Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study

An unenhanced CT tumour attenuation cutoff of 20 HU should replace that of 10 HU for exclusion of ACC. A triple test strategy of tumour diameter, imaging characteristics, and urine steroid metabolomics improves detection of ACC, which could shorten time to surgery for patients with ACC and help to avoid unnecessary surgery in patients with benign tumours.

A multi-test strategy for adrenal tumours

Broadening access to technology and its rapid evolution have transformed clinical care over the past half century. CT and MRI became widely available around 1980, and performance has steadily improved since. Incidental adrenal nodules were detected in only 0·4% of patients undergoing CT scans in the mid to late 1980s, but cross-sectional imaging studies now detect adrenal incidentalomas at least…

Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study

An unenhanced CT tumour attenuation cutoff of 20 HU should replace that of 10 HU for exclusion of ACC. A triple test strategy of tumour diameter, imaging characteristics, and urine steroid metabolomics improves detection of ACC, which could shorten time to surgery for patients with ACC and help to avoid unnecessary surgery in patients with benign tumours.

A multi-test strategy for adrenal tumours

Broadening access to technology and its rapid evolution have transformed clinical care over the past half century. CT and MRI became widely available around 1980, and performance has steadily improved since. Incidental adrenal nodules were detected in only 0·4% of patients undergoing CT scans in the mid to late 1980s, but cross-sectional imaging studies now detect adrenal incidentalomas at least…

Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study

An unenhanced CT tumour attenuation cutoff of 20 HU should replace that of 10 HU for exclusion of ACC. A triple test strategy of tumour diameter, imaging characteristics, and urine steroid metabolomics improves detection of ACC, which could shorten time to surgery for patients with ACC and help to avoid unnecessary surgery in patients with benign tumours.

A multi-test strategy for adrenal tumours

Broadening access to technology and its rapid evolution have transformed clinical care over the past half century. CT and MRI became widely available around 1980, and performance has steadily improved since. Incidental adrenal nodules were detected in only 0·4% of patients undergoing CT scans in the mid to late 1980s, but cross-sectional imaging studies now detect adrenal incidentalomas at least…

Our Response to COVID-19 as Endocrinologists and Diabetologists

In our professional lives, we have not witnessed a healthcare crisis of this magnitude and severity. As we proof this (March 30, 2020), COVID-19, caused by the

Adrenocortical carcinoma — towards genomics guided clinical care

Adrenocortical carcinoma (ACC) is a rare and aggressive neoplasm that arises in the adrenal gland cortex. This Review highlights how genomics can be used to stratify ACC and potentially improve clinical care, outcomes and patient quality of life.

Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study

An unenhanced CT tumour attenuation cutoff of 20 HU should replace that of 10 HU for exclusion of ACC. A triple test strategy of tumour diameter, imaging characteristics, and urine steroid metabolomics improves detection of ACC, which could shorten time to surgery for patients with ACC and help to avoid unnecessary surgery in patients with benign tumours.

Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study

An unenhanced CT tumour attenuation cutoff of 20 HU should replace that of 10 HU for exclusion of ACC. A triple test strategy of tumour diameter, imaging characteristics, and urine steroid metabolomics improves detection of ACC, which could shorten time to surgery for patients with ACC and help to avoid unnecessary surgery in patients with benign tumours.