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Mashup Score: 27
Background It is unclear how often survival benefits observed in single-center randomized controlled trials (sRCTs) involving critically ill patients are confirmed by subsequent multicenter randomized controlled trials (mRCTs). We aimed to perform a systemic literature review of sRCTs with a statistically significant mortality reduction and to evaluate whether subsequent mRCTs confirmed such reduction. Methods We searched PubMed for sRCTs published in the New England Journal of Medicine, JAMA, or Lancet, from inception until December 31, 2016. We selected studies reporting a statistically significant mortality decrease using any intervention (drug, technique, or strategy) in adult critically ill patients. We then searched for subsequent mRCTs addressing the same research question tested by the sRCT. We compared the concordance of results between sRCTs and mRCTs when any mRCT was available. We registered this systematic review in the PROSPERO International Prospective Register of System
Source: ccforum.biomedcentral.comCategories: General Medicine News, NephrologyTweet
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Mashup Score: 27Positive single-center randomized trials and subsequent multicenter randomized trials in critically ill patients: a systematic review - Critical Care - 15 hour(s) ago
Background It is unclear how often survival benefits observed in single-center randomized controlled trials (sRCTs) involving critically ill patients are confirmed by subsequent multicenter randomized controlled trials (mRCTs). We aimed to perform a systemic literature review of sRCTs with a statistically significant mortality reduction and to evaluate whether subsequent mRCTs confirmed such reduction. Methods We searched PubMed for sRCTs published in the New England Journal of Medicine, JAMA, or Lancet, from inception until December 31, 2016. We selected studies reporting a statistically significant mortality decrease using any intervention (drug, technique, or strategy) in adult critically ill patients. We then searched for subsequent mRCTs addressing the same research question tested by the sRCT. We compared the concordance of results between sRCTs and mRCTs when any mRCT was available. We registered this systematic review in the PROSPERO International Prospective Register of System
Source: ccforum.biomedcentral.comCategories: General Medicine News, NephrologyTweet
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Mashup Score: 5Join our Cloud HD Video Meeting - 1 day(s) ago
Zoom is the leader in modern enterprise video communications, with an easy, reliable cloud platform for video and audio conferencing, chat, and webinars across mobile, desktop, and room systems. Zoom Rooms is the original software-based conference room solution used around the world in board, conference, huddle, and training rooms, as well as executive offices and classrooms. Founded in 2011, Zoom helps businesses and organizations bring their teams together in a frictionless environment to get more done. Zoom is a publicly traded company headquartered in San Jose, CA.
Source: us06web.zoom.usCategories: General Medicine News, NephrologyTweet
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Mashup Score: 1Investigation of Presumptive HIV Transmission... - 2 day(s) ago
This report describes COVID-19 rates, hospitalizations, and vaccination coverage among nursing home residents.
Source: www.cdc.govCategories: General Medicine News, NephrologyTweet
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Mashup Score: 8Warning about hospital staffing shortages - 3 day(s) ago
The Pembroke Hospital says patients should expect longer wait times this summer due to staffing shortages. CTV’s Dylan Dyson reports.
Source: ottawa.ctvnews.caCategories: General Medicine News, NephrologyTweet
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Mashup Score: 235 Food Moves for Lower Blood Pressure via @ConsumerReports - 4 day(s) ago
If you want to improve your blood pressure control through your diet, there’s more you can do than simply lowering your salt intake.
Source: www.consumerreports.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 10Emergency rooms refused to treat pregnant women, leaving one to miscarry in a lobby restroom - 5 day(s) ago
Complaints about pregnant women being turned away from emergency rooms spiked in the months after states began enacting strict abortion laws following the 2022 U.S.
Source: apnews.comCategories: General Medicine News, NephrologyTweet
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Mashup Score: 25
Dr. Javier Neyra graduated from the Universidad Peruana Cayetano Heredia Medical School in Lima, Peru (MD degree), and completed postgraduate training in Int…
Source: www.youtube.comCategories: General Medicine News, NephrologyTweet
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Mashup Score: 1An Introduction to Land Acknowledgment - 6 day(s) ago
An Introduction to Land Acknowledgment video narrated by Can-SOLVE CKD Network patient partner Mary Beaucage. This video is an introduction to the importance…
Source: www.youtube.comCategories: General Medicine News, NephrologyTweet
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Mashup Score: 14'It could be catastrophic': Woman says natural supplement contained hidden painkiller drug - 8 day(s) ago
A Manitoba woman thought she found a miracle natural supplement, but said a hidden ingredient wreaked havoc on her health.
Source: winnipeg.ctvnews.caCategories: General Medicine News, NephrologyTweet
interesting clever paper (h/t @pash22 ) https://t.co/ctRGrw1rR7 single centre RCTs published in JAMA/LANCET/NEJM followed by multicentre RCTs in critically ill population As expected - mostly refuted https://t.co/iJdUlD4Sco