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Mashup Score: 0
Key Points. MSRE-qPCR is an accurate and rapid method to determine TSDR methylation status.MSRE-qPCR produces similar results to previously described orthogonal
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 3HERV1-env Induces Unfolded Protein Response Activation in Autoimmune Liver Disease: A Potential Mechanism for Regulatory T Cell Dysfunction - 1 year(s) ago
Key Points. The liver microenvironment in AIH and dnAIH is enriched with HERV1-env.HERV1-env induced loss of Treg suppressor function in dnAIH.Our results, to o
Categories: Allergy-Immunology, Latest HeadlinesTweet-
Interactions between #HumanEndogenousRetrovirus1 proteins in Tregs identify ER stress and UPR activation as key factors driving #Treg plasticity | from Udeme D. Ekong @GUMedicine | #ReadTheJI #immunology 👉 https://t.co/9GOtt5D6C6 https://t.co/rRThSTrx2P
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Mashup Score: 0Layilin Anchors Regulatory T Cells in Skin - 1 year(s) ago
Key Points. Layilin is expressed by highly activated Tregs in healthy and diseased human skin.In vivo, layilin attenuates Treg suppressive capacity.Layilin cont
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#ICYMI from Michael D. Rosenblum @Treg_Mike @UCSF | The #CtypeLectin #Layilin facilitates #Treg accumulation and anchoring in inflamed #skin | #ReadTheJI #immunology #inflammation 👉 https://t.co/8hyO3i9V8p https://t.co/x2iromZ3xP
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Mashup Score: 1
Northwestern Medicine scientists have identified a new therapeutic target against tumor cells and developed a compound which slows tumor growth and bolsters immune response.
Source: News CenterCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
A study from Deyu Fang, PhD, @LurieCancer, defines the first molecular pathway controlling #Treg fitness and identified a new therapeutic target for tumor treatment, according to findings published in @ScienceAdvances. https://t.co/I8Wfv36j4O via @NUFeinbergMed
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Mashup Score: 1
Background: Mesenchymal stem cell (MSC)-derived exosomes are well recognized immunomodulating agents for cardiac repair, while the detailed mechanisms remain elusive. The Pericardial drainage pathway
Source: Circulation ResearchCategories: Cardiology News and Journals, Latest HeadlinesTweet-
Zhu & colleagues demonstrated that activating #Foxo3 in MHC-II+ #APCs induce #Treg differentiation, cardiac #inflammation resolution & cardiac repair after #MI. Learn more at https://t.co/T1d9ckyNJ4 https://t.co/VIXgevqePS
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Mashup Score: 2Epitope Mapping of Therapeutic Antibodies Targeting Human LAG3 - 2 year(s) ago
This article is featured in Top Reads , p.[][1] [1]: /lookup/volpage/209/1419
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
#JI_TopRead from Roy A Mariuzza @UMD_IBBR using multiple #mAbs with distinct D1 #epitopes may provide improved anti-hLAG3-based treatment aimed at reawakening #Treg function in #cancer | #immunotherapy #cancerimmunology #ReadTheJI #immunology https://t.co/0AIqes6zvM https://t.co/ZBSidS7tA3
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Mashup Score: 2Therapeutic Effect of Anti-CD52 Monoclonal Antibody in Multiple Sclerosis and Its Animal Models Is Mediated via T Regulatory Cells - 2 year(s) ago
The objective of this study is to determine the mechanism of action of anti-CD52 mAb treatment in patients with relapsing-remitting multiple sclerosis (RRMS). Experimental autoimmune encephalomyelitis (EAE), an animal model of the disease, was used to address the role of T regulatory cells (Tregs)
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
#AuthorChoice: #Alemtuzumab suppresses #EAE via expansion of #Treg cells from Silva Markovic-Plese @TJUHospital #FreetoRead #ReadTheJI #immunology #autoimmunity #immunotherapy #clinicalimmunology https://t.co/nXGSmsmgZm https://t.co/uPiZsade7o
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Mashup Score: 3Current issue: Trends in Immunology - 2 year(s) ago
CD8+ Tregs kill pathogenic cells to avert autoimmunityMouse Ly49+CD8+ regulatory T cells (Tregs) can subdue autoreactive CD4+ T cells to suppress autoimmunity. Recently, Li et al. demonstrated that killer-cell immunoglobulin-like receptor (KIR)+CD8+ T cells are the human equivalent of Ly49+CD8+ regulatory T cells and kill pathogenic CD4+ T cells, which can be increased in certain human…
Source: www.cell.comCategories: Allergy-Immunology, Latest HeadlinesTweet-
@TrendsImmuno June issue! #Zebrafish immuno, #CD8 #Treg, #HIV integration& #nonself genes, #HSC & #transplantation lessons, #SARSCoV2 & #cytokinestorms, #trainedimmunity, #ECM & #cancer, #αfetoprotein, #tRNAs in blood cancers, #lncRNAs in #immunity & more! https://t.co/f4HaqrVNH4 https://t.co/rXFI4mEc2I
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Mashup Score: 0Essential Roles of the Transcription Factor NR4A1 in Regulatory T Cell Differentiation under the Influence of Immunosuppressants - 2 year(s) ago
This article is featured in Top Reads , p.[][1] [1]: /lookup/volpage/208/2079
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
#JI_TopRead from Takehiko Mori @TMDUniversity @NCGM1868 | Essential roles of the #transcriptionfactor NR4A1 in #Treg differentiation under the influence of immunosuppressants #ReadTheJI #immunology #Tcells #GvHD #Transplant https://t.co/H2loyCSOdg https://t.co/z4lbUJzJ1B
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Mashup Score: 3Low Dose IL-2 Therapy in Patients with Chronic Gvhd Induces PD-1+treg That Are Highly Activated, Immune Suppressive, and Proapoptotic - 2 year(s) ago
Journals & BooksRegisterSign inView PDFAccess through your institutionTransplantation and Cellular TherapyVolume 28, Issue 3, Supplement, March 2022, Pages S59-S60Author links open overlay panelShuntaroIkegawaMD, PhDTakeruAsanoMD, PhDHaesook T.KimPhDGordon J.FreemanPhDXiaBuPhDRogerBelizaireMD, PhDJenniferWhangboMD PHDRizwanRomeeMDMahaswetaGooptuMDRoman MShapiroMDSarahNikiforowMD, PhDVincent…
Source: www.sciencedirect.comCategories: Hem/Oncs, Latest HeadlinesTweet-
Low Dose IL-2 Therapy in Patients with Chronic Gvhd Induces PD-1+treg That Are Highly Activated, Immune Suppressive, and Proapoptotic #Tandem22 #IL2 #TReg chronic #GVHD https://t.co/XJ81Xpx4AR
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#ICYMI from Christopher M. Borges @editasmed Method to assess #methylation status and purity of #Treg cells from ex vivo primary human Treg culture #ReadTheJI #immunologicalmethods 👉 https://t.co/l6VyYPdyhv https://t.co/5dSaykLsWg