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Mashup Score: 2Risk of Cardiovascular Disease in Cancer Survivors after Systemic Treatment: A Population-Based Cohort Study - 4 hour(s) ago
AbstractBackgroundPatients face an increased risk of cardiovascular disease shortly after a cancer diagnosis, but evidence on long-term risk among cancer survivors remains limited.ObjectivesIn this…
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Mashup Score: 1Long-Term Follow-Up Data on Flecainide Use as an Antiarrhythmic in Arrhythmogenic Right Ventricular Cardiomyopathy: A Multicenter Study - 5 hour(s) ago
AbstractBackgroundArrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited cardiomyopathy associated with a high risk of ventricular arrhythmia (VA). Several animal models have been u…
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Mashup Score: 4Inhibition of Factor XI Using RBD4059: A Novel GalNAc-siRNA With Potent and Durable Antithrombotic Effects - 6 hour(s) ago
Highlights •FXI is an attractive antithrombotic target because of its significant role in thrombosis and minor role in hemostasis.•In the present study, the GalNAc-siRNA molecule RBD4059 showed pro…
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Coagulation factor XI is a promising target for safer anticoagulants. In a series of preclinical studies, novel factor XI-targeting GalNAc-siRNA RBD4059 showed high potency & long-lasting antithrombotic effects w/out ⬆️ 🩸 risk. https://t.co/RG7cJJhyor #JACCBTS #CardioX #cvCoag https://t.co/xJnJ6AHdr2
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Mashup Score: 2The Relevance of the Type of Ventricular Arrhythmia in Titin-Related Dilated Cardiomyopathy: A Multicenter Study - 7 hour(s) ago
AbstractBackgroundTruncating titin variants (TTNtvs) are the most prevalent cause of inherited dilated cardiomyopathy. Occurrence of different ventricular arrhythmia (VA) subtypes, including premat…
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Mashup Score: 0A Re-Examination of the 2018 Heart Allocation Policy Change: Embracing Progress Over Perfection - 10 hour(s) ago
Corresponding Author
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Mashup Score: 15Association of the 2018 U.S. Heart Allocation Policy Change and the Survival Benefit of Heart Transplantation: - 10 hour(s) ago
AbstractBackgroundIn 2018, the U.S. heart allocation policy underwent a major change designed to increase the transplantation of the most medically urgent candidates.ObjectivesThis study aims to de…
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Mashup Score: 11JACC new brand - 11 hour(s) ago
“Transitions are opportunities. They are full of possibilities, marking a juncture that combines an end and a beginning.” — Harlan M. Krumholz, MD, SM, FACC, JACC Editor-in-Chief After a year of thoughtful consideration and planning, we are excited to introduce a redesigned, refined and reimagined JACC, starting in July. This effort is another step in our journey to usher in a new era that honors the past while positioning the journal as a leading beacon to advance global cardiovascular health. Streamlined
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Mashup Score: 224
Gurusher S. Panjrath, MBBS, FACC, Chair Nicole M. Bhave, MD, FACC, Immediate Past Chair ∗ Chayakrit Krittanawong, MD, FACC Barbara Wiggins, P harm D, FACC Megan Coylewright, MD, MPH, FACC, Ex Officio 2. Assumptions and Definitions 3 2.1. Assumptions and Definitions 3 2.3. Etiology and Pathophysiology of Obesity 3 2.4. Risks Associated With Obesity 4 Figure 2. Obesity Management for Optimization of Cardiovascular Health 5 4. Description, Rationale, and Implications for Medical Therapies 5 4.1. Rationale
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Mashup Score: 21Challenges and Strategies for Deep Learning in Cardiovascular Imaging: Ejection Fraction and Heart Failure Management - 1 day(s) ago
AbstractBackgroundAutomated measurements in cardiac imaging with the use of deep learning (DL) is a highly active area of research and innovation. However, some concerns challenge the translation o…
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Pitfalls and promise in #AI/DL #EchoFirst: how to best evaluate the evaluation metrics to address bias? New #JACCIMG study evaluates 3 common challenges in EF estimation to mitigate these challenges for new AI/DL frameworks in #cvImaging. https://t.co/loAz4Xodgm #DeepLearning https://t.co/rmZ6tSy7vq
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Mashup Score: 4Blood Pressure Lowering and Risk of Cancer: Individual Participant-Level Data Meta-Analysis and Mendelian Randomization Studies - 1 day(s) ago
AbstractBackgroundPharmacologic blood pressure (BP) lowering is typically a lifelong treatment, and both clinicians and patients may have concerns about the long-term use of antihypertensive agents…
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Using Danish population-based registries, #JACCCardioOnc study found elevated long-term #CVrisk in cancer survivors post systemic therapy 🔹HF/cardiomyopathy (HR 1.08) 🔹#VTE (HR 1.50) 🔹#Myocarditis/pericarditis (HR 1.30) 🔹Kidney failure (HR 1.17) 🔗 https://t.co/fdFs7aUlwi https://t.co/EfsFYJ7yi1