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Mashup Score: 4The prognostic utility of protein C as a biomarker for adult sepsis: a systematic review and meta-analysis - Critical Care - 2 year(s) ago
Background Sepsis, the dysregulated host response to infection, triggers abnormal pro-coagulant and pro-inflammatory host responses. Limitations in early disease intervention highlight the need for effective diagnostic and prognostic biomarkers. Protein C’s role as an anticoagulant and anti-inflammatory molecule makes it an appealing target for sepsis biomarker studies. This meta-analysis aims to…
Source: BioMed CentralCategories: Critical Care, Latest HeadlinesTweet
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Mashup Score: 6
Background It is unclear whether vasopressors can be safely administered through a peripheral intravenous (PIV). Systematic review and meta-analysis methodology was used to examine the incidence of local anatomic adverse events associated with PIV vasopressor administration in patients of any age cared for in any acute care environment. Methods MEDLINE, EMBASE, CINAHL, the Cochrane Central…
Source: Critical CareCategories: Critical Care, Latest HeadlinesTweet
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Mashup Score: 1Timing of norepinephrine initiation in patients with septic shock: a systematic review and meta-analysis - 4 year(s) ago
The effect of the timing of norepinephrine initiation on clinical outcomes in patients with septic shock is uncertain. A systematic review and meta-analysis was performed to evaluate the impact of early and late start of norepinephrine support on clinical outcomes in patients with septic shock. We searched the PubMed, Cochrane, and Embase databases for randomized controlled trials (RCTs) and…
Source: Critical CareCategories: Critical Care, Latest HeadlinesTweet
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Mashup Score: 8Prevalence and impact of acute renal impairment on COVID-19: a systematic review and meta-analysis - 4 year(s) ago
The aim of this study is to assess the prevalence of abnormal urine analysis and kidney dysfunction in COVID-19 patients and to determine the association of acute kidney injury (AKI) with the severity and prognosis of COVID-19 patients. The electronic database of Embase and PubMed were searched for relevant studies. A meta-analysis of eligible studies that reported the prevalence of abnormal…
Source: Critical CareCategories: Critical Care, Latest HeadlinesTweet
#CritCare #OpenAccess #Diagnostic and #prognostic value of #proteinC as a #biomarker for adult #sepsis https://t.co/JBapaiWwfG @jlvincen @ISICEM #FOAMed #FOAMcc #BMC #ICU #inflammation #anticoagulant #septic_shock #infection #systematic_review https://t.co/jeUc5UJ2I4