Wing musculature reconstruction in extinct flightless auks (Pinguinus and Mancalla) reveals incomplete convergence with penguins (Spheniscidae) due to differing ancestral states

Most common cytometry methods, including flow cytometry, observe suspended or fixed cells and cannot evaluate their structural roles in 3D tissues. However, cellular physical interactions…

Spatial and temporal protein tracking in live cells permits proteome remodeling in response to extracellular cues. Historically, protein dynamics during trafficking have been visualized using…

Cryo-EM is a powerful tool in structural biology, providing insights through techniques like single-particle analysis (SPA) and cryogenic electron tomography (cryo-ET). In thick specimens, challenges…

We address the problem of inferring the number of independently blinking fluorescent light emitters, when only their combined intensity contributions can be observed at each…

Clustering of sequences into operational taxonomic units (OTUs) and denoising methods are a mainstream stopgap totaxonomically classifying large numbers of 16S rRNA gene sequences. We…

The advent of droplet-based single-cell RNA-sequencing (scRNA-seq) has dramatically increased data throughput, enabling the release of a diverse array of tissue cell atlases to the…

Unsupervised clustering is a powerful machine-learning technique widely used to analyze high-dimensional biological data. It plays a crucial role in uncovering patterns, structure, and inherent…

Background Substantial discoveries during the past century have revealed that transposable elements (TEs) can play a crucial role in genome evolution by affecting gene expression…