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    Researchers have discovered a link between neurotoxicity related to chimeric antigen receptor T-cell therapy and development of subsequent hypophosphatemia.Results of their prospective analysis, published in Cancer Immunology Research, suggest incidence and severity of CAR T-cell therapy complication known as immune effector cell-associated neurotoxicity syndrome (ICANS) are associated with

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    • CAR T-cell therapy-related #neurotoxicity linked to low blood phosphate levels. https://t.co/Ny44rBAjrm #tcell #phosphate @UCLAJCCC #HemOnc #OncAlert #MedEd

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    Patients who develop potentially serious neurotoxicity show elevated plasma levels of neurofilament light chain prior to the treatment, suggesting it could be predictor of risk for this side effect.

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    • Patients undergoing CAR T-cell therapy who develop potentially serious #neurotoxicity from the therapy show elevated plasma levels of neurofilament light chain prior to the treatment, suggesting a possible predictor of risk for the side effect. #OncTwitter https://t.co/kUrZ8NkeFZ

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    Identifiqueu-vos amb el nom d’usuari i la contrasenya de la Intranet UB. Començareu una sessió que us donarà accés als serveis de la Universitat que requereixen identificació UB Per poder autenticar-vos és necessari introduir correctament la targeta amb el…

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    • Updated and interesting case report of #neurotoxicity in #CART patient @NEJM Confused about Confusion | NEJM https://t.co/zW0BmM97Is

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    Objective: To examine the relationship between transcranial doppler (TCD) mean flow velocity (MFV) and the severity and temporal onset of neurotoxicity after chimeric antigen receptor (CAR) T-cell therapy in patients with relapsed lymphoma. Methods: We identified a cohort of 165 patients with relapsed or refractory B-cell lymphoma who received CAR T-cell therapy. TCDs were performed at baseline,…

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    • #Transcranial doppler ultrasound may act a functional biomarker in patients who received chimeric antigen receptor (CAR) T-cell therapy, to help guide decision making around length of hospital stay and immunologic interventions for #neurotoxicity. https://t.co/H90L7FJNL8 https://t.co/OnHfBj3Xie

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    Wolters Kluwer Health - 3 year(s) ago

    JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable…

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    • What are the #EEG findings in adults & children with immune effector cell-associated #neurotoxicity syndrome? Do these correlate with neurotoxicity scored by CTCAE & CAPD Delirium scores? For answers to these questions & more, read https://t.co/o6LTyIHAY4 @UofWA @seattlechildren