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    • Mashup Score: 4
      Multimodal mismatch responses in mouse auditory cortex - 1 month(s) ago

      Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland Faculty of Science, University of Basel, Basel, Switzerland This well-designed study provides important findings concerning the way the brain encodes prediction about self-generated sensory inputs. The authors report that neurons in auditory cortex respond to mismatches in locomotion-driven auditory feedback and that those responses can be enhanced by concurrent mismatches in visual inputs. While there remain alternative explanations

      Source: elifesciences.org
      Categories: General Medicine News, Neurology
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      • Profile photo of 	NeuroscienceNew
        NeuroscienceNew

        “Multimodal mismatch responses in mouse auditory cortex” by Magdalena Solyga et al. eLife https://t.co/TWqN6E5Aj6

    • Mashup Score: 9
      Nocebo effects are stronger and more persistent than placebo effects in healthy individuals - 2 month(s) ago

      Department of Neurology, Center for Translational Neuro- and Behavioral Sciences (C-TNBS), University Medicine Essen, University Duisburg-Essen, Essen, Germany Wellcome Centre for Integrative Neuroimaging (WIN), Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxfor d, United Kingdom In this preregistered study, Kunkel and colleagues set out to compare the magnitude and duration of placebo versus nocebo effects in healthy volunteers, and also to examine the

      Source: elifesciences.org
      Categories: General Medicine News, Neurology
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      • Profile photo of 	NeuroscienceNew
        NeuroscienceNew

        “Nocebo effects are stronger and more persistent than placebo effects in healthy individuals” by Katharina Schmidt et al. eLife https://t.co/zugV50a8XM

    • Mashup Score: 13
      Pyruvate and Related Energetic Metabolites Modulate Resilience Against High Genetic Risk for Glaucoma - 2 month(s) ago

      Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, United States Department of Ophthalmology, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, United States Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, United States Broad Institute of MIT and Harvard, Cambridge, United States NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust, and University College London

      Source: elifesciences.org
      Categories: General Medicine News, Ophthalmology
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      • Profile photo of 	NatEyeInstitute
        NatEyeInstitute

        New #NEIfunded research from @MountSinaiNYC, @UK_Biobank, @HMSEye, and @ColumbiaPS suggests that pyruvate may help lower eye pressure and reduce #glaucoma risk. This could lead to new treatment approaches! Learn more: https://t.co/5v1xKl6KyK #EyeHealth #ResearchNews https://t.co/lPnV4gz4mP

    • Mashup Score: 20
      A single cysteine residue in vimentin regulates long non-coding RNA XIST to suppress epithelial-mesenchymal transition and stemness in breast cancer - 4 month(s) ago

      Centre for Oral Immunobiology and Regenerative Medicine, Institute of Dentistry, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom Department of Oral Biology and Diagnostic Sciences, The Dental College of Georgia, Augusta University, Augusta, United States Georgia Cancer Center, Augusta University, Augusta, United States Centre for Genomics and Child Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary

      Source: elifesciences.org
      Categories: General Medicine News, General HCPs
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      • Profile photo of 	medical_xpress
        medical_xpress

        A single amino acid change in vimentin protein can transform #BreastCancer cells to exhibit stem cell-like behavior, potentially increasing aggressiveness and resistance to treatment. @QMUL @elife https://t.co/lWB6DK4tr1 https://t.co/THq2mBF52Y

    • Mashup Score: 4
      Decreasing human body temperature in the United States since the Industrial Revolution - 5 month(s) ago

      Since the Industrial Revolution, normal body temperature in both men and women has decreased monotonically by 0.03°C per birth decade.

      Source: elifesciences.org
      Categories: General Medicine News, Hem/Oncs
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      • Profile photo of 	nickmmark
        nickmmark

        Here's the study: https://t.co/95coMXByPF

    • Mashup Score: 30
      Chromatin activity of IκBα mediates the exit from naïve pluripotency - 5 month(s) ago

      Program in Cancer Research. Hospital del Mar Research Institute, Barcelona, Spain Josep Carreras Leukemia Research Institute, Barcelona, Spain Centro de Investigación Biomédica en Red Cancer (CIBERONC), Madrid, Spain Institut Investigació Biomèdica de Bellvitge (IDIBELL), L’Hospitalet de Llobregat, Barcelona, Spain Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain Faculty of Sciences, Technology and Engineering, Universitat de Vic – Universitat

      Source: elifesciences.org
      Categories: General Medicine News, Future of Medicine
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      • Profile photo of 	ManelEsteller
        ManelEsteller

        Happy to participate in @eLife publication led by @luigalpal and @BigSpinLab from @HMar_research @CarrerasIJC showing how IκBα, the master regulator of NF-κB signaling, rewires the #chromatin of #stem cells https://t.co/heWZG0uNAs https://t.co/t0LH7nsmyS

    • Mashup Score: 17
      DYRK1A kinase triplication is the major cause of Otitis Media in Down Syndrome - 6 month(s) ago

      Mammalian Genetics Unit, MRC Harwell Institute, Oxford, UK The Francis Crick Institute, London, UK Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, USA Department of Pediatric Otolaryngology, Children’s Hospital Colorado, Aurora, USA Mary Lyon Centre, MRC Harwell Institute, Oxford, UK Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London, UK This study addresses fundamental questions surrounding

      Source: elifesciences.org
      Categories: General Medicine News, General HCPs
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      • Profile photo of 	medical_xpress
        medical_xpress

        A genetic link to #HearingLoss in children with #DownSyndrome has been identified. The Dyrk1a gene, when present in extra copies, is linked to #OtitisMedia with effusion, suggesting new treatment avenues. @uclnews @elife https://t.co/WiunoEWVh9 https://t.co/5Hn8E4ewtR

    • Mashup Score: 4
      Genome concentration limits cell growth and modulates proteome composition in Escherichia coli - 6 month(s) ago

      Genome dilution limits cell growth by modulating the activities, rather than the concentrations, of RNA polymerases and ribosomes, and is accompanied by changes in proteome composition.

      Source: elifesciences.org
      Categories: General Medicine News, Infectious Disease
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      • Profile photo of 	baym
        baym

        RT @jcamthrash: Genome concentration limits cell growth and modulates proteome composition in Escherichia coli https://t.co/XTEYc6DNFX

    • Mashup Score: 5
      A distributed brain response predicting the facial expression of acute nociceptive pain - 7 month(s) ago

      Department of psychology, Université de Montréal, Montreal, Quebec, Canada Centre de recherche de l’institut universitaire de gériatrie de Montréal, Montreal, Quebec, Canada Department of medical psychology and sociology, Medical faculty, University of Augsburg, Augsburg, Germany School of psychology, Université Laval, Quebec, Quebec, Canada Faculty of Dentistry, McGill University, Montreal, Quebec, Canada Department of Anesthesia, McGill University, Montreal, Quebec, Canada Alan Edwards Centre for

      Source: elifesciences.org
      Categories: General Medicine News, Neurology
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      • Profile photo of 	NeuroscienceNew
        NeuroscienceNew

        “A distributed brain response predicting the facial expression of acute nociceptive pain” by Marie-Eve Picard et al. eLife https://t.co/BTEsXFQpQM

    • Mashup Score: 10
      Astrogliosis and neuroinflammation underlie scoliosis upon cilia dysfunction - 7 month(s) ago

      Brain ventricular astrogliosis and neuroinflammation precede scoliosis onset in the zebrafish rpgrip1l ciliary mutant and anti-inflammatory treatment drastically reduces scoliosis while correcting urotensin related peptide level is ineffective.

      Source: elifesciences.org
      Categories: General Medicine News, Hem/Oncs
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      • Profile photo of 	sethcorey
        sethcorey

        RT @eLife: Zebrafish study reveals clues to how inflammation drives scoliosis. https://t.co/soklwcE47x https://t.co/ksEnp0a0J7

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