-
Mashup Score: 34
The Scripps Research team fused the enzyme sialidase onto bispecific T-cell engager (BiTE) molecules, helping break down th e cancer cells’ outer barriers and thereby activating T cells against the cancer. Credit: Scripps Research Scripps Research scientists help T cells more effectively kill solid tumors cells in vitro and in mice by tweaking an existing cancer immunotherapy. LA JOLLA, CA — Scientists from Scripps Research have enhanced an existing immunotherapy by removing the sugar coating surrounding
Source: www.scripps.eduCategories: General Medicine News, General HCPsTweet
-
Mashup Score: 24Fixing the misfolded proteins that cause dementia and heart failure: Jeffery Kelly, PhD - Scripps Research - 4 day(s) ago
Fixing the misfolded proteins that cause dementia and heart failure All proteins have a correct way of “folding” themselves into their three-dimensional structures. When this folding process goes awry, including processes leading to protein misassembly, a number of devastating diseases can result. In this free Front Row lecture, Scripps Research professor Jeffery Kelly will share how he is developing novel therapeutic strategies to target these protein misfolding diseases, which lead to deterioration of
Source: frontrow.scripps.eduCategories: General Medicine News, General NewsTweet
-
Mashup Score: 73Three Scripps Research scientists named “Prebys Research Heroes” - Scripps Research Magazine - 5 day(s) ago
Three Scripps Research scientists have been named Prebys Research Heroes: associate chemistry professor Mia Huang, PhD; assistant neuroscience professor Xin Jin, PhD; and neuroscience professor Lisa Stowers, PhD.
Source: magazine.scripps.eduCategories: General Medicine News, General HCPsTweet
-
Mashup Score: 14“Unheard of in Structural Biology” – New Research Unveils Enzymatic Keys to Immune System Regulation - 8 day(s) ago
Scientists at Scripps Research have developed atomic-level structural models of enzymes linked to autoimmune and inflammatory conditions, such as lupus and Alzheimer’s disease. When nucleic acids, such as DNA or RNA, accumulate in a cell’s cytoplasm, they trigger an alert to the immune system. Unde
Source: scitechdaily.comCategories: General Medicine News, General NewsTweet
-
Mashup Score: 7The John C. Martin Memorial Lectureship | 2024 Highlights - 9 day(s) ago
The John C. Martin Memorial Lectureship at Scripps Research was conceived as an annual event where colleagues, friends and family could gather to honor John …
Source: www.youtube.comCategories: General Medicine News, General NewsTweet
-
Mashup Score: 59
LA JOLLA, CA — Inspired by what human liver enzymes can do, Scripps Research chemists have developed a new set of copper-catalyzed organic synthesis reactions for building and modifying pharmaceuticals and other molecules. The new reactions are expected to be widely used in drug discovery and optimization, as well as in other chemistry-based industries. In their study, which initially published in an unedited version on March 28, 2024, in Nature, the chemists showed that their new methods can be used to
Source: www.scripps.eduCategories: General Medicine News, General HCPsTweet
-
Mashup Score: 17Scripps Research on Threads - 13 day(s) ago
April 2024 | 37 min 34 sec Donna Blackmond never thought her career would lead to solving how life first formed on the prebiotic Earth. But as she points out in this episode of Science Changing Life, does any scientist start out knowing where their research will take them? Blackmond, who is a professor and the John C. Martin Endowed Chair in Chemistry at Scripps Research, shares how her wide-ranging background across chemistry and chemical engineering is helping answer some of today’s biggest questions
Source: www.scripps.eduCategories: General Medicine News, General HCPsTweet
-
Mashup Score: 27Scripps Research spin-off’s success highlights institute’s role across biotech and pharma - Scripps Research Magazine - 16 day(s) ago
Science and biotech thought leaders gathered in March for the first event in the Biotech CEO Salon series, featuring an engaging discussion about Scripps Research spin-off Vividion Therapeutics.
Source: magazine.scripps.eduCategories: General Medicine News, General HCPsTweet
-
Mashup Score: 37Scripps Research on Threads - 17 day(s) ago
April 2024 | 37 min 34 sec Donna Blackmond never thought her career would lead to solving how life first formed on the prebiotic Earth. But as she points out in this episode of Science Changing Life, does any scientist start out knowing where their research will take them? Blackmond, who is a professor and the John C. Martin Endowed Chair in Chemistry at Scripps Research, shares how her wide-ranging background across chemistry and chemical engineering is helping answer some of today’s biggest questions
Source: www.scripps.eduCategories: General Medicine News, General HCPsTweet
-
Mashup Score: 29Michael Bollong receives David W. Robertson Award from the American Chemical Society - Scripps Research Magazine - 18 day(s) ago
Michael Bollong, PhD, associate professor of chemistry and the Early Career Endowed Roon Chair for Cardiovascular Research at Scripps Research, has received the David W. Robertson Award for Excellence in Medicinal Chemistry.
Source: magazine.scripps.eduCategories: General Medicine News, General NewsTweet
A new study in @natBME introduces a fusion molecule that merges sialidase with BiTE technology. Led by @pengwuTSRI and Zhuo Yang, PhD, this approach enhanced T-cell effectiveness against #melanoma, breast, and prostate #cancers. More below: https://t.co/LL6hsBOr8d https://t.co/v3gI1Uuhqv