• Mashup Score: 33
    Wolters Kluwer Health - 12 month(s) ago

    JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable JavaScript Firefox From the Tools…

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  • Mashup Score: 1

    Nelson et al. explore the abscopal effect, in which irradiation induces responses in adjacent non-irradiated sites, and discuss clinical and preclinical evidence in support of this phenomenon. With growing interest in combining radiotherapy with immunotherapy to elicit systemic anti-tumor responses, additional mechanistic and clinical validation will maximize its effectiveness.

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    • RT @VivekSubbiah: The abscopal effect in patients with cancer receiving immunotherapy @MedCellPress @CellPressNews https://t.co/VMQp7K0KD0

  • Mashup Score: 29

    Genes encoding DNA damage response factors are frequently mutated in cancer, causing genomic instability and presenting opportunities for therapeutic intervention. This Review discusses state-of-the-art strategies for DNA damage response inactivation using small-molecule inhibitors.

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    • RT @NatureRevCancer: NEW content online! Targeting DNA damage response pathways in cancer https://t.co/aK3QAeR6FL https://t.co/9ZfAI2Qyd6

  • Mashup Score: 0

    Kacie Peters and Erik Stanley are extraordinary. Facing dual, concurrent stage IV colorectal cancer diagnoses, they have risen to the challenges posed by thi…

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    • A very special couple and why we continue to fight. #Stage4colonca @CCAlliance @uchealth @CUCancerCenter Married Couple Battling Concurrent Stage IV Colorectal Cancer Diagnoses https://t.co/0wIkxu6qBu via @YouTube

  • Mashup Score: 44

    Metastatic cancer remains almost inevitably a lethal disease. A better understanding of disease progression and response to therapies therefore remains of utmost importance. Here, we characterize the genomic differences between early-stage untreated primary tumors and late-stage treated metastatic tumors using a harmonized pan-cancer (re-)analysis of 7,152 whole-genome-sequenced tumors. In…

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    • RT @Aiims1742: Pan-cancer whole genome comparison of primary and metastatic solid tumors https://t.co/pp3C7ZmYye “5 cancer types - breast,…