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Mashup Score: 2MEK Inhibition for RASopathy-Associated Hypertrophic Cardiomyopathy: Clinical Application of a Basic Concept - 2 day(s) ago
The term “RASopathies” designates a group of developmental syndromes that are caused by activating variants of the rat sarcoma virus protein (RAS)/mitogen-activated protein kinase (MAPK) cascade. The most prevalent clinical diagnosis is Noonan syndrome, and other, less prevalent conditions include Noonan syndrome with multiple lentigines, Costello syndrome, cardiofaciocutaneous syndrome, and others. Hypertrophic cardiomyopathy occurs in 10% of these patients and can be severe and life-threating.
Source: onlinecjc.caCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 2Six-Month Progression of Massive Left Ventricular Pseudoaneurysm - 10 day(s) ago
A 59-year-old male patient was referred to our centre after a scheduled outpatient echocardiogram demonstrated that he had a left ventricular (LV) pseudoaneurysm. The patient reported chest pain and dyspnea on exertion. He had a history of delayed presentation myocardial infarction (MI) 6 months prior, with negative cardiac troponin at presentation. At the time of MI, he was a smoker but had no other past medical history of note. Percutaneous intervention, with placement of a drug-eluting stent to a severe mid left anterior descending artery lesion was performed, and thrombotic occlusion of the principal diagonal artery was medically managed.
Source: www.cjcopen.caCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 3
Survival to hospital discharge among patients with out-of-hospital cardiac arrest (OHCA) is low and important regional differences in treatment practices and survival have been described. Since the 2017 publication of the Canadian Cardiovascular Society’s position statement on OHCA care, multiple randomized controlled trials have helped to better define optimal post cardiac arrest care. This working group provides updated guidance on the timing of cardiac catheterization in patients with ST-elevation and without ST-segment elevation, on a revised temperature control strategy targeting normothermia instead of hypothermia, blood pressure, oxygenation, and ventilation parameters, and on the treatment of rhythmic and periodic electroencephalography patterns in patients with a resuscitated OHCA.
Source: onlinecjc.caCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 1The Relationship Between Residential Mobility and Mortality Following Acute Myocardial Infarction - 3 month(s) ago
The extent to which residential mobility is associated with declining health among disease-specific populations, such as survivors of acute myocardial infarction (AMI), remains unknown.
Source: onlinecjc.caCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 3Home Page: Canadian Journal of Cardiology - 4 month(s) ago
Published online: September 14, 2023 Published online: June 30, 2023 Published online: August 8, 2023 Published online: July 26, 2023 The Canadian Journal of Cardiology (CJC) is an official journal of the Canadian Cardiovascular Society (CCS) and a companion title to CJCO and CJCPC. The CJC is a vehicle for the international dissemination of new knowledge in cardiology and cardiovascular science, particularly serving as the major venue for Canadian cardiovascular medicine. The CJC publishes original
Source: onlinecjc.caCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 5
Stroke volume (SV) estimation using transthoracic echocardiography (TTE) is essential for noninvasive hemodynamic assessment and valve disease severity grading.1 The most used TTE method for SV estimation requires the measurement of left ventricular outflow tract (LVOT) cross-sectional area (CSA) and flow velocity data. The LVOT CSA is traditionally calculated according to the LVOT diameter (LVOTd) from the TTE parasternal long-axis view, assuming a circular LVOT shape1 (LVOT CSA = π × [LVOTd/2]2).
Source: onlinecjc.caCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 3Current Issue Table of Contents: Canadian Journal of Cardiology - 6 month(s) ago
Society and NewsAnnouncementsPresident’s PageFocused Clinical Practice UpdateEducation and TrainingTraining/Practice: Training in Cardiovascular Medicine and ResearchJournal News and Commentary: Trainee MattersResearch LettersEditorialClinical ResearchEditorialCase ReportCase ReportClinical ResearchEditorialEditorialClinical ResearchEditorialReviewTraining/Practice: Contemporary Issues in…
Source: onlinecjc.caCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 1Current Issue Table of Contents: Canadian Journal of Cardiology - 7 month(s) ago
Society and NewsAnnouncementsPresident’s PageFocused Clinical Practice UpdateEducation and TrainingTraining/Practice: Training in Cardiovascular Medicine and ResearchJournal News and Commentary: Trainee MattersResearch LettersEditorialClinical ResearchEditorialCase ReportCase ReportClinical ResearchEditorialEditorialClinical ResearchEditorialReviewTraining/Practice: Contemporary Issues in…
Source: onlinecjc.caCategories: Cardiologists1, Latest HeadlinesTweet
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Mashup Score: 11Exercise for Cardiac Rehabilitation in a Warming Climate - 8 month(s) ago
Author links open overlay panel Daniel Gagnon PhD a b c, Audrey-Ann Bartlett BSc a b, Thomas A. Deshayes PhD a b, Laís Manata Vanzella PT, PhD d, Susan Marzolini RKin, PhD d, Paul Oh MD
Source: www.sciencedirect.comCategories: Cardiologists1, Latest HeadlinesTweet
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Mashup Score: 2Pericardial Disease in the Developing World - 9 month(s) ago
Pericardial disease in the developing world is dominated primarily by effusive and constrictive syndromes and contributes to the acute and chronic heart failure burden in many regions. The confluence of geography (location in the tropics), a significant burden of diseases of poverty and neglect, and a significant contribution of communicable diseases to the general burden of disease is reflected in the wide etiological spectrum of causes of pericardial disease. The prevalence of Mycobacterium tuberculosis in particular, is high throughout much of the developing world where it is the most frequent and important cause of pericarditis and is associated with significant morbidity and mortality.
Source: www.onlinecjc.caCategories: Cardiologists1, Latest HeadlinesTweet
RT @CJCJournals: 🤔 What is a #RASopathy? How is it related to #HypertrophicCardiomyopathy? Learn more here! 👉 https://t.co/HVd2CZYIkc #HCM…