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Mashup Score: 3Amyloidosis and Amyloidogenesis - 19 hour(s) ago
Amyloidosis is a heterogenous group of disorders, caused by the deposition of insoluble fibrils derived from misfolded proteins in the extracellular space of various organs. These proteins have an unstable structure that causes them to misfold, aggregate, and deposit as amyloid fibrils with the pathognomonic histologic property of green birefringence when viewed under cross-polarized light after staining with Congo red. Amyloid fibrils are insoluble and degradation-resistant; resistance to catabolism results in progressive tissue amyloid accumulation. The outcome of this process is organ disfunction independently from the type of deposited protein, however there can be organ that are specifically targeted from certain proteins.
Source: www.heartfailure.theclinics.comCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 4Management of arrythmias during pregnancy - 6 day(s) ago
### Learning objectives A sensation of abnormal or irregular heart beating is a very common symptom in pregnancy. This is often secondary to sinus tachycardia, sinus bradycardia and sinus arrhythmia, or isolated premature atrial or ventricular arrhythmias (VAs). The overall incidence of arrhythmia documented in pregnancy is reported to be in the range of 0.03%–0.5% of pregnancies,1 making this one of the most common cardiac complications of pregnancy, in women with and without structural heart disease.2–4 The incidence of arrhythmia in pregnancy is increasing, a rise attributable to the increase in the proportion of women with structural heart disease achieving successful pregnancies in the last decade.5 Clinical evaluation of the symptomatic pregnant patient begins with a careful history, detailing the timing of onset of symptoms, frequency and potential exacerbating factors. A careful family history, probing for a history of unexplained sudden death, heart failure, cardiac transplant
Source: heart.bmj.comCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 1Mitral Annular Disjunction in the Context of Mitral Valve Prolapse: Identifying the At-Risk Patient - 6 day(s) ago
AbstractMitral annular disjunction (MAD), a separation between the left atrium/mitral valve annulus and the left ventricular myocardium, is frequently seen in patients with arrhythmic mitral valve …
Source: www.jacc.orgCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 2Prognostic Value of a 6-Minute Walk Test in Patients With Transthyretin Cardiac Amyloidosis: - 7 day(s) ago
AbstractBackgroundThe 6-minute walk test (6MWT) represents a comprehensive functional assessment that is commonly used in patients with heart failure; however, data are lacking in patients with tra…
Source: www.jacc.orgCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 2Prognostic Value of a 6-Minute Walk Test in Patients With Transthyretin Cardiac Amyloidosis: - 7 day(s) ago
AbstractBackgroundThe 6-minute walk test (6MWT) represents a comprehensive functional assessment that is commonly used in patients with heart failure; however, data are lacking in patients with tra…
Source: www.jacc.orgCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 8
The acute aortic syndromes (AAS) are life-threatening vascular compromises within the aortic wall. These include aortic dissection (AD), intramural hematoma (IMH), penetrating aortic ulcer (PAU), and blunt traumatic thoracic aortic injury (BTTAI). While patients classically present with chest pain, the presentation may be highly variable. Timely diagnosis is critical to initiate definitive treatment and maximize chances of survival. In high-risk patients, treatment should begin immediately, even while diagnostic evaluation proceeds. The mainstay of medical therapy is acute reduction of heart rate and blood pressure. Surgical intervention is often required but is informed by patient anatomy and extent of vascular compromise.
Source: www.cardiology.theclinics.comCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 77Valvulopatías agudas: Cómo afrontar la emergencia - 11 day(s) ago
El reconocimiento rápido de las lesiones valvulares agudas graves es esencial porque el colapso hemodinámico puede producirse rápidamente.
Source: www.cardioteca.comCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 1Normal-Flow Low-Gradient Aortic Stenosis: Comparing the U.S. and European Guidelines - 11 day(s) ago
AbstractPatients with normal-flow low-gradient (NFLG) severe aortic stenosis present both diagnostic and management challenges, with debate about the whether this represents true severe stenosis an…
Source: www.jacc.orgCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 8Non-invasive imaging in acute decompensated heart failure with preserved ejection fraction - 13 day(s) ago
Abstract. Non-invasive imaging plays an increasingly important role in emergency medicine, given the trend towards smaller, portable ultrasound devices, th
Source: academic.oup.comCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 5Magnetic Resonance Imaging Characterization and Clinical Outcomes of Dilated and Arrhythmogenic Left Ventricular Cardiomyopathies: - 14 day(s) ago
AbstractBackgroundNondilated left ventricular cardiomyopathy (NDLVC) has been recently differentiated from dilated cardiomyopathy (DCM). A comprehensive characterization of these 2 entities using c…
Source: www.jacc.orgCategories: General Medicine News, Cardiologists1Tweet
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