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Mashup Score: 1
Nature – A transient perturbation of transcriptional silencing mediated by Polycomb proteins is sufficient to induce an epigenetic cancer cell fate in Drosophila in the absence of driver mutations.
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Mashup Score: 11Dysregulation of epigenetically induced cancers - 3 day(s) ago
Nature Reviews Genetics – A study in Nature finds that transient perturbation of the Polycomb complex and target epigenome can irreversibly induce cancer cell fates.
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Mashup Score: 0
Nature Biotechnology – Prime editing sensor libraries evaluate diverse genetic variants in their endogenous genomic contexts.
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Mashup Score: 1samgould2 - Overview - 16 day(s) ago
Biology PhD Student at MIT Koch Institute // Sánchez-Rivera Lab – samgould2
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Mashup Score: 8Sociotechnical safeguards for genomic data privacy - 24 day(s) ago
Nature Reviews Genetics – In this Review, the authors describe technical and legal protection mechanisms for mitigating vulnerabilities in genomic data privacy. They also discuss how these…
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Mashup Score: 2Harnessing deep learning for population genetic inference - 24 day(s) ago
Nature Reviews Genetics – Applying deep learning to large-scale genomic data of species or populations is providing new opportunities to understand the evolutionary forces that drive genetic…
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Mashup Score: 236Transposable elements in mammalian chromatin organization - 1 month(s) ago
Nature Reviews Genetics – This Review discusses how transposable elements contribute to mammalian genome evolution and gene regulation through their ability to both maintain and reshape 3D genome…
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Mashup Score: 30Microbiome epidemiology and association studies in human health - 2 month(s) ago
Nature Reviews Genetics – Microbiome epidemiology associates microbial community features with health outcomes, traits or exposures in human host populations. In this Review, the authors discuss…
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Mashup Score: 97
Nature Reviews Genetics – In this Review, the authors discuss our growing knowledge of the underlying genetics of amyotrophic lateral sclerosis (ALS; also known as motor neuron disease). They…
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Mashup Score: 3Principles and methods for transferring polygenic risk scores across global populations - 2 month(s) ago
Nature Reviews Genetics – This Review summarizes the genetic and non-genetic factors that impact the transferability of polygenic risk scores (PRSs) across populations, highlighting the technical…
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Original article: Parreno, V. et al. Transient loss of Polycomb components induces an epigenetic cancer fate. Nature https://t.co/DwfAbihmN9 (2024)