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Mashup Score: 11
Background Wastewater surveillance may support early and comprehensive detection of infectious diseases’ community transmission, particularly in settings where other health surveillance systems provide biased or limited information. Amid the SARS-CoV-2 pandemic, deploying passive samplers to monitor targeted populations gained importance. Evaluation of the added public health value of this approach in the field can support its broader adoption. Aim We aimed to assess the feasibility and utility of on-demand wastewater surveillance, employing passive samplers, for SARS-CoV-2 and monkeypox virus (MPXV) in small/targeted populations, also considering ethical aspects. Methods Pilot case studies in the Rotterdam-Rijnmond region were used for a systematic assessment of the feasibility and utility of wastewater monitoring of SARS-CoV-2 (variants) and MPXV using passive sampling. Each case study was instigated by actual questions from the Public Health Service about disease transmission. Resul
Source: www.eurosurveillance.orgCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 30Preliminary analysis of 98 genomic sequences of MPXV clade Ib cases from Burundi, July to September 2024 - 14 hour(s) ago
Preliminary analysis of 98 genomic sequences of MPXV clade Ib cases from Burundi, July to September 2024 Introduction A large mpox clade Ib virus outbreak started in the province of South Kivu in the Democratic Republic of the Congo (DRC) and is rapidly geographically expanding to other areas within the DRC as well as to other countries surrounding the DRC. Especially Burundi is severely affected with close to 1531 confirmed cases of mpox Clade Ib virus infections since the first detection at …
Source: virological.orgCategories: General Medicine News, Infectious DiseaseTweet-
Fabulous work with colleagues in Burundi, who took up Mpox sequencing to understand the situation AND are willing to share pre-publication, shows the expanding tree, and evidence for several introductions not taking off. In progress @EDCTP3 https://t.co/hUdXPk4S5B @1986Bom
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Mashup Score: 151
De vrijdag opgestapte NSC-politica blikt voor het eerst terug op de afgelopen week. Veel vragen blijven nog onbeantwoord.
Source: nos.nlCategories: General Medicine News, Infectious DiseaseTweet-
Wat tijd voor zelfreflectie vanuit het media landschap? https://t.co/0ugQ9qkK9n
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Mashup Score: 15Olaf Koens (@olafkoens.bsky.social) - 3 day(s) ago
Correspondent, schrijver, journalist. ‘When the going gets weird, the weird turn pro.’ https://www.singeluitgeverijen.nl/nijgh-van-ditmar/auteur/olaf-koens/
Source: bsky.appCategories: General Medicine News, Infectious DiseaseTweet-
RT @obk: Nou, vooruit. We beginnen weer eens op 0. 🛼 https://t.co/7d2gyCjzty https://t.co/RjGJRkPqaN
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Mashup Score: 28H5N1 Avian Influenza linked to Mililani Pet Fair - 3 day(s) ago
HONOLULU (KHON2) — A recent investigation by the Hawaii Department of Health (DOH) and the Hawaii Department of Agriculture (HDOA) has confirmed the presence of H5N1 avian influenza in a back…
Source: www.khon2.comCategories: General Medicine News, Infectious DiseaseTweet-
Warning about potential exposure to avian flu in a pet fair in Hawaii . Good to see public health response now that presence of the virus has been confirmed https://t.co/c2OZnlNw6W
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Mashup Score: 17Infectious parvovirus B19 circulates in the blood coated with active host protease inhibitors - 3 day(s) ago
Nature Communications – This study presents the first high-resolution structure of infectious parvovirus B19, purified from a patient. Two acute phase reactants, serpinA3, and ITIH4, bind to the…
Source: www.nature.comCategories: General Medicine News, Infectious DiseaseTweet-
Great study unravelling a mechanism by which parvoviruses can " hide" from host immune responses https://t.co/c3XJTKIUYU
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Mashup Score: 208Den Haag wil de vrijheid aan banden leggen. Niet verrassend dat hun woede zich richt op Halsema - 4 day(s) ago
Met het geweld in Amsterdam heeft rechts de beschavingsoorlog gekregen die het zo vurig wenste. De hoofdstad verwordt tot een principieel rechtstatelijk eiland binnen een land dat in hoog tempo…
Source: www.groene.nlCategories: General Medicine News, Infectious DiseaseTweet-
https://t.co/Tfeb1cDKbL over de veranderende verhoudingen tussen de landelijke politiek en de burgemeester https://t.co/JnAHL49fLv
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Mashup Score: 16Bovine H5N1 influenza virus infection is transmitted by milk causing mortality in suckling neonates - 4 day(s) ago
The spread of H5N1 clade 2.3.4.4b in dairy herds raises concerns about zoonotic transmission due to the high viral load in milk, a key point of contact between livestock and humans. H5N1 clade 2.3.4.4b exhibits tropism for the mammary gland, with milk from infected cows containing high levels of viral RNA and infectious virus. The virus’s ability to infect the mammary gland suggests potential risks of transmission to offspring through breastfeeding. Here, we show that mammary gland infection with bovine H5N1 influenza in lactating ferrets transmits virus and disease to suckling kits. Viral RNA titers significantly increased in milk over time and remained high in mammary gland tissue. Suckling kits had significantly increased viral RNA in the oral and nasal cavity, as well as in feces. However, viral detection in the dam nasal cavities was delayed, with only minimal virus present in the oral cavity. Lung viral RNA levels were low in dams but high in a sampled suckling kit. Additionally,
Source: www.biorxiv.orgCategories: General Medicine News, Infectious DiseaseTweet-
Study of bovine H5N1 influenza strain in ferrets. Intramammary infection leads to transmission of the virus to dams. Would be good to know what is being done to monitor disease in calves https://t.co/WhUAxiCWG0
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Mashup Score: 2
Clinical and epidemiologic evidence from the recent outbreak of Oropouche virus (OROV) has demonstrated increased severity in clinical disease and adverse pregnancy outcomes including miscarriage, stillbirth and neonatal demise. Serological evidence suggests vertical transmission of OROV may be responsible. OROV has not been studied in the context of pregnancy and has unknown ability to infect the relevant tissues of the maternal-fetal interface, which have anti-viral properties; therefore,the mechanisms of vertical transmission are unknown. We used polarized human trophoblast stem cell organoids and human placenta explants to demonstrate that OROV (BeAn19991) infects and replicates in human tissues of the maternal-fetal interface including chorionic villi and the microbial-resistant cell, syncytiotrophoblast. Viral replication is robust within the first 24 hours post infection, and tissues from earlier gestations may be more susceptible to infection. These data indicate tissues at the
Source: www.biorxiv.orgCategories: General Medicine News, Infectious DiseaseTweet-
RT @biorxiv_micrbio: Oropouche virus infects human placenta explants and trophoblast organoids https://t.co/7yQZ3kpT8W #biorxiv_micrbio
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Mashup Score: 177Schoof gaat toch maar naar klimaattop - 6 day(s) ago
Premier Dick Schoof heeft besloten om toch maar naar de klimaattop in Bakoe te gaan.
Source: speld.nlCategories: General Medicine News, Infectious DiseaseTweet-
RT @DeSpeld: Schoof gaat toch maar naar klimaattop https://t.co/bBSoSC5vB7
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On demand wastewater surveillance as an extra tool in the box of methods to understand viral disease outbreaks . Our experiences in the Rotterdam region. https://t.co/TkJtyPYC16