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Mashup Score: 0
Single-cell methods for measuring chromatin accessibility (ATAC-seq) and gene expression (RNA-seq) are rapidly evolving, but tools to integrate data and infer gene-regulatory relationships remain limited. Here we generate multi-omics data of resting and stimulated human blood cells and present a new computational framework for constructing gene-regulatory networks (GRNs). Specifically, we describe functional inference of gene regulation (FigR), a workflow to (1) pair scATAC-seq with scRNA-seq, (2) connect cis-regulatory elements to target genes, and (3) identify TF-gene relationships.
Source: www.cell.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 3Engineered repeat proteins as scaffolds to assemble multi-enzyme systems for efficient cell-free biosynthesis - Nature Communications - 11 month(s) ago
Multi-enzymatic cascades benefit from precise nanometric organization but achieving this using available scaffolds is challenging. Here the authors present strategy for organizing multienzymatic systems using a protein scaffold based on TRAP domains, and demonstrate improved catalytic output.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0Online Event - 2 year(s) ago
Thursday, October 27, 2022 | 12:30 PM ET Omics technologies have emerged as powerful tools that are used to investigate broad scientific questions. In this webinar, we delve into how omics has been used to identify leads in drug discovery. Sven Nelander (Uppsala University) will discuss how omics can be used to identify therapeutic opportunities for…
Source: www.workcast.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0Online Event - 2 year(s) ago
Thursday, October 27, 2022 | 12:30 PM ET Omics technologies have emerged as powerful tools that are used to investigate broad scientific questions. In this webinar, we delve into how omics has been used to identify leads in drug discovery. Sven Nelander (Uppsala University) will discuss how omics can be used to identify therapeutic opportunities for…
Source: www.workcast.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0Online Event - 2 year(s) ago
Thursday, October 27, 2022 | 12:30 PM ET Omics technologies have emerged as powerful tools that are used to investigate broad scientific questions. In this webinar, we delve into how omics has been used to identify leads in drug discovery. Sven Nelander (Uppsala University) will discuss how omics can be used to identify therapeutic opportunities for…
Source: www.workcast.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 1Online Event - 2 year(s) ago
Thursday, October 27, 2022 | 12:30 PM ET Omics technologies have emerged as powerful tools that are used to investigate broad scientific questions. In this webinar, we delve into how omics has been used to identify leads in drug discovery. Sven Nelander (Uppsala University) will discuss how omics can be used to identify therapeutic opportunities for…
Source: www.workcast.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0Online Event - 2 year(s) ago
Thursday, October 27, 2022 | 12:30 PM ET Omics technologies have emerged as powerful tools that are used to investigate broad scientific questions. In this webinar, we delve into how omics has been used to identify leads in drug discovery. Sven Nelander (Uppsala University) will discuss how omics can be used to identify therapeutic opportunities for…
Source: www.workcast.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 3Online Event - 2 year(s) ago
Thursday, October 27, 2022 | 12:30 PM ET Omics technologies have emerged as powerful tools that are used to investigate broad scientific questions. In this webinar, we delve into how omics has been used to identify leads in drug discovery. Sven Nelander (Uppsala University) will discuss how omics can be used to identify therapeutic opportunities for…
Source: www.workcast.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 6Online Event - 2 year(s) ago
Thursday, October 27, 2022 | 12:30 PM ET Omics technologies have emerged as powerful tools that are used to investigate broad scientific questions. In this webinar, we delve into how omics has been used to identify leads in drug discovery. Sven Nelander (Uppsala University) will discuss how omics can be used to identify therapeutic opportunities for…
Source: www.workcast.comCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 1Online Event - 2 year(s) ago
Thursday, October 27, 2022 | 12:30 PM ET Omics technologies have emerged as powerful tools that are used to investigate broad scientific questions. In this webinar, we delve into how omics has been used to identify leads in drug discovery. Sven Nelander (Uppsala University) will discuss how omics can be used to identify therapeutic opportunities for…
Source: www.workcast.comCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
Functional inference of #generegulation using single-cell #multi-omics Freely available top-read @CellGenomics paper @JD_Buenrostro https://t.co/RZe5Yex9s7 https://t.co/E0LRc3Iz25