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Mashup Score: 28Verrucous plaque on the face - 2 month(s) ago
A healthy, Hispanic, 23-year-old woman living in Illinois, presented with 10-month history of a verrucous plaque on the left lower face. She had been treated for a pneumonia just prior to the plaque developing. The patient stated the lesion had started as a “pimple” and has continued to enlarge. Treatment with over-the-counter triple antibiotic ointment and hydrocortisone cream yielded no improvement. Over the next 10 months, the lesion continued to grow and she ultimately sought medical care. Physical exam revealed a 12-cm plaque on the L lower cheek and neck with central crusting, erosions, and a verrucous, hyperkeratotic border; no other lesions or salient physical findings were otherwise present.
Source: www.jaadcasereports.orgCategories: General Medicine News, DermatologyTweet
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Mashup Score: 18Verrucous plaque on the face - 3 month(s) ago
A healthy, Hispanic, 23-year-old woman living in Illinois, presented with 10-month history of a verrucous plaque on the left lower face. She had been treated for a pneumonia just prior to the plaque developing. The patient stated the lesion had started as a “pimple” and has continued to enlarge. Treatment with over-the-counter triple antibiotic ointment and hydrocortisone cream yielded no improvement. Over the next 10 months, the lesion continued to grow and she ultimately sought medical care. Physical exam revealed a 12-cm plaque on the L lower cheek and neck with central crusting, erosions, and a verrucous, hyperkeratotic border; no other lesions or salient physical findings were otherwise present.
Source: www.jaadcasereports.orgCategories: General Medicine News, DermatologyTweet
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Mashup Score: 19Nodules and ulcerations on back, scalp, axillae, and buttocks - 3 month(s) ago
A 62-year-old African American male with SLE presented with a six-year history of worsening recurrent bumps and open sores on the scalp, back, and axillae. He reported multiple emergency department and urgent care visits as well as several treatments with no improvement. Physical examination of the scalp, face, trunk, axillae, and buttocks revealed numerous papules and nodules, some of which were ulcerated (Figs 1 and 2). Biopsies of the scalp and back revealed nodular and diffuse dermal infiltrate with a mixed population of cells with large reniform nuclei, lymphocytes, plasma cells, and eosinophils in fibrosing granulation tissue (Fig 3).
Source: www.jaadcasereports.orgCategories: General Medicine News, DermatologyTweet
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Mashup Score: 16Painful plaques in a woman with recurrent squamous cell carcinoma - 4 month(s) ago
A 79-year-old woman with an elevated body mass index presented with a painful, pruritic, tender plaque on her inferior abdomen, extending to her superior mons pubis and progressing to her right lateral thigh, intermittently recurring with rigors and night sweats for over 6 years (Fig 1). She had a history of vulvar squamous cell carcinoma and vulvar lichen sclerosus since 2013 and was awaiting re-excision for her third squamous cell carcinoma recurrence. None of her medications had been dose-adjusted or introduced within this time frame.
Source: www.jaadcasereports.orgCategories: General Medicine News, DermatologyTweet-
What's the #diagnosis? 79-year-old woman with elevated body mass index presented with a painful, pruritic, tender plaque on her inferior abdomen, extending to her superior mons pubis and progressing to her right lateral thigh, intermittently recurring... https://t.co/zLSKiAZtIE https://t.co/RzUlawuF6g
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Mashup Score: 20Reddish plaque and nodules on a child's cheek - 4 month(s) ago
A 14-year-old child, operated on; at the age of 5; for dacryocystitis secondary to a trauma of the right eye. He has since presented a recurrent periorbital erythema treated several times as eczema by topic corticosteroids without improvement. The evolution was marked, 9 years later, by the extension of the erythematous plaque to the cheek and nose, appearance of lupoid nodules and keratinization of the appendages of the eye with ectropion (Fig 1). Dermoscopy showed yellow-orange globules, white scales, branching and dot vessels, and white structureless areas (Fig 2).
Source: www.jaadcasereports.orgCategories: General Medicine News, Partners & KOLsTweet-
What's the #diagnosis? A 14-year-old was operated on at the age of 5 for dacryocystitis secondary to a trauma of the right eye. He has since presented a recurrent periorbital erythema that was treated several times as eczema by topical corticosteroids... https://t.co/4qQvBw3Xk1 https://t.co/qnm6moz8ml
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Mashup Score: 16Evolving mucocutaneous eruptions following chemotherapy - 4 month(s) ago
A 62-year-old male with follicular lymphoma presented with a 3-week history of worsening erythematous, coalescing papules and plaques with desquamative scale, and oral mucosa erosions starting 4 days after receiving rituximab, bendamustine, trimethoprim/sulfamethoxazole, and allopurinol (Fig 1, A-C). There was no improvement after holding medications, oral prednisone, and topical steroids. Biopsy of the dorsal hand was performed (Fig 2). Within 2 weeks, the rash progressed to erythroderma with erosions and hemorrhagic crusting of mucosal sites and diffusely on the body (Fig 3, A-C).
Source: www.jaadcasereports.orgCategories: General Medicine News, DermatologyTweet-
What's the #diagnosis? ➡️ A 62-year-old male with follicular lymphoma presented with a 3-week history of worsening erythematous, coalescing papules and plaques with desquamative scale, and oral mucosa erosions starting 4 days after receiving rituximab... https://t.co/g1hGA8f8IP https://t.co/lF5QyygRM9
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Mashup Score: 17
Hypereosinophilic syndrome (HES) is characterized by persistent eosinophilia in the blood or peripheral tissues, organ damage and/or dysfunction attributable to tissue hypereosinophilia, and exclusion of other disorders or conditions as the major reason for organ damage. The cutaneous and histologic manifestations of HES are variable and include psoriasiform dermatitis, urticaria, angioedema, atopic dermatitis, and erythroderma.1 Here, we report 2 cases of HES that presented with variable skin and biopsy findings.
Source: www.jaadcasereports.orgCategories: General Medicine News, Partners & KOLsTweet-
A 67-year-old man presented with a 2-month history of diffuse, itchy #rash involving the scalp, face, arms, and trunk, characterized by widespread pink-to-brown, small, round-to-oval, thin papules with overlying scale. Biopsy showed regular psoriasiform... https://t.co/VQLMcUClyb https://t.co/a8J40GnYRA
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Mashup Score: 4Line-field confocal optical coherence tomography imaging findings of scalp psoriasis - 5 month(s) ago
A 64-year-old woman presented to the clinic with two pink, scaly plaques with excoriations on the right side of the temple and the left side of the abdomen. The initial clinical suspicion was eczema, and the patient was instructed to apply hydrocortisone 2.5% cream to the area. There was no resolution after 2 months of treatment, and the patient was imaged with line-field confocal optical coherence tomography (LC-OCT), and a shave tangential biopsy was also performed (Fig 1).
Source: www.jaadcasereports.orgCategories: General Medicine News, Partners & KOLsTweet-
A 64-year-old woman presented to the clinic with two pink, scaly plaques with excoriations on the right side of the temple and the left side of the abdomen. The initial clinical suspicion was eczema, and the patient was instructed to apply hydrocortisone...https://t.co/CKHgClX9Au https://t.co/Rs2evHvqmg
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Mashup Score: 17Evolving mucocutaneous eruptions following chemotherapy - 6 month(s) ago
A 62-year-old male with follicular lymphoma presented with a 3-week history of worsening erythematous, coalescing papules and plaques with desquamative scale, and oral mucosa erosions starting 4 days after receiving rituximab, bendamustine, trimethoprim/sulfamethoxazole, and allopurinol (Fig 1, A-C). There was no improvement after holding medications, oral prednisone, and topical steroids. Biopsy of the dorsal hand was performed (Fig 2). Within 2 weeks, the rash progressed to erythroderma with erosions and hemorrhagic crusting of mucosal sites and diffusely on the body (Fig 3, A-C).
Source: www.jaadcasereports.orgCategories: General Medicine News, DermatologyTweet-
What's the #diagnosis? ➡️ A 62-year-old male with follicular lymphoma presented with a 3-week history of worsening erythematous, coalescing papules and plaques with desquamative scale, and oral mucosa erosions starting 4 days after receiving rituximab... https://t.co/g1hGA8f8IP https://t.co/lF5QyygRM9
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Mashup Score: 43Multifocal lesions of the lungs, skin, bones, and brain - 6 month(s) ago
A previously healthy 34-year-old male from Minnesota presented with acute right hip and shoulder pain. He had a 5-month history of scattered violaceous cutaneous nodules involving his face, trunk, and extremities (Fig 1), accompanied by cough and headaches. HIV testing was negative. Chest X-ray revealed a left upper lobe lung infiltrate. Magnetic resonance imaging of the right shoulder showed cortical bone destruction (Fig 2, A). Brain magnetic resonance imaging demonstrated pachymeningeal enhancement (Fig 2, B), and positron-emission tomography/computed tomography (PET/CT) (Fig 2, C) used to determine the extent of disease revealed involvement of subcutaneous tissues, lungs, and bones (Fig 2, B).
Source: www.jaadcasereports.orgCategories: General Medicine News, Partners & KOLsTweet
What is the #diagnosis? A healthy 23-year-old Hispanic woman from Illinois presented with a 10-month history of a verrucous plaque on the left lower face. She had been treated for a pneumonia just prior to the plaque developing. @jaadjournals https://t.co/FfOG20HmjK https://t.co/qICXAvL0xZ