• Mashup Score: 1

    After cardiac arrest, restoration of circulation is the first step toward survivorship. Extracorporeal CPR (ECPR), the use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) to restore circulation, is increasingly being used in refractory cardiac arrest. The Advanced Reperfusion Strategies for Patients With Out-of-Hospital Cardiac Arrest and Refractory Ventricular Fibrillation (ARREST), Prague Out-of-Hospital, and Early Initiation of Extracorporeal Life Support in Refractory Out-of-Hospital Cardiac Arrest (INCEPTION) randomized controlled trials compared ECPR with conventional CPR for refractory out-of-hospital cardiac arrest (OHCA).

    Tweet Tweets with this article
    • Arterial CO2 Targets in Veno-Arterial Extracorporeal Membrane Oxygenation After Cardiac Arrest - CHEST https://t.co/DkNw4Y2wND #ECMO #CPR #cardiacarrest #HeartAttack

  • Mashup Score: 4

    COPD is a complex, heterogeneous lung disease characterized by persistent airflow limitation secondary to airways and parenchymal abnormalities, and respiratory symptoms, including dyspnea, fatigue, chronic cough, and sputum production. Cigarette smoke exposure is a major contributor to COPD; however, inhalation of toxic particles and other environmental and host factors can contribute to its genesis. Over time, the clinical course is frequently punctuated by exacerbations that further accelerate lung function decline and increase exacerbation risk.

    Tweet Tweets with this article
    • The Emerging Role of Alarmin-Targeting Biologics in the Treatment of Patients With COPD https://t.co/3KAug2inKF via @Hananianick et al https://t.co/HwKvtYFzr7

  • Mashup Score: 6

    Asthma is a common, multifaceted respiratory disease with a major impact on quality of life. Despite increased insights into mechanisms underlying various asthma phenotypes and endotypes and the availability of targeted biologic treatment options, the disease remains uncontrolled in a substantial proportion of patients with risk of exacerbations, requiring systemic corticosteroids, and with progressive disease. Current international guidelines advocate for a personalized management approach to patients with uncontrolled severe asthma.

    Tweet Tweets with this article
    • RT @Hananianick: Promoting Prevention and Targeting Remission of Asthma - CHEST https://t.co/wqXauwXiNO @BCMCME @BCM_Lung @BCMLungInst