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Mashup Score: 0Top cited articles | BMJ Open Respiratory Research - 11 hour(s) ago
The open access companion journal to Thorax, publishing high quality papers in respiratory medicine, critical care, sleep medicine and related areas.
Source: bmjopenrespres.bmj.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 0Most Read Articles | BMJ Open Respiratory Research - 2 day(s) ago
The open access companion journal to Thorax, publishing high quality papers in respiratory medicine, critical care, sleep medicine and related areas.
Source: bmjopenrespres.bmj.comCategories: General Medicine News, PulmonologyTweet-
We're an open access journal publishing papers across all areas of respiratory medicine, critical care and sleep medicine. Check out our most read articles: https://t.co/Ppk1TZ8QAi #ATS2024 https://t.co/ff4LsZ07yc
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Mashup Score: 7Singing for lung health in COPD: a multicentre randomised controlled trial of online delivery - 16 day(s) ago
Background Singing for lung health (SLH) is an arts-based breathing control and movement intervention for people with long-term respiratory conditions, intended to improve symptoms and quality of life. Online, remotely delivered programmes might improve accessibility; however, no previous studies have assessed the effectiveness of this approach. Methods We conducted an assessor-blind randomised controlled trial comparing the impact of 12 weeks of once-weekly online SLH sessions against usual care on health-related quality of life, assessed using the RAND 36-Item Short Form Health Survey (SF-36) Mental Health Composite (MHC) and Physical Health Composite (PHC) scores. Results We enrolled 115 people with stable chronic obstructive pulmonary disease (COPD), median (IQR) age 69 (62–74), 56.5% females, 80% prior pulmonary rehabilitation, Medical Research Council dyspnoea scale 4 (3–4), forced expiratory volume in 1 s % predicted 49 (35–63). 50 participants in each arm completed the study. T
Source: bmjopenrespres.bmj.comCategories: General Medicine News, PulmonologyTweet-
RT @COPDdoc: Singing for lung health in COPD: a multicentre trial of online delivery https://t.co/eEjD38Wn1Q @BMJOpen_Resp @ThoraxBMJ @Impe…
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Mashup Score: 1
Background There is a lack of knowledge on how patients with asthma or chronic obstructive pulmonary disease (COPD) are globally treated in the real world, especially with regard to the initial pharmacological treatment of newly diagnosed patients and the different treatment trajectories. This knowledge is important to monitor and improve clinical practice. Methods This retrospective cohort study aims to characterise treatments using data from four claims (drug dispensing) and four electronic health record (EHR; drug prescriptions) databases across six countries and three continents, encompassing 1.3 million patients with asthma or COPD. We analysed treatment trajectories at drug class level from first diagnosis and visualised these in sunburst plots. Results In four countries (USA, UK, Spain and the Netherlands), most adults with asthma initiate treatment with short-acting ß2 agonists monotherapy (20.8%–47.4% of first-line treatments). For COPD, the most frequent first-line treatment
Source: bmjopenrespres.bmj.comCategories: General Medicine News, Hem/OncsTweet-
Real-world treatment trajectories of adults with newly diagnosed asthma or COPD https://t.co/xkYac2m6uz via @prieto_alhambra et al
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Mashup Score: 36Systemic corticosteroids in fibrotic lung disease: a systematic review and meta-analysis - 4 month(s) ago
Objectives We aimed to assess the available evidence for corticosteroids in fibrotic interstitial lung disease (fILD) to inform the randomised embedded multifactorial adaptive platform ILD. Design Systematic review and meta-analysis. Data sources We searched Embase, Medline, Cochrane CENTRAL and Web of Science databases from inception to April 17 2023. Eligibility criteria We included studies that compared corticosteroids with standard care, placebo or no treatment in adult patients with fILD. Data extraction and synthesis We report on the change in forced vital capacity (FVC) and mortality. We used random-effects meta-analysis to estimate relative risk (RR) for dichotomous outcomes, and mean difference (MD) and standardised MDs for continuous outcomes, with 95% CIs. Results Of the 13 229 unique citations identified, we included 10 observational studies comprising 1639 patients. Corticosteroids had an uncertain effect on mortality compared with no treatment (RR 1.03 (95% CI 0.85 to 1.2
Source: bmjopenrespres.bmj.comCategories: General Medicine News, PulmonologyTweet-
The current evidence on the efficacy and safety of corticosteroids in fibrotic ILD is limited and of low certainty. Randomised trials are needed to address this significant research gap. @BMJOpen_Resp @IPFdoc https://t.co/lEjWf6sP0F https://t.co/zZuidXguAt
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Mashup Score: 0Chemical exposure and alveolar macrophages responses: ‘the role of pulmonary defense mechanism in inhalation injuries’ - 10 month(s) ago
Epidemiological and clinical studies have indicated an association between particulate matter (PM) exposure and acute and chronic pulmonary inflammation, which may be registered as increased mortality and morbidity. Despite the increasing evidence, the pathophysiology mechanism of these PMs is still not fully characterised. Pulmonary alveolar macrophages (PAMs), as a predominant cell in the lung, play a critically important role in these pathological mechanisms. Toxin exposure triggers events associated with macrophage activation, including oxidative stress, acute damage, tissue disruption, remodelling and fibrosis. Targeting macrophage may potentially be employed to treat these types of lung inflammation without affecting the natural immune response to bacterial infections. Biological toxins, their sources of exposure, physical and other properties, and their effects on the individuals are summarised in this article. Inhaled particulates from air pollution and toxic gases containing c
Source: bmjopenrespres.bmj.comCategories: Latest Headlines, PulmonologyTweet-
Chemical exposure and alveolar macrophages responses: ‘the role of pulmonary defense mechanism in #inhalationinjuries’, read the recently published review here: https://t.co/NBGD3gN4ec https://t.co/Kj4EMQSjFY
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Our journal has a Citescore of 6.4, Impact Factor 4.1, check out our top cited articles: https://t.co/RpQa0vjqQs Including our most cited 'Dysfunctional breathing diagnosed by cardiopulmonary exercise testing in ‘long COVID’ patients with persistent dyspnoea' #ATS2024 https://t.co/AeEI7P7Hsp