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Mashup Score: 15Evidence of Diplopia in Children's Headache Drawings Helps to Differentiate Pseudotumor Cerebri From Migraine - 2 day(s) ago
This study aimed to determine whether children’s headache drawings can distinguish between pseudotumor cerebri and migraine.
Source: www.pedneur.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 4Practical considerations for delandistrogene moxeparvovec gene therapy in patients with Duchenne muscular dystrophy - 2 month(s) ago
Delandistrogene moxeparvovec is a gene transfer therapy approved in the United States, United Arab Emirates, and Qatar for the treatment of ambulatory patients aged 4 through 5 years with a confirmed Duchenne muscular dystrophy (DMD)-causing mutation in the DMD gene. It was developed to address the underlying cause of DMD through targeted skeletal, respiratory, and cardiac muscle expression of delandistrogene moxeparvovec micro-dystrophin, an engineered, functional dystrophin protein. Drawing on clinical trial experience from Study 101 (NCT03375164), Study 102 (NCT03769116), and ENDEAVOR (Study 103; NCT04626674), we outline practical considerations for delandistrogene moxeparvovec treatment.
Source: www.pedneur.comCategories: General Medicine News, Hem/OncsTweet-
RT @LakhotiaNeuro: Nice review paper of practical considerations for gene replacement therapy for #DMD - https://t.co/Ma9gzFODH4 #OpenA…
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Mashup Score: 0Pediatric Neurology in the Post-Roe Era - 3 month(s) ago
Dismantling the precedent previously established by Roe v Wade has had far-reaching consequences. Since the Supreme Court’s ruling in Dobbs v Jackson Women’s Health Organization, abortion bans or restrictions have been enacted across half of the country.1,2 The purpose of this editorial is to discuss the practical implications of the Dobbs decision for pediatric neurologists, our patients, and their families/caregivers. As a microcosm of our polarized society, the pediatric neurology community likely contains a multitude of views on abortion and its regulation.
Source: www.pedneur.comCategories: General Medicine News, Hem/OncsTweet-
Here’s our opinion on how pediatric neurologists and our patients will suffer in the post-Roe era. @pedneurojournal @AgSonika @ChildrensPhila Dr. Dawn Gano. @UCSFChildrens @MSKCancerCenter https://t.co/Rx4ybWUMcy
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Mashup Score: 35Leptomeningeal enhancement in pediatric MOG antibody disease, multiple sclerosis, and NMOSD - 3 month(s) ago
Anti-myelin oligodendrocyte glycoprotein (MOG) antibody disease (MOGAD) is a type of acquired demyelinating disease that is distinct from multiple sclerosis (MS) and aquaporin-4 antibody neuromyelitis optica spectrum disorder (AQP4-NMOSD). Leptomeningeal enhancement (LME) has been reported in children and adults with MOGAD, and in adults with MS and AQP4-NMOSD, but less is known about LME in pediatric-onset MS (POMS) and pediatric AQP4-NMOSD. Here we compare rates of LME in children with MOGAD, POMS, and AQP4-NMOSD.
Source: www.pedneur.comCategories: General Medicine News, Hem/OncsTweet-
📣 Hot off the press! @pedneurojournal @GraceGombolayMD and colleagues. Click link below for the full story! @ChildNeuroSoc @AANmember Leptomeningeal enhancement in pediatric MOG antibody disease, multiple sclerosis, and NMOSD - Pediatric Neurology https://t.co/S8t8XSvf2r
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Mashup Score: 5The Association of Therapeutic Hypothermia With Seizure Burden in Neonates With Hypoxic-Ischemic Encephalopathy - 4 month(s) ago
To compare seizure burden between newborn infants treated with therapeutic hypothermia (TH) and those that were not and to compare the need for antiseizure medications (ASM) in a cohort of infants who were diagnosed with neonatal hypoxic-ischemic encephalopathy (HIE).
Source: www.pedneur.comCategories: General Medicine News, NeurologyTweet-
RT @pedneurojournal: Association of therapeutic hypothermia w/seizure burden in neonates with #HIE https://t.co/XVR6462ibr - TH associate…
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Mashup Score: 1Review of Machine Learning and Artificial Intelligence (ML/AI) for the Pediatric Neurologist - 5 month(s) ago
Artificial intelligence (AI) and a popular branch of AI known as machine learning (ML) are increasingly being utilized in medicine and to inform medical research. This review provides an overview of AI and ML (AI/ML), including definitions of common terms. We discuss the history of AI and provide instances of how AI/ML can be applied to pediatric neurology. Examples include imaging in neuro-oncology, autism diagnosis, diagnosis from charts, epilepsy, cerebral palsy, and neonatal neurology. Topics such as supervised learning, unsupervised learning, and reinforcement learning are discussed.
Source: www.pedneur.comCategories: General Medicine News, Hem/OncsTweet-
RT @pedneurojournal: Read the article here -- https://t.co/EqFC5uJGjn #MachineLearning #ArtificialIntelligence #ChildNeurology
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Mashup Score: 2
Neonatal seizures, one of the main risk factors for the development of epilepsy, remain a clinical concern. In children with neonatal seizures, early recognition of risk factors is important for the early diagnosis and appropriate treatment of epilepsy and for improving prognosis. In this study, we aimed to determine the frequency of and the risk factors for the development of epilepsy in patients with neonatal seizures.
Source: www.pedneur.comCategories: General Medicine News, Hem/OncsTweet-
RT @pedneurojournal: Epilepsy Frequency and Risk Factors Three Years After Neonatal Seizures - https://t.co/XYomkb4tlO 👶Neonatal seizures…
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Mashup Score: 3
Acute flaccid myelitis (AFM) presents with acute onset of flaccid paralysis with involvement of the gray matter on magnetic resonance imaging (MRI) of the spinal cord. Studies have reported brain MRI abnormalities, but the characteristics have not been fully defined. In this multicenter study, we assessed the acute features and evolution of brain MRI abnormalities in AFM.
Source: www.pedneur.comCategories: General Medicine News, Hem/OncsTweet-
RT @pedneurojournal: This paper explores brain imaging abnormalities in AFM - https://t.co/C6Z2rvEPTz - Can be seen in ~50% of AFM cases!…
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Mashup Score: 0Neonatal Botulism: A Case Series Suggesting Varied Presentations - 9 month(s) ago
Infantile botulism is an uncommon diagnosis and rarer still in the neonatal period. We describe three cases of neonatal-onset botulism that presented with symptoms typically (hypotonia, constipation, facial diplegia) or atypically seen in older infants (encephalopathy, seizures, and hypothermia). Our series shows a wider spectrum of clinical presentations in patients with neonatal-onset botulism. Our report also suggests that neonatal-onset botulism should be considered more broadly in the hypotonic infant, especially as the condition is treatable with intravenous botulinum-specific immune globulin.
Source: www.pedneur.comCategories: Hem/Oncs, Latest HeadlinesTweet-
RT @pedneurojournal: 👏👏This paper is also this month’s pick for the Editor’s choice article! 👏👏 Read it here: https://t.co/JIXng97TYR htt…
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Mashup Score: 2Current Issue Table of Contents: Pediatric Neurology - 1 year(s) ago
Clinical ObservationsSARS-CoV-2-Related Acute Necrotizing Encephalopathy of Childhood With Good Response to Tocilizumab in an AdolescentJasmine H.Y. Ho,Cheryl Y.M. Lee,Yee Keow Chiong,…Li Jia Fan,Amos H.S. Tan,Velda X. HanPublished online: November 25, 2022p65-69Full-Text HTMLPDF Clinical LetterParoxysmal Tonic Upgaze in a Patient With Congenital Ataxia due to a De Novo Missense…
Source: www.pedneur.comCategories: Hem/Oncs, Latest HeadlinesTweet-
RT @pedneurojournal: Happy New Year! See the Jan 2023 issue: https://t.co/K8DeB3k1ER https://t.co/m6ru0s0tq1
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Young children may have a hard time articulating details of their headache. This is where a little creativity can help ⬇️ Asking children to draw their headaches can provide important diagnostic clues (Image from https://t.co/nNQZbgARkm) https://t.co/EO5qt8cM7n