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Mashup Score: 230
Avian influenza (serotype H5N1) is a highly pathogenic virus that emerged in domestic waterfowl in 1996. Over the past decade, zoonotic transmission to mammals, including humans, has been reported. Although human to human transmission is rare, infection has been fatal in nearly half of patients who have contracted the virus in past outbreaks. The increasing presence of the virus in domesticated animals raises substantial concerns that viral adaptation to immunologically naive humans may result in the next flu pandemic. Wastewater-based epidemiology (WBE) to track viruses was historically used to track polio and has recently been implemented for SARS-CoV2 monitoring during the COVID-19 pandemic. Here, using an agnostic, hybrid-capture sequencing approach, we report the detection of H5N1 in wastewater in nine Texas cities, with a total catchment area population in the millions, over a two-month period from March 4th to April 25th, 2024. Sequencing reads uniquely aligning to H5N1 covered
Source: www.medrxiv.orgCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 230
Avian influenza (serotype H5N1) is a highly pathogenic virus that emerged in domestic waterfowl in 1996. Over the past decade, zoonotic transmission to mammals, including humans, has been reported. Although human to human transmission is rare, infection has been fatal in nearly half of patients who have contracted the virus in past outbreaks. The increasing presence of the virus in domesticated animals raises substantial concerns that viral adaptation to immunologically naive humans may result in the next flu pandemic. Wastewater-based epidemiology (WBE) to track viruses was historically used to track polio and has recently been implemented for SARS-CoV2 monitoring during the COVID-19 pandemic. Here, using an agnostic, hybrid-capture sequencing approach, we report the detection of H5N1 in wastewater in nine Texas cities, with a total catchment area population in the millions, over a two-month period from March 4th to April 25th, 2024. Sequencing reads uniquely aligning to H5N1 covered
Source: www.medrxiv.orgCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 24
J.D. Power released its annual North America Airline Satisfaction Survey for 2024.
Source: www.thestreet.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 283Bird flu in US cows: where will it end? - 6 day(s) ago
Nature – Scientists worry that the H5N1 strain of avian influenza will become endemic in cattle, which would facilitate its spread in people.
Source: www.nature.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 549Emergence and interstate spread of highly pathogenic avian influenza A(H5N1) in dairy cattle - 12 day(s) ago
Highly pathogenic avian influenza (HPAI) viruses cross species barriers and have the potential to cause pandemics. In North America, HPAI A(H5N1) viruses related to the goose/Guangdong 2.3.4.4b hemagglutinin phylogenetic clade have infected wild birds, poultry, and mammals. Our genomic analysis and epidemiological investigation showed that a reassortment event in wild bird populations preceded a single wild bird-to-cattle transmission episode. The movement of asymptomatic cattle has likely played a role in the spread of HPAI within the United States dairy herd. Some molecular markers in virus populations were detected at low frequency that may lead to changes in transmission efficiency and phenotype after evolution in dairy cattle. Continued transmission of H5N1 HPAI within dairy cattle increases the risk for infection and subsequent spread of the virus to human populations. ### Competing Interest Statement The authors have declared no competing interest.
Source: www.biorxiv.orgCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 134Note about availability of H5N1 2.3.4.4b consensus sequences from cattle and other species: - 16 day(s) ago
On Sunday, April 21st, 2024, “in the interest of public transparency and ensuring the scientific community has access to this information as quickly as possible to encourage disease research and development to benefit the U.S. dairy industry”, the National Veterinary Services Laboratories (NVSL) of the Animal and Plant Health Inspection Service (APHIS) of the U.S. Department of Agriculture (USDA) shared H5N1 sequence reads from 239 Biosamples related to the ongoing H5N1 clade 2.3.4.4b influenza …
Source: virological.orgCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 143
I normally don’t publish email exchanges, but when someone like Paul Thacker misleadingly characterizes one with me, I make an exception.
Source: www.respectfulinsolence.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 4Dog dies after contracting avian flu in Oshawa - 1 month(s) ago
The Canadian Food Inspection Agency says the number of documented cases of H5N1 — also known as avian flu — in other species like cats and dogs is low, and based on current evidence, the risk to the general public remains low. (Maryse Zeidler/CBC) A pet dog in Oshawa has died after testing positive for avian flu, the Canadian Food Inspection Agency (CFIA) says. In a news release issued Tuesday, the agency said the dog was infected and died last week after chewing on a wild goose. The CFIA says the number
Source: www.cbc.caCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 10Now that bird flu is spreading among cows, scientists worry where H5N1 will jump next - 1 month(s) ago
Just days after early reports of sick cows at several U.S. farms, H5N1 bird flu has been identified in at least a dozen herds across six states. Scientists are on high alert. But many say what worries them more is whether this virus will jump to more livestock — and pigs, in particular. (Ohio Department of Agriculture) On March 25, American officials published an urgent announcement: Dairy cows in Texas, Kansas, and New Mexico were falling sick. The cows had low appetites, and produced less milk than
Source: www.cbc.caCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 47The Deaths of Effective Altruism - 2 month(s) ago
Sam Bankman-Fried is finally facing punishment. Let’s also put his ruinous philosophy on trial.
Source: www.wired.comCategories: General Medicine News, Infectious DiseaseTweet
It’s clear that much more surveillance is needed. Detection of H5N1 in wastewater is a great demonstration of how every extra piece of information is helpful. If we want to finish the puzzle, we need every piece. https://t.co/ExXhkdV9Xp