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Mashup Score: 10
Second- or later-line cabozantinib was effective and manageable in a real-world setting and had a safety profile consistent with previous studies.
Categories: General Medicine News, Oncologists1Tweet
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Mashup Score: 6Renal Neuroendocrine Neoplasms: A Single-center Experience - 1 month(s) ago
Micro-AbstractRenal neuroendocrine neoplasms are rare, with little to no data available on prognosis and treatment outcomes. We present the largest single-institution series of 17 patients, with a median follow-up of 62.8 months. After aggressive resection, the median time to recurrence was 18 months, and the median overall survival was 143 months. Somatostatin analogs provided disease stability in 4 of 9 patients.
Categories: General Medicine News, Hem/OncsTweet-
Little data exist on the optimal systemic therapy of the rare renal NETs but as long as they are well diff and SSTR-expressing, the usual NET rules apply... Thanks to @PatrickMcGarrah and others, we do have data on therapy outcomes of this rare cancer. https://t.co/wxBliKDwIV
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Mashup Score: 32Optimizing the use of next-generation sequencing assays in patients with urothelial carcinoma: recommendations by the 2023 San Raffaele Retreat panel - 7 month(s) ago
The application of precision medicine in clinical practice implies a thorough evaluation of actionable genomic alterations to streamline therapeutic decision making. Comprehensive genomic profiling of tumor via next-generation sequencing (NGS) represents a great opportunity but also several challenges. During the 2023 San Raffaele Retreat, we aimed to provide expert recommendations for the optimal use of NGS in urothelial carcinoma (UC).
Categories: General Medicine News, Hem/OncsTweet-
📝📍finally out the first recommendations paper from the #GURetreat @SanRaffaeleMI Optimizing the use of NGS in pts with UC| @vale_tateo @Anto_cigliola @CMercinelli @neerajaiims @PGrivasMDPhD @UroDocAsh @LDyrskjot @y_loriot @shilpaonc @SpiessPhilippe https://t.co/6AsSjM2Cby
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Mashup Score: 31Optimizing the use of next-generation sequencing assays in patients with urothelial carcinoma: recommendations by the 2023 San Raffaele Retreat panel - 8 month(s) ago
The application of precision medicine in clinical practice implies a thorough evaluation of actionable genomic alterations to streamline therapeutic decision making. Comprehensive genomic profiling of tumor via next-generation sequencing (NGS) represents a great opportunity but also several challenges. During the 2023 San Raffaele Retreat, we aimed to provide expert recommendations for the optimal use of NGS in urothelial carcinoma (UC).
Categories: General Medicine News, Hem/OncsTweet-
📝📍finally out the first recommendations paper from the #GURetreat @SanRaffaeleMI Optimizing the use of NGS in pts with UC| @vale_tateo @Anto_cigliola @CMercinelli @neerajaiims @PGrivasMDPhD @UroDocAsh @LDyrskjot @y_loriot @shilpaonc @SpiessPhilippe https://t.co/6AsSjM2Cby
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Mashup Score: 16Management of Metastatic Urothelial Carcinoma in Emerging Markets (EM): An Expert Opinion - 11 month(s) ago
Urothelial carcinoma is the 10th most common cancer globally with an almost 4 times higher prevalence in men. It is more prevalent in elderly population with 80% of the cases getting diagnosed in people above 65 years of age.1-3. Histologically, almost 90% of all bladder cancer cases in the United States and Europe are urothelial in origin. However, in other parts of the world, incidence of non-urothelial forms of bladder cancer have been reported to have increased, chiefly due to endemic schistosomiasis4.
Categories: General Medicine News, Hem/OncsTweet-
The tx of mUC has evolved in the last years, but it is still challenging in the #LIMC. In this review, the authors from different regions discuss the gaps, challenges and suggestions to improve mUC care in the #LMIC. https://t.co/0EaqNbcbsV @BourlonMaite @tompowles1 @raymanneh
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Mashup Score: 9Causal Diagram Techniques for Urologic Oncology Research - 1 year(s) ago
Large quantities of data are now available to medical researchers; however, observational studies are plagued by bias and confounding. Additionally, much of this research only speculates on variable associations, leaving prospective randomized clinical trials as the sole purveyors of claims about causal relations between variables. There has been a growing movement of causal inference that uses new techniques to investigate causality using observational data. These techniques include the implementation of directed acyclic graphs, which allow researchers to explicitly and reproducibly define the causal relationships between study variables, thus making statistical analysis more robust.
Categories: General Medicine News, Hem/OncsTweet-
4/n confounders in our multivariable model (your usual suspects ECOG, age, renal fxn, stage, etc). Mediators (e..g # of cycles) didn’t get “adjust for” given that we already adjusted for the confounders behind them. see https://t.co/USBvChdyym https://t.co/ensF7cNNvS
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A prospective noninterventional real-world study of cabozantinib in pretreated patients with advanced renal cell carcinoma refractory to vascular endothelial growth factor-targeted therapy (CASSIOPE) by @g_procopio_ and team https://t.co/m87zTQxvE3 The CASSIOPE study examined… https://t.co/Nwhb2PDUht