• Mashup Score: 3
    Restoration of Quality of Life and Functional Recovery After Colorectal Cancer Surgery in Older Adults - 9 month(s) ago

    In the article that accompanies this editorial, Montroni et al 4 report prospectively collected 3-month and 6-month postoperative quality-of-life and functional recovery data after elective colorectal cancer resections among 625 older adults and demonstrated that approximately 70% will have preserved or improved quality of life, and 76% will have postoperative functional recovery over this extended period. These findings provide benchmark information that surgeons and others should use to help counsel

    Source: ascopubs.org
    Categories: Hem/Onc News and Journals, Latest Headlines
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      ASCO_pubs

      šŸ“£ #JCO #Editorial: Restoration of Quality of Life and Functional Recovery Following #ColorectalCancer Surgery in Older Adults āž”ļø https://t.co/jGNkiQPOvj #gerionc #surgonc @apl2018 @FergaljFleming https://t.co/U5cgobo7S5

  • Mashup Score: 0
    Predicting Functional Recovery and Quality of Life in Older Patients Undergoing Colorectal Cancer Surgery: Real-World Data From the International GOSAFE Study - 9 month(s) ago

    PURPOSE The GOSAFE study evaluates risk factors for failing to achieve good quality of life (QoL) and functional recovery (FR) in older patients undergoing surgery for colon and rectal cancer. METHODS Patients age 70 years and older undergoing major elective colorectal surgery were prospectively enrolled. Frailty assessment was performed and outcomes, including QoL (EQ-5D-3L) recorded (3/6 months postoperatively). Postoperative FR was defined as a combination of Activity of Daily Living ā‰„5 + Timed Up & Go test <20 seconds + MiniCog >2. RESULTS Prospective complete data were available for 625/646 consecutive patients (96.9%; 435 colon and 190 rectal cancer), 52.6% men, and median age was 79.0 years (IQR, 74.6-82.9 years). Surgery was minimally invasive in 73% of patients (321/435 colon; 135/190 rectum). At 3-6 months, 68.9%-70.3% patients experienced equal/better QoL (72.8%-72.9% colon, 60.1%-63.9% rectal cancer). At logistic regression analysis, preoperative Flemish Triage Risk Screeni

    Source: ascopubs.org
    Categories: Hem/Onc News and Journals, Latest Headlines
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      ASCO_pubs

      šŸ¤” Can older ptsā€™ #QOL+Function be restored after #ColorectalCancer surg? šŸ™Œ @GOSAFEstudy shows majority can! āž”ļø https://t.co/ntNm3Zyyqv #surgonc #gerionc @3isac @ugolinimd @raaudisio @SWexner @AntoninoSpin https://t.co/h5KuR3pgik

  • Mashup Score: 1
    Intraoperative MRI-Guided Resection Is Not Superior to 5-Aminolevulinic Acid Guidance in Newly Diagnosed Glioblastoma: A Prospective Controlled Multicenter Clinical Trial - 9 month(s) ago

    PURPOSE Prospective data suggested a superiority of intraoperative MRI (iMRI) over 5-aminolevulinic acid (5-ALA) for achieving complete resections of contrast enhancement in glioblastoma surgery. We investigated this hypothesis in a prospective clinical trial and correlated residual disease volumes with clinical outcome in newly diagnosed glioblastoma. METHODS This is a prospective controlled multicenter parallel-group trial with two center-specific treatment arms (5-ALA and iMRI) and blinded evaluation. The primary end point was complete resection of contrast enhancement on early postoperative MRI. We assessed resectability and extent of resection by an independent blinded centralized review of preoperative and postoperative MRI with 1-mm slices. Secondary end points included progression-free survival (PFS) and overall survival (OS), patient-reported quality of life, and clinical parameters. RESULTS We recruited 314 patients with newly diagnosed glioblastomas at 11 German centers. A t

    Source: ascopubs.org
    Categories: Hem/Onc News and Journals, Latest Headlines
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      āŒ IMRI-guided resection of #glioblastoma was not superior to 5-ALA in a prospective controlled trial āž”ļø https://t.co/K41lKH244L #BTSM #surgonc #oncorad https://t.co/d13ol6c0KD

  • Mashup Score: 0
    JNCCN 360 - Breast - Role of Preoperative MRI in Breast-Conserving Surgery - 10 month(s) ago

    By: Emily Rhode Posted: Tuesday, May 30, 2023 A first-of-its-kind trial used randomized stratification based on mammographic density to evaluate the performance of preoperative MRI in different subgroups of patients with breast cancer. It has shown that the use of breast MRI may lead to higher mastectomy rates and does…

    Source: jnccn360.org
    Categories: Hem/Onc News and Journals, Latest Headlines
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      JNCCN

      Role of Preoperative MRI in Breast-Conserving Surgery: https://t.co/SWunt8nfz8 #JNCCN360 #BCSM #BreastCancer #surgonc https://t.co/hdG9knKNax

  • Mashup Score: 1
    Specialist Palliative Care for Patients Undergoing Major Abdominal Surgery for Cancer - 11 month(s) ago

    This randomized clinical trial investigates if patients who undergo nonpalliative surgery for abdominal cancer should receive early specialist palliative care.

    Source: jamanetwork.com
    Categories: Hem/Oncs, Latest Headlines
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      RyanNipp

      Effects of Specialist Palliative Care for Patients Undergoing Major Abdominal Surgery for #Cancer: A Randomized Clinical Trial. https://t.co/80KNNyiJBK @mcshinalljr @WesElyMD @JAMA_current @JAMAOnc @JAMASurgery @VUMC_Cancer #PallOnc #SurgOnc #GeriOnc #PalliativeCare https://t.co/TOkJ0jejyF

  • Mashup Score: 3
    Adjuvant Treatments for Resected Nonā€“Small Cell Lung Cancer Harboring EGFR Mutations - 11 month(s) ago

    This review reports current evidence on outcomes of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor treatment in patients with resectable EGFR mutationā€“positive nonā€“small cell lung cancer.

    Source: jamanetwork.com
    Categories: Hem/Oncs, Latest Headlines
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      mtmdphd

      Adjuvant Treatments for Surgically Resected Nonā€“Small Cell Lung Cancer [NSCLC] Harboring EGFR Mutations: A Review [May 11, 2023] @APassaroMD @TonyMok9 @IlariaAttiliMD Wu, Tsuboi, de Marinis, @peters_solange @JAMAOnc https://t.co/e7YFUtlVvo #lcsm #PrecisionMedicine #surgonc https://t.co/dCky07nMoV

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