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Mashup Score: 2Blood test predicts knee osteoarthritis up to 8 years in advance - 13 hour(s) ago
A blood test successfully predicted most knee osteoarthritis cases up to 8 years before signs of the disease first appeared on X-ray, according to data published in Science Advances. “This confirms our expectation that very early OA is silent and ‘hiding in plain sight’ due to the fact that cartilage tissue has no nerves and therefore can be degraded early on without giving off
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Mashup Score: 1
Use of biologics to treat moderate to severe systemic lupus erythematosus increased 45% between 2021 and 2023, according to recent findings from a market analysis conducted by Spherix Global Insights.The analysis additionally found that nearly half of moderate-to-severe patients with SLE are currently on a biologic. Meanwhile, among those not currently on a biologic, 73% are considered a
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Mashup Score: 0
A biosimilar for golimumab has demonstrated therapeutic equivalence in rheumatoid arthritis, with no clinically meaningful safety differences, according to a press release from the manufacturer. The topline results, announced by Alvotech, stem from a confirmatory clinical study for AVT05, the company’s proposed biosimilar to the TNF alpha inhibitors Simponi and Simponi Aria (golimumab,
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Mashup Score: 0
This year’s Congress of Clinical Rheumatology-East will celebrate the annual meeting’s 40th anniversary with banquets, record in-person attendance and a host of new presenters. “Forty years is a big milestone for us,” David A. McLain, MD, executive director of the Alabama Society for the Rheumatic Diseases, and symposium director of the Congress of Clinical Rheumatology,
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Mashup Score: 3
Patients in rheumatoid arthritis remission who tapered off conventional synthetic disease-modifying antirheumatic drugs had higher risks for flares, with two methods failing to reach non-inferiority vs. stable dosage, according to data. “An increasing number of patients with rheumatoid arthritis achieve sustained remission, even when using first-line treatment with methotrexate and other
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Mashup Score: 0
Aerobic and resistance training are recommended for patients with systemic lupus erythematosus, but should be tailored to the individual and, ideally, supervised by a professional, according to recommendations published in RMD Open. “Despite the clear potential benefits, incorporating physical activity and exercise into the lives of persons living with SLE presents unique challenges,”
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Mashup Score: 6
Approximately 23% of patients with chronic kidney disease meet the criteria for gout, of whom 13% have uncontrolled gout and 36% have no formal gout diagnosis, according to data published in Gout, Urate, and Crystal Deposition Disease. The study additionally found that patients with chronic kidney disease and gout demonstrate significantly more cardiovascular comorbidities and bone diseases.
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Mashup Score: 0
Higher scores on a measure of sinonasal symptoms can predict ANCA-associated vasculitis relapse “months to years” ahead of time, according data published in Arthritis Care & Research. The 22-item Sinonasal Outcome Test (SNOT-22) could enhance prediction of relapse among high-risk patients and may be useful in selectively escalating or de-escalating immunosuppressive therapy, Ellen
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Mashup Score: 1
In this video exclusive, Leonard Calabrese, DO, chief medical editor of Healio Rheumatology, lays out the top stories out of the April issue, including the cover story centering on providers’ priorities regarding work-life balance. “This is really a riff on burnout,” Calabrese said. “It’s about intergenerational differences between practitioners and how we effect
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Mashup Score: 2
I recently had the pleasure of attending a symposium at the Cleveland Clinic that featured an outstanding review of immune-related adverse events, and I was reminded of how far we have come in the decade since I first became involved in the evolution of this disease class.For rheumatologists, this topic — which is covered elsewhere in this issue of Healio Rheumatology by Alexa Meara, MD, a
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🩸A blood test predicted most knee #osteoarthritis cases up to 8 years before signs on X-ray The finding suggests an 'OA continuum' from early to later disease, Dr. Virginia Kraus told us Check Healio for more on this study out of @DukeMedSchool 👇 https://t.co/bhzf3LSBir