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Mashup Score: 910+1 Clinical Tips for Vertical Jump Testing after ACLR - BJSM blog - social media's leading SEM voice - 2 hour(s) ago
Keywords: vertical jumps, testing, ACL, return to sport Vertical jumps play a crucial role in the return-to-sport testing protocol following anterior cruciate ligament reconstruction (ACLR). This recommendation extends beyond athletes in jumping sports, as vertical jumps metrics are sensitive to detect lower limb deficits even without advanced equipment. However, the effectiveness of these tests relies […]Read More…
Source: blogs.bmj.comCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 16Rammya Mathew: We can’t overlook the backdrop as Britain becomes “a sicker nation” - 2 hour(s) ago
Plans by the prime minister, Rishi Sunak, to overhaul the sick note system in the UK have left me with mixed emotions. A more independent process, overseen by professionals skilled in occupational health, will hopefully lead to a more robust system, in which people are supported to get back into work as quickly as possible, when they feel able to. But I worry that removing GPs from the decision making will create a less compassionate process that’s unduly stressful for patients, most of whom are genuinely struggling to cope. Some …
Source: www.bmj.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 1Need for truthfulness in dementia research - 2 hour(s) ago
Walsh and colleagues call for prudence in their editorial on lecanemab for Alzheimer’s disease. This call should be extended to dementia and Alzheimer’s disease research as a whole.1 The “hyperbolic rhetoric” the authors identify is not exclusive to lecanemab—in our discipline, treatments are so desperately needed that evidence for many therapies is …
Source: www.bmj.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 0PHAROS – severe Pulmonary Hypertension mAnagement acROSs Europe - ERS - European Respiratory Society - 2 hour(s) ago
ERS is an international membership organisation that unites physicians, health professionals, scientists and other experts working in respiratory medicine.
Source: www.ersnet.orgCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 4Spending cuts are often false economies that end up costing society dearly | Torsten Bell - 2 hour(s) ago
New research has found that every pound saved in closing police stations costs the rest of us ÂŁ3
Source: www.theguardian.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 0
Objective To determine whether the combined use of glucagon-like peptide-1 (GLP-1) receptor agonists and sodium-glucose cotransporter-2 (SGLT-2) inhibitors is associated with a decreased risk of major adverse cardiovascular events and serious renal events compared with either drug class alone among patients with type 2 diabetes, and to assess the effect of the combination on the individual components of major adverse cardiovascular events, heart failure, and all cause mortality. Design Population based cohort study using a prevalent new-user design, emulating a trial. Setting UK Clinical Practice Research Datalink linked to Hospital Episode Statistics Admitted Patient Care and Office for National Statistics databases. Participants Two prevalent new-user cohorts were assembled between January 2013 and December 2020, with follow-up until the end of March 2021. The first cohort included 6696 patients who started GLP-1 receptor agonists and added on SGLT-2 inhibitors, and the second includ
Source: www.bmj.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 1Observing one-divalent-metal-ion dependent and histidine-promoted His-Me family I-PpoI nuclease catalysis in crystallo - 2 hour(s) ago
Metal-ion-dependent nucleases play crucial roles in cellular defense and biotechnological applications. Time-resolved crystallography has resolved catalytic details of metal-ion-dependent DNA hydrolysis and synthesis, uncovering the essential roles of multiple metal ions during catalysis. The superfamily of His-Me nucleases is renowned for binding one divalent metal ion and requiring a conserved histidine to promote catalysis. Many His-Me family nucleases, including homing endonucleases and Cas9 nuclease, have been adapted for biotechnological and biomedical applications. However, it remains unclear how this single metal ion in His-Me nucleases, together with the histidine, promotes water deprotonation, nucleophilic attack, and phosphodiester bond breakage. By observing DNA hydrolysis in crystallo with His-Me I-PpoI nuclease as a model system, we proved that only one divalent metal ion is required during its catalysis. Moreover, we uncovered several possible deprotonation pathways for
Source: www.biorxiv.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 2How the NHS has run out of jobs for new doctors - 2 hour(s) ago
The NHS needs more doctors so why have some medical students been left in limbo waiting for a job?
Source: www.bbc.co.ukCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 8
The number of drugs in short supply — including those for life-threatening conditions — has risen dramatically, leaving pharmacies unable to help patients
Source: www.thetimes.co.ukCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 0Faces of Glaucoma - 2 hour(s) ago
Andrew Stewart of Bausch + Lomb discusses the company’s latest campaign, Faces of Glaucoma
Source: theophthalmologist.comCategories: General Medicine News, OphthalmologyTweet
🚨 10+1 #ClinicalTips for vertical jump testing after ACLR It's about more than just conducting the test: ✅ Selecting the right tests ✅ Adhering to relevant metrics ✅ Understanding the purpose behind the testing NEW #BJSMBlog ➡️ https://t.co/oy6zEbjMI4 https://t.co/qoO93xrPP1