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Mashup Score: 12Artificial Intelligence Identifies Novel Disease Pathways - 11 day(s) ago
Software pinpoints signs of breast cancer that genomic testing can miss.
Source: aacrjournals.orgCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 18Early Detection of Advanced Adenomas and Colorectal Carcinoma by Serum Glycoproteome Profiling - 3 month(s) ago
Colorectal cancer (CRC) remains a significant cause of cancer related deaths globally, particularly in the Western world. In the United States, it is the fourth most common cancer and the second deadliest, with incidence rates rising in younger age groups.1 Despite available screening tests, around 30% of eligible Americans aged 45–75 years have not undergone recommended screening, attributed to various reasons like fear, lack of awareness, and cost.2,3 There is a clear need for novel, noninvasive, and cost-effective screening modalities.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 6The Tumor Immune Microenvironment Architecture Correlates with Risk of Recurrence in Head and Neck Squamous Cell Carcinoma - 4 month(s) ago
Imaging the spatial tumor immune microenvironment and evaluating the presence of type 1 tertiary lymphoid structures enables prediction of recurrence after surgery in patients with head and neck squamous cell carcinoma.
Source: aacrjournals.orgCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 1The Tumor Immune Microenvironment Architecture Correlates with Risk of Recurrence in Head and Neck Squamous Cell Carcinoma - 4 month(s) ago
Imaging the spatial tumor immune microenvironment and evaluating the presence of type 1 tertiary lymphoid structures enables prediction of recurrence after surgery in patients with head and neck squamous cell carcinoma.
Source: aacrjournals.orgCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 0
Adjuvant mitotane might not be indicated in patients with low-grade, localised adrenocortical carcinoma considering the relatively good prognosis of these patients, and no significant improvement in recurrence-free survival and treatment-associated toxicity in the mitotane group. However, the study was discontinued prematurely due to slow recruitment and cannot rule out an efficacy of treatment.
Source: www.thelancet.comCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 0
Recently, a man aged 50 years came to my office. He had received surgery for a right-sided non-functional adrenocortical carcinoma measuring 11 cm in diameter and had been referred to discuss adjuvant treatment. Based on adrenal histology findings, he had a European Network for the Study of Adrenal Tumors (ENS@T) tumour stage II, which means no lymph node metastases, and a [18F]fluorodeoxyglucose-PET scan had ruled out distant metastasis.1 Fortunately, he had undergone oncological tumour resection resulting in complete resection.
Source: www.thelancet.comCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 2Tipifarnib Potentiates the Antitumor Effects of PI3Kα Inhibition in PIK3CA- and HRAS-Dysregulated HNSCC via Convergent Inhibition of mTOR Activity - 6 month(s) ago
The mechanistically designed, biomarker-matched strategy of combining alpelisib and tipifarnib is efficacious in PIK3CA- and HRAS-dysregulated head and neck squamous carcinoma and could improve outcomes for many patients with recurrent, metastatic disease.
Source: aacrjournals.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Attending #Targets23? Read article in new issue on how the farnesyltransferase inhibitor tipifarnib potentiates the antitumor effects of PI3Kα inhibition in head and neck squamous cell #carcinoma via convergent inhibition of mTOR activity. https://t.co/7RR9husbGu @kuraoncology https://t.co/cbemA8nyRx
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Mashup Score: 1
Recently, a man aged 50 years came to my office. He had received surgery for a right-sided non-functional adrenocortical carcinoma measuring 11 cm in diameter and had been referred to discuss adjuvant treatment. Based on adrenal histology findings, he had a European Network for the Study of Adrenal Tumors (ENS@T) tumour stage II, which means no lymph node metastases, and a [18F]fluorodeoxyglucose-PET scan had ruled out distant metastasis.1 Fortunately, he had undergone oncological tumour resection resulting in complete resection.
Source: www.thelancet.comCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 0
Adjuvant mitotane might not be indicated in patients with low-grade, localised adrenocortical carcinoma considering the relatively good prognosis of these patients, and no significant improvement in recurrence-free survival and treatment-associated toxicity in the mitotane group. However, the study was discontinued prematurely due to slow recruitment and cannot rule out an efficacy of treatment.
Source: www.thelancet.comCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 0Intratumoral Microbiota Composition Regulates Chemoimmunotherapy Response in Esophageal Squamous Cell Carcinoma - 7 month(s) ago
Analysis of intratumoral microbiota in patients with esophageal cancer identifies a microbiota signature that is associated with chemoimmunotherapy response and reveals that Streptococcus induces a favorable response by stimulating CD8+ T-cell infiltration.
Source: aacrjournals.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
Be sure to check out this news article related to the talk, by @FresiaPareja covering artificial intelligence and the unveiling of mechanisms of CDH1 inactivation in breast invasive lobular #carcinoma: https://t.co/IkMQ7irb68 https://t.co/Vhhu42OJrs