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Mashup Score: 0
This case-control study investigates prescription medication use in patients with sporadic Creutzfeldt-Jakob disease before clinical onset of the disease compared with that of control patients.
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 0Frailty and Implications for Multiple Sclerosis Management - 8 day(s) ago
This Viewpoint discusses the unique needs of patients with multiple sclerosis and frailty and describes the gaps that should be addressed in frailty measurement and clinical management.
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet-
Viewpoint: Assessing frailty in patients with multiple sclerosis enhances neurologists’ ability to understand the variability in health status within this highly heterogeneous disease. https://t.co/Re2Efj3d4w https://t.co/OCifI6vTw4
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Mashup Score: 0Blood-Based Biomarkers for Identifying Disease Activity in AQP4-IgG–Positive Neuromyelitis Optica Spectrum Disorder - 9 day(s) ago
This longitudinal cohort study determines the optimal timing for assessing serum glial fibrillary acidic protein and serum neurofilament light chain and establishes cutoff values differentiating between attack and remission phases in patients with aquaporin-4 antibody (AQP4-IgG)–positive…
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet-
Optimizing serum glial fibrillary acidic protein and serum neurofilament light chain timing and demographic-adjusted cutoffs could improve accuracy in assessing neuromyelitis optica spectrum disorder disease activity. https://t.co/EMvF01myIn @akproebstel https://t.co/on8Cc980Hz
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Mashup Score: 0Epileptiform Electrographic Patterns After Cardiac Arrest - 21 day(s) ago
This Viewpoint challenges conventional clinical practice that eschews pharmacological intervention for comatose patients with epileptiform abnormalities after cardiac arrest using evidence from the Treatment of Electroencephalographic Status Epilepticus after Cardiopulmonary Resuscitation (TELSTAR)…
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet-
Viewpoint challenges conventional clinical practice that eschews pharmacological intervention for comatose patients with epileptiform abnormalities after cardiac arrest using evidence from the TELSTAR trial. https://t.co/npyUMtriGx https://t.co/z5xLeW3VCT
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Mashup Score: 0Intracranial Metastatic Tumor Hemorrhage During MRI Scanning - 22 day(s) ago
This case report describes the presentation and progression of hyperacute active hemorrhage related to an intracranial metastatic tumor as captured by magnetic resonance imaging (MRI).
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet-
Images in Neurology: The presentation and progression of hyperacute active hemorrhage related to an intracranial metastatic tumor as captured by magnetic resonance imaging (MRI). https://t.co/QE07583r23 https://t.co/0adi8ee1Su
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Mashup Score: 0Cognitive Decline After First-Time Transient Ischemic Attack - 26 day(s) ago
This cohort study evaluates if transient ischemic attack is an independent risk associated with cognitive decline when controlling for vascular and demographic factors.
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet-
Most viewed in the last 7 days from @JAMANeuro: Despite the quick resolution of stroke symptoms in transient ischemic attack, there was sufficient impact to be associated with long-term cognitive decline. https://t.co/HSuLuOFzHC https://t.co/exohNvRPms
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Mashup Score: 2Evaluating Treatments for Amyotrophic Lateral Sclerosis - 26 day(s) ago
The HEALEY ALS platform is an innovative first attempt at platform trials in ALS, looking to slow ALS disease progression. Author Sabrina Paganoni, MD, PhD, of Massachusetts General Hospital and Harvard Medical School, discusses results of the first 4 drug regimens from this platform trial and how this study design makes efficient use of resources, with JAMA Deputy Editor Christopher Muth, MD.
Source: edhub.ama-assn.orgCategories: General Medicine News, NeurologyTweet-
@JAMA_current @JAMANetworkOpen From @JAMA_current: The HEALEY ALS platform is an innovative first attempt at platform trials in ALS, looking to slow ALS disease progression. Author Sabrina Paganoni discusses this platform trial with JAMA Deputy Editor Christopher Muth. https://t.co/8nVO8vPILu
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Mashup Score: 2Platform Trials in ALS - 26 day(s) ago
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive weakness of voluntary muscle. ALS is uncommon but not rare, with a lifetime risk of about 1 in 400.1 Nearly all patients with ALS will die from ALS, most from respiratory failure, and the median…
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet-
@JAMA_current @JAMANetworkOpen From @JAMA_current: "The HEALEY ALS platform is a courageous and innovative first attempt at platform trials in ALS." Read the Editorial. https://t.co/BxqlEwWSAf https://t.co/O4EhXOI9dI
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Mashup Score: 1
This Guide to Statistics and Methods provides an overview of platform trials, describes the characteristics that make them more efficient for evidence generation, and discusses their limitations.
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet-
@JAMA_current @JAMANetworkOpen This JAMA Guide to Statistics and Methods provides an overview of platform trials, describes the characteristics that make them more efficient for evidence generation, and discusses their limitations. https://t.co/m1taUNR2Zu https://t.co/h6ztPAsDuv
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Mashup Score: 0Verdiperstat in Amyotrophic Lateral Sclerosis - 26 day(s) ago
This randomized clinical trial investigated the effect of verdiperstat, a myeloperoxidase inhibitor, in amyotrophic lateral sclerosis.
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet-
🧵 Treatment with verdiperstat was unlikely to alter disease progression in amyotrophic lateral sclerosis. https://t.co/9XH9FM5x1d https://t.co/40BEMJ24v2
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Mood alterations may be a common prodromal feature of sporadic Creutzfeldt-Jakob disease. https://t.co/6C76g4MlhY https://t.co/0iNCpeTBaO