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Mashup Score: 1
Editorial 75th anniversary of the British Journal of…
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 1
Cigarette smoking is the main risk factor for head and neck cancer (HNC) and many HNC patients are active smokers at diagnosis. We conducted a systematic literature review and meta-analysis to quantify the survival impact of smoking cessation at or around the time of HNC diagnosis. We searched studies published until December 31, 2021, and used random-effects meta-analysis to pool study-specific…
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 1Digital Imaging - 2 year(s) ago
BJC’s Digital Imaging series is open to receiving submissions assessing: State-of-the-art in digital imaging technology and computational output; …
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Liquid Biopsy - 2 year(s) ago
In recent years we have seen continued growth in the field of precision medicine. Developments in technology have yielded the ability to detect many …
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 2A novel circulating miRNA panel for non-invasive ovarian cancer diagnosis and prognosis - British Journal of Cancer - 2 year(s) ago
Ovarian cancer (OC) is an aggressive disease, primarily diagnosed in late stages with only 20% of patients surviving more than 5 years after diagnosis. There is a pending need to improve current diagnostics and prognostics. In this study, we investigated total circulating cell-free microRNA (cf-miRNA) levels as well as a panel of cf-miRNAs in the plasma of OC patients (n = 100), patients with…
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Journal News | British Journal of Cancer - 2 year(s) ago
Journal News
Source: www.nature.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 4Inhibition of PFKFB3 in HER2-positive gastric cancer improves sensitivity to trastuzumab by inducing tumour vessel normalisation - 2 year(s) ago
Multiple mechanisms have been proposed that lead to reduced effectiveness of trastuzumab in HER2-positive gastric cancer (GC), yet resistance to trastuzumab remains a challenge in clinics. We established trastuzumab-resistant cells and patient-derived xenografts models to measure metabolic levels and vascular density and shape. The HER2-positive GC patient samples were used to determine clinical…
Source: www.nature.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 3
Colorectal cancer (CRC) is prevalent worldwide and is often challenged by treatment failure and recurrence due to resistance to radiotherapy. Here, we aimed to identify the elusive underlying molecular mechanisms of radioresistance in CRC. Weighted gene co-expression network analysis was used to identify potential radiation-related genes. Colony formation and comet assays and multi-target…
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
POH1/Rpn11/PSMD14 is a highly conserved protein in eukaryotes from unicellular organisms to human and has a crucial role in cellular homoeostasis. It is a subunit of the regulatory particle of the proteasome, where it acts as an intrinsic deubiquitinase removing polyubiquitin chains from substrate proteins. This function is not only coupled to the translocation of substrates into the core of the…
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0HIF-1α stimulates the progression of oesophageal squamous cell carcinoma by activating the Wnt/β-catenin signalling pathway - 2 year(s) ago
This study aimed to clarify the significance of the crosstalk between hypoxia-inducible factor-1α (HIF-1α) and the Wnt/β-catenin pathway in oesophageal squamous cell carcinoma (ESCC). The oncogenic role of HIF-1α in ESCC was investigated using in vitro and in vivo assays. The clinicopathological significance of HIF-1α, β-catenin and TCF4/TCF7L2 in ESCC were evaluated using quantitative real-time…
Source: www.nature.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
Commissioned to celebrate 75 years of the BJC, this special issue looks back on some of the most impactful publications from the journal's long history. The original authors and leading experts giving an overview of the field and important key lessons: https://t.co/gJ1rcK8w0d https://t.co/QNTO8TDQtS