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Mashup Score: 28Hostile Attribution Bias Shapes Neural Synchrony in the Left Ventromedial Prefrontal Cortex during Ambiguous Social Narratives - 13 hour(s) ago
Join this interactive session as Yizhou Lyu, Zishan Su, and Yuan Chang Leong discuss their paper, “Hostile Attribution Bias Shapes Neural Synchrony in the Left Ventromedial Prefrontal Cortex during Ambiguous Social Narratives”, with JNeurosci Reviewing Editor Daniela Schiller. Attendees can submit questions at registration and live during the webinar.
Source: neuronline.sfn.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 4
This image has been selected to showcase the art that neuroscience research can create. As described by Dr M é ndez and colleagues: This confocal microscopy image shows a coronal section of the hippocampus of a mouse. The nuclei of all brain cells are shown in magenta using DAPI, a fluorescent dye that binds the nuclear DNA. In green is a population of inhibitory neurons that express the marker somatostatin (SST). The SST inhibitory neurons express a Green Fluorescent Protein coupled to the optogenetic
Source: blog.eneuro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 3Electrophysiological Properties of Proprioception-Related Neurons in the Intermediate Thoracolumbar Spinal Cord - 2 day(s) ago
Proprioception, the sense of limb and body position, is required to produce accurate and precise movements. Proprioceptive sensory neurons transmit muscle length and tension information to the spinal cord. The function of excitatory neurons in the intermediate spinal cord, which receive this proprioceptive information, remains poorly understood. Using genetic labeling strategies and patch-clamp techniques in acute spinal cord preparations in mice, we set out to uncover how two sets of spinal neurons, Clarke’s column (CC) and Atoh1 -lineage neurons, respond to electrical activity and how their inputs are organized. Both sets of neurons are located in close proximity in laminae V–VII of the thoracolumbar spinal cord and have been described to receive proprioceptive signals. We find that a majority of CC neurons have a tonic-firing type and express a distinctive hyperpolarization-activated current (Ih). Atoh1 -lineage neurons, which cluster into two spatially distinct populations, are mos
Source: www.eneuro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 1Electrophysiological Properties of the Medial Mammillary Bodies across the Sleep–Wake Cycle - 2 day(s) ago
The medial mammillary bodies (MBs) play an important role in the formation of spatial memories; their dense inputs from hippocampal and brainstem regions makes them well placed to integrate movement-related and spatial information, which is then extended to the anterior thalamic nuclei and beyond to the cortex. While the anatomical connectivity of the medial MBs has been well studied, much less is known about their physiological properties, particularly in freely moving animals. We therefore carried out a comprehensive characterization of medial MB electrophysiology across arousal states by concurrently recording from the medial MB and the CA1 field of the hippocampus in male rats. In agreement with previous studies, we found medial MB neurons to have firing rates modulated by running speed and angular head velocity, as well as theta-entrained firing. We extended the characterization of MB neuron electrophysiology in three key ways: (1) we identified a subset of neurons (25%) that exhi
Source: www.eneuro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 0
Phase entrainment of cells by theta oscillations is thought to globally coordinate the activity of cell assemblies across different structures, such as the hippocampus and neocortex. This coordination is likely required for optimal processing of sensory input during recognition and decision-making processes. In quadruple-area ensemble recordings from male rats engaged in a multisensory discrimination task, we investigated phase entrainment of cells by theta oscillations in areas along the corticohippocampal hierarchy: somatosensory barrel cortex (S1BF), secondary visual cortex (V2L), perirhinal cortex (PER), and dorsal hippocampus (dHC). Rats discriminated between two 3D objects presented in tactile-only, visual-only, or both tactile and visual modalities. During task engagement, S1BF, V2L, PER, and dHC LFP signals showed coherent theta-band activity. We found phase entrainment of single-cell spiking activity to locally recorded as well as hippocampal theta activity in S1BF, V2L, PER,
Source: www.eneuro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 10Telling the Stories of Neuroscientific Discovery to Schoolchildren and the Public Can Make an Impact - 4 day(s) ago
Neuroscience research demands focused attention built upon a foundational knowledge that can encompass the full sweep of science and engineering including, among other disciplines, psychology, biology, chemistry, physics, and computer science. Neuroscience studies range from evolution of life-forms to new innovations in computational modeling. Neuroscientists can look at the population-level behavior, activity of the human brain, or atomic-level resolution of essential molecules. And yet, within these depths of emerging knowledge, the neuroscience community has the capacity to share what we know with young people and the public at large. Even little actions of communicating science in a manner that is broadly accessible and fun can initiate that ripple effect that informs a young mind. Television and social media are dominated with advertisements for online shopping, insurance companies, and cell phone plans (Statista, 2022). Furthermore, a number of mental health advertising campaigns
Source: www.eneuro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 1Auditory and Visual Gratings Elicit Distinct Gamma Responses - 4 day(s) ago
Sensory stimulation is often accompanied by fluctuations at high frequencies (>30 Hz) in brain signals. These could be “narrowband” oscillations in the gamma band (30–70 Hz) or nonoscillatory “broadband” high-gamma (70–150 Hz) activity. Narrowband gamma oscillations, which are induced by presenting some visual stimuli such as gratings and have been shown to weaken with healthy aging and the onset of Alzheimer’s disease, hold promise as potential biomarkers. However, since delivering visual stimuli is cumbersome as it requires head stabilization for eye tracking, an equivalent auditory paradigm could be useful. Although simple auditory stimuli have been shown to produce high-gamma activity, whether specific auditory stimuli can also produce narrowband gamma oscillations is unknown. We tested whether auditory ripple stimuli, which are considered an analog to visual gratings, could elicit narrowband oscillations in auditory areas. We recorded 64-channel electroencephalogram from male and
Source: www.eneuro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 2SfN Journals (@sfnjournals) on Threads - 5 day(s) ago
@societyforneuroscience journals JNeurosci and eNeuro serve the field by publishing conceptual advances in neuroscience. 2 Followers.
Source: www.threads.netCategories: General Medicine News, NeurologyTweet
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Mashup Score: 0This Week in The Journal - 5 day(s) ago
Graham H. Davis, Aprem Zaya, and Margaret M. Panning Pearce (see article e1256232024) Diseases characterized by neuron death, such as Huntington’s disease (HD), are strongly associated with the buildup of misfolded proteins into amyloids. How amyloid aggregation leads to the loss of neurons remains unclear, but there is strong support for altered phagocytic glial cell activity promoting inflammation and the buildup and spread of amyloids. This has led to further investigation into how glial cells are altered in neurodegenerative disease states, with the end goal of understanding whether they …
Source: www.jneurosci.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 2Beyond the Paper: A Conversation with Dr. Mahima Sharma - 5 day(s) ago
Interviewed by Dr. Paige N. McKeon, September 28, 2023 In a recent eNeuro publication, Sharma and colleagues investigated an approved treatment for neurorehabilitation called spinal cord stimulation (SCS). While this is an established treatment, its mechanisms of action are still not fully understood. They discovered and characterized an electrophysiological signal evoked by SCS electrodes that represents spinal synaptic currents. They suggest it may serve as a novel biomarker for optimizing SCS. “The
Source: blog.eneuro.orgCategories: General Medicine News, NeurologyTweet-
#eNeuro blog Beyond the Paper | Mahima Sharma, currently advancing her research career at @BuckInstitute, emphasizes how interdisciplinary collaboration is critical for extending benchwork science translatability as we discuss her first author publication. https://t.co/NmK7vFNPYr https://t.co/kUDtRvLSQ0
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Join the discussion with @LouisaLyu1, @Zishan__Su , @YuanChangLeong, and #JNeurosci Reviewing Editor Daniela Schiller on May 28 at 12PM EDT Register now for the #ResearchInConversation webinar: https://t.co/EQXr0cdCUD Catch up on the webinar topic ⬇️ https://t.co/4R1A8WipBM