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Mashup Score: 0
Dengue Fever and Betacoronavirus infections are widespread and dangerous. The cofounder and CEO of Emergex answers questions about them and upcoming Phase II and Phase III studies.
Source: Infection Control TodayCategories: Infectious Disease, Latest HeadlinesTweet
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Mashup Score: 2
Dengue Fever and Betacoronavirus infections are widespread and dangerous. The cofounder and CEO of Emergex answers questions about them and upcoming Phase II and Phase III studies.
Source: Infection Control TodayCategories: Infectious Disease, Latest HeadlinesTweet-
Dengue Fever and Betacoronavirus infections are widespread and dangerous. The cofounder and CEO of Emergex answers questions about them and upcoming Phase II and Phase III studies. https://t.co/NsO8ffBPOJ @EmergexVaccines #dengue #MERS #SARS_CoV_2 #mosquitoborne #RNA
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Mashup Score: 7Renaissance of glucocorticoids in critical care in the era of COVID-19: ten urging questions - Critical Care - 2 year(s) ago
The 40-year-old experience with glucocorticosteroids (GCs) in the context of severe infections is complex and troublesome. Recently, however, a clear indication for GCs in severe COVID-19 has been established. This may constitute a harbinger of a wider use of GCs in critical illnesses. A fundamental prerequisite of such an action is a better understanding of the heterogeneity of critical illness…
Source: BioMed CentralCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OpenAccess 10 major questions regarding the use of #glucocorticosteroids in #critical_care that must be answered in the era of #COVID19 https://t.co/Kf8JOk9HsM @jlvincen @ISICEM #FOAMed #FOAMcc #critical_illness #SARS_CoV_2 https://t.co/SMVk7nuVnX
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Mashup Score: 1Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein - Critical Care - 2 year(s) ago
Background SARS-CoV-2 infection leads to acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Both clinical data and animal experiments suggest that the renin–angiotensin system (RAS) is involved in the pathogenesis of SARS-CoV-2-induced ALI. Angiotensin-converting enzyme 2 (ACE2) is the functional receptor for SARS-CoV-2 and a crucial negative regulator of RAS. Recombinant…
Source: BioMed CentralCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OpenAccess Recombinant #ACE2 plays a protective role against #SARS_CoV_2 lung injury https://t.co/WfbH5mvp0W @jlvincen @ISICEM #FOAMed #FOAMcc #BMC #ICU #rACE2 #pandemics #virus #spike_protein https://t.co/IIRovoP94w
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Mashup Score: 0Lack of SARS-CoV-2-specific cellular response in critically ill COVID-19 patients despite apparent effective vaccination - Critical Care - 2 year(s) ago
Correspondence Open Access Published: 08 June 2022 Critical Care volume 26, Article number: 170 (2022) Cite this article …
Source: BioMed CentralCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OpenAccess #COVID19: Lack of #SARS_CoV_2-specific cellular response despite #vaccination https://t.co/QAkjE78K2A @jlvincen @ISICEM #FOAMed #FOAMcc #BMC #ICU #pandemics #comorbidity #aging #immune_response https://t.co/xyHpTmHYbx
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Mashup Score: 4TTCOV19: timing of tracheotomy in SARS-CoV-2-infected patients: a multicentre, single-blinded, randomized, controlled trial - Critical Care - 2 year(s) ago
Background Critically ill COVID-19 patients may develop acute respiratory distress syndrome and the need for respiratory support, including mechanical ventilation in the intensive care unit. Previous observational studies have suggested early tracheotomy to be advantageous. The aim of this parallel, multicentre, single-blinded, randomized controlled trial was to evaluate the optimal timing of…
Source: BioMed CentralCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OpenAccess #COVID19: What’s the optimal timing for #tracheotomy? https://t.co/0RC1CPE7UI @jlvincen @ISICEM #FOAMed #FOAMcc #BMC #ICU #SARS_CoV_2 #pandemics #Mechanical_ventilation https://t.co/4wAcQu616R
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Mashup Score: 1Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis - Critical Care - 2 year(s) ago
Background The role of neuromuscular blocking agents (NMBAs) in coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (ARDS) is not fully elucidated. Therefore, we aimed to investigate in COVID-19 patients with moderate-to-severe ARDS the impact of early use of NMBAs on 90-day mortality, through propensity score (PS) matching analysis. Methods We analyzed a convenience sample of…
Source: BioMed CentralCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OA #COVID19: the impact of early use of #neuromuscular_blocking_agents on 90-day #mortality https://t.co/pJzkT46JwW #FOAMed #FOAMcc #BMC @ISICEM @jlvincen #ICU #SARS_CoV_2 #pandemics #NMBAs #Mechanical_ventilation https://t.co/EKhniahOnt
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Mashup Score: 4Study: Antiviral gene known to block HIV also shows potent activity against SARS-CoV-2 - 2 year(s) ago
In the ‘eternal arms race’ between pathogen and host, cells employ the same gene to fight both SARS-CoV-2 and HIV, revealing new avenues for potential therapies.
Source: www.buffalo.eduCategories: General Medicine News, Latest HeadlinesTweet-
Antiviral gene known to block HIV also shows potent activity against #SARS_CoV_2 @LabStavrou @UBuffalo @UBmednews https://t.co/TEDxyqkqMq
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Mashup Score: 2Very late intubation in COVID-19 patients: a forgotten prognosis factor? - Critical Care - 2 year(s) ago
Description of all consecutive critically ill COVID 19 patients hospitalized in ICU in University Hospital of Guadeloupe and outcome according to delay between steroid therapy initiation and mechanical ventilation onset. Very late mechanical ventilation defined as intubation after day 7 of dexamethasone therapy was associated with grim prognosis and a high mortality rate of 87%.
Source: BioMed CentralCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OpenAccess #COVID19: #intubation after day 7 of #dexamethasone therapy & associated prognosis https://t.co/1BMhEYRMkh @jlvincen @ISICEM @ESPNIC_Society #FOAMed #FOAMcc #BMC #ICU #Sars_Cov_2 #pandemic https://t.co/BVWXq7MA11
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Mashup Score: 16STINGing type I IFN-mediated immunopathology in COVID-19 - 2 year(s) ago
The molecular basis for type I interferon (IFN)-mediated immunopathology is unclear. New data now identify the cGAS–STING pathway as a major driver of pathological type I IFN responses in COVID-19.
Source: www.nature.comCategories: Allergy-Immunology, Latest HeadlinesTweet-
Andreakos discusses in @NatImmunol two new studies on how #SARS_CoV_2 infection triggers type I IFN-mediated immunopathology @VangelisAndrea1 https://t.co/djm2p3Sjtr https://t.co/Z2TCOMjYON
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Need information on Dengue Fever and Betacoronavirus? ICT asked Emergex's CEO for updates on Phase II and III studies. https://t.co/PmQefBpFYV @EmergexVaccines #dengue #MERS #SARS_CoV_2 #mosquitoborne #RNA