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    This cross-sectional study examines antibiotic exposure, days of therapy, types of antibiotics, and changes in use patterns among newborns in neonatal intensive care units (NICUs) across the US from 2009 to 2021.

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    • A study in @JAMAPediatrics by @dus10flan et al evaluates trends in antibiotic use in U.S. NICUs from 2009 to 2021 https://t.co/j4JaQhkzvM #EBNEOalerts #neoEBM #neotwitter https://t.co/6XG6PL4wqV

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    This secondary analysis of the TOP NIRS randomized clinical trial evaluates associations of red blood cell transfusion and low cerebral saturation with outcomes in preterm infants.

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    • A secondary analysis of the TOP trial in @JAMANetworkOpen examines whether RBC transfusion is associated with changes in cerebral/tissue saturation/extraction and associated with neurodevelopmental outcomes https://t.co/rZRzYPdIIi #EBNEOalerts #neoEBM #neotwitter https://t.co/kzZ4xp90fY

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    Abstract. Objectives: Corticosteroids are used to prevent or treat lung disease of prematurity. While neurological side effects have been reported, detailed effects on cerebellar growth are unknown. This study aimed to compare cerebellar growth in premature infants who received dexamethasone or hydrocortisone to premature infants who did not receive postnatal corticosteroids. Study Design: Retrospective case-control study in infants born at a gestational age of <29 weeks and admitted to two level 3 neonatal intensive care units. Exclusion criteria were severe congenital anomalies and cerebellar or severe supratentorial lesions. Infants were treated with dexamethasone (unit 1) or hydrocortisone (unit 2) for chronic lung disease. Controls (unit 1) did not receive postnatal corticosteroids. Sequential head circumference (HC) and ultrasound measurements of transcerebellar diameter (TCD), biparietal diameter (BPD), and corpus callosum-fastigium length (CCFL) were performed until 40 weeks’ p

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    • A retrospective case-control study looking at the association of dexamethasone and hydrocortisone with cerebellar growth in preterm infants @WCHKarger https://t.co/Opcy71ad7E #neotwitter #neoEBM #EBNEOalerts https://t.co/Q537lYNLvA

  • Mashup Score: 6

    OBJECTIVES:. In infants with hypoxic-ischemic encephalopathy (HIE), conflicting information on the association between early glucose homeostasis and outcome exists. We characterized glycemic profiles in the first 12 hours after birth and their association with death and neurodevelopmental impairment (NDI) in neonates with moderate or severe HIE undergoing therapeutic hypothermia.METHODS:. This…

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    • Post-hoc analysis of HEAL trial shows that early glycemic state in infants with HIE differs according to severity & is associated with outcomes. @aap_peds Original article: https://t.co/olUehclhH7 Commentary: https://t.co/ll6JEtq9et #neotwitter #neoEBM #ebneoalerts https://t.co/FRde3A4zyW