRC. Thus, positive end-expiratory pressure (PEEP) in patients with …
Source: www.atsjournals.orgCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 3Genetically Predicted Body Mass Index and Mortality in Chronic Obstructive Pulmonary Disease - 3 day(s) ago
Rationale: Body mass index (BMI) is associated with chronic obstructive pulmonary disease (COPD) mortality, but the underlying mechanisms are unclear. The effect of genetic variants aggregated into…
Source: www.atsjournals.orgCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 3Increased Pulmonary GM-CSF Causes Alveolar Macrophage Accumulation. Mechanistic Implications for Desquamative Interstitial Pneumonitis - 3 day(s) ago
Bronchopulmonary dysplasia (BPD) is characterized by impaired lung alveolar and vascular growth. We investigated the hypothesis that neonatal exposure to hyperoxia leads to persistent BPD phenotype…
Source: www.atsjournals.orgCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 8
Bronchopulmonary dysplasia (BPD) is a chronic lung disease in premature infants that results from mechanical ventilation and hyperoxia, among other factors. This disease affects approximately 15,000 prematu re infants annually in the United States. Each infant with BPD incurs a total cost of approximately $225,000 during the initial hospitalization. Infants with severe BPD often develop long-term serious morbidities, including pulmonary hypertension and neurodevelopmental impairment. This further increases
Source: www.atsjournals.orgCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 3
In March 2020, Arizona’s five extracorporeal membrane oxygenation (ECMO) programs (Banner Health, HonorHealth, Dignity Health, Mayo Clinic, and Phoenix Children’s) came together to form the Arizona ECMO (COVID-19) Workgroup (ECMO Workgroup) to discuss ECMO eligibility criteria and transfer patterns on the Arizona Surge Line, a centralized public health initiative that facilitated all intersystem transfers of patients with coronavirus disease (COVID-19) (1, 2). The Arizona Surge Line predominately processed
Source: www.atsjournals.orgCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 19Why Is Body Mass Index Related to Chronic Obstructive Pulmonary Disease? Is It All in the Genes? - 3 day(s) ago
Over 390 million individuals around the world have chronic obstructive pulmonary disease (COPD) (1). COPD accounts for more than 3.2 million deaths per year, making it the sixth leading cause of mortality worldwide (2). Although its exact pathogenesis is not known, COPD is believed to arise from a complex interplay between environmental and genetic factors over many decades, with genetics ultimately accounting for 20–40% of the variation in airflow limitation in adults and smoking behavior for up to 60%
Source: www.atsjournals.orgCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 2Increased Pulmonary GM-CSF Causes Alveolar Macrophage Accumulation. Mechanistic Implications for Desquamative Interstitial Pneumonitis - 4 day(s) ago
Lamellar bodies (LBs) are tissue-specific lysosome-related organelles in type II alveolar cells that are the main site for the synthesis, storage, and secretion of pulmonary surfactants. Defects in…
Source: www.atsjournals.orgCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 8Genetically Predicted Body Mass Index and Mortality in Chronic Obstructive Pulmonary Disease - 4 day(s) ago
Rationale: Body mass index (BMI) is associated with chronic obstructive pulmonary disease (COPD) mortality, but the underlying mechanisms are unclear. The effect of genetic variants aggregated into…
Source: www.atsjournals.orgCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 3
Background: In the United States, Black and Latino children with asthma are more likely than White children with asthma to require emergency department visits or hospitalizations because of an asth…
Source: www.atsjournals.orgCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 7The Fallacy of Electronic Cigarettes for Tobacco Dependence - 4 day(s) ago
They arrived with great promise. It does not burn, it is not tobacco, it must be better. It feels like déjà vu. We have been there before with tobacco products promoted as conferring reduced harm—but did not—from filter cigarettes (the “advanced” Kent Micronite filter contained asbestos) to “low-tar and low-nicotine cigarettes” (which were no less harmful). The latest in the chain of “reduced harm” products are electronic cigarettes. That they are 95% less harmful was claimed in 2014, on the basis of a
Source: www.atsjournals.orgCategories: General Medicine News, PulmonologyTweet
The Blue Journal thanks Simone Cappio Borlino, MD, for his contribution to the October 1 issue The Effect of PEEP on Pulmonary Vascular Resistance Depends on Lung Recruitability in Patients with ARDS https://t.co/fU8SnfzWDc https://t.co/Vf2XZOhyMr