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Mashup Score: 12
Vol. 21 Issue 12 p3304 – 3316 Nicola J. Mutch Robert L. Medcalf Fibrinolysis is the system primarily responsible for removal of fibrin deposits and blood clots in the vasculature. The terminal enzyme in the pathway, plasmin, is formed from its circulating precursor, plasminogen. Fibrin is by far the most legendary substrate, but plasmin is notoriously prolific and is known to cleave many other proteins and participate in the activation of other proteolytic systems. Fibrinolysis is often overshadowed by
Source: www.jthjournal.orgCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 63Hormonal contraceptive use after a first venous thrombotic event and the risk of recurrence in premenopausal women - 6 day(s) ago
Extensive evidence is available on hormonal contraceptive (HC) use and the risk of a first venous thromboembolism (VTE) event. Despite recommendations to discontinue combined HC (CHC) use, some women continue or start its use after a first VTE.
Source: www.jthjournal.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 6Management of Abnormal Uterine Bleeding on Anticoagulation: The Patient-Clinician Perspective - 10 day(s) ago
Bleeding is a well-recognized side effect of anticoagulant therapy, which is used to treat venous thromboembolism (VTE) in individuals of all ages, including those of female sex, who commonly experience VTE as a complication of hormonal therapies and/or pregnancy. Heavy menstrual bleeding (HMB) is also extremely common in reproductive aged individuals of female sex. Despite these overlapping situations, relatively little attention has been paid to the impact of anticoagulant-associated HMB on treatment strategies and the patient experience.
Source: www.jthjournal.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 6Management of Abnormal Uterine Bleeding on Anticoagulation: The Patient-Clinician Perspective - 10 day(s) ago
Bleeding is a well-recognized side effect of anticoagulant therapy, which is used to treat venous thromboembolism (VTE) in individuals of all ages, including those of female sex, who commonly experience VTE as a complication of hormonal therapies and/or pregnancy. Heavy menstrual bleeding (HMB) is also extremely common in reproductive aged individuals of female sex. Despite these overlapping situations, relatively little attention has been paid to the impact of anticoagulant-associated HMB on treatment strategies and the patient experience.
Source: www.jthjournal.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 12
Vol. 21 Issue 12 p3304 – 3316 Nicola J. Mutch Robert L. Medcalf Fibrinolysis is the system primarily responsible for removal of fibrin deposits and blood clots in the vasculature. The terminal enzyme in the pathway, plasmin, is formed from its circulating precursor, plasminogen. Fibrin is by far the most legendary substrate, but plasmin is notoriously prolific and is known to cleave many other proteins and participate in the activation of other proteolytic systems. Fibrinolysis is often overshadowed by
Source: www.jthjournal.orgCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 2Availability of medical and endovascular therapies for venous thromboembolism: a global survey for World Thrombosis Day - 18 day(s) ago
Data on availability, affordability, and accessibility is key for the planning of global strategies to reduce the burden of venous thromboembolism (VTE).
Source: www.jthjournal.orgCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 20Standardisation of Definition and Management for Bleeding Disorder of Unknown Cause: Communication from the SSC of the ISTH. - 20 day(s) ago
In many patients referred with significant bleeding phenotype, laboratory testing fails to define any hemostatic abnormalities. Clinical practise with respect to diagnosis and management of this patient cohort poses significant clinical challenges. We recommend that bleeding history in these patients should be objectively assessed using the ISTH bleeding assessment tool (BAT). Patients with increased BAT scores should progress to hemostasis laboratory testing. To diagnose BDUC, normal complete blood count, prothrombin time, activated partial thromboplastin time, thrombin time, von Willebrand factor antigen, von Willebrand factor function; coagulation factors VIII, IX and XI and platelet light transmission aggregometry (LTA) should be the minimum laboratory assessment.
Source: www.jthjournal.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 33Low-dose emicizumab prophylaxis in patients with severe hemophilia A: a retrospective study bringing new hope for our patients - 1 month(s) ago
Low-dose emicizumab can potentially offer a cost-effective treatment option in persons with hemophilia A, especially in developing countries.
Source: www.jthjournal.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 12
Vol. 21 Issue 12 p3304 – 3316 Nicola J. Mutch Robert L. Medcalf Fibrinolysis is the system primarily responsible for removal of fibrin deposits and blood clots in the vasculature. The terminal enzyme in the pathway, plasmin, is formed from its circulating precursor, plasminogen. Fibrin is by far the most legendary substrate, but plasmin is notoriously prolific and is known to cleave many other proteins and participate in the activation of other proteolytic systems. Fibrinolysis is often overshadowed by
Source: www.jthjournal.orgCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 12
Vol. 21 Issue 12 p3304 – 3316 Nicola J. Mutch Robert L. Medcalf Fibrinolysis is the system primarily responsible for removal of fibrin deposits and blood clots in the vasculature. The terminal enzyme in the pathway, plasmin, is formed from its circulating precursor, plasminogen. Fibrin is by far the most legendary substrate, but plasmin is notoriously prolific and is known to cleave many other proteins and participate in the activation of other proteolytic systems. Fibrinolysis is often overshadowed by
Source: www.jthjournal.orgCategories: General Medicine News, Onc News and JournalsTweet
Read this special collection of review articles honoring the 20th anniversary of the Journal of Thrombosis and Haemostasis. An impressive collection of reviews from world-renowned experts on some of the most important topics in the field. https://t.co/4dm2L4hjWJ @JTHjournal https://t.co/iQsOR6UVNk