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Mashup Score: 8
The COVID-19 pandemic has disproportionately impacted immunocompromised patients. This diverse group is at increased risk for impaired vaccine responses, progression to severe disease, prolonged hospitalizations and deaths. At particular risk are people with deficiencies in lymphocyte number or function such as transplant recipients and those with hematologic malignancies. Such patients’ immune…
Source: EClinicalMedicineCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 1High-dose ubiquinol supplementation in multiple-system atrophy: a multicentre, randomised, double-blinded, placebo-controlled phase 2 trial - 1 year(s) ago
High-dose ubiquinol was well-tolerated and led to a significantly smaller decline of UMSARS part 2 score compared with placebo.
Source: EClinicalMedicineCategories: Latest Headlines, PayerTweet-
New multicentre phase 2 RCT: High-dose ubiquinol supplementation in multiple-system atrophy #MSA Findings suggested that high-dose ubiquinol was well-tolerated and led to a significantly smaller decline of UMSARS part 2 score compared with placebo https://t.co/eCj1a1zBkn https://t.co/cvwkRpZguf https://t.co/qlnr3OCHaR
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Mashup Score: 0
The harms of exercise in patients with cancer undergoing systemic treatment are uncertain, and there is currently insufficient data on harms to make evidence-based risk-benefits assessments of the application of structured exercise in this population.
Source: EClinicalMedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 8
This work describes, for the first time to our knowledge, functional differences within olfactory areas and regions involved in sensory processing and cognitive functioning. This work identifies key areas for further research and potential target sites for therapeutic strategies.
Source: EClinicalMedicineCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 1Assessment of vaccine herd protection in a cluster-randomised trial of Vi conjugate vaccine against typhoid fever: results of further analysis - 1 year(s) ago
Our analysis did not reveal Vi-TT herd protection in the trial. Consideration should be given to exploring whether targeting adults as well as children with Vi-TT yields appreciable levels of vaccine herd protection.
Source: EClinicalMedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Further analysis of vaccine herd protection in a cluster-randomised trial of Vi conjugate vaccine against #typhoid fever The absence of herd protection when the vaccine was targeted only to children suggest this targeting strategy might not be sufficient https://t.co/S2xrllUsah https://t.co/sEkelR9ynG
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Mashup Score: 1High-dose ubiquinol supplementation in multiple-system atrophy: a multicentre, randomised, double-blinded, placebo-controlled phase 2 trial - 1 year(s) ago
High-dose ubiquinol was well-tolerated and led to a significantly smaller decline of UMSARS part 2 score compared with placebo.
Source: EClinicalMedicineCategories: Expert Picks, Latest HeadlinesTweet
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Mashup Score: 1Pregnancy and neonatal outcomes among women with early-onset colorectal cancer: a nationwide case–control study - 1 year(s) ago
In this population-based study, maternal history of early-onset colorectal cancer was associated with risk of both adverse pregnancy (pre-eclampsia, C-section) and neonatal outcomes (preterm birth).
Source: EClinicalMedicineCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1Does this person have obesity? - 1 year(s) ago
According to the World Obesity Federation, obesity is a chronic, relapsing, progressive disease.1 This view of obesity, however, is not without controversy. Opinions range from “fat acceptance activists”, who argue that the health impact of excess body fat are exaggerated and a cover for cultural and aesthetic prejudices against people who live in large bodies, to the Health At Every Size (HAES®)…
Source: EClinicalMedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 2Magnetic resonance imaging reference values for cardiac morphology, function and tissue composition in adolescents - 1 year(s) ago
This cross-sectional study provides overall and sex-stratified CMR reference values for cardiac dimensions and function, and myocardial tissue properties, in adolescents. This information is useful for clinical practice and may help in the differential diagnosis of cardiac diseases, such as cardiomyopathies and myocarditis, in this population.
Source: EClinicalMedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Magnetic resonance imaging reference values for cardiac morphology, function and tissue composition in adolescents This study provides overall and sex-stratified CMR reference values for cardiac dimensions and function, and myocardial tissue properties https://t.co/Sxc3MqBEmb https://t.co/b1zNbL6lMg
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Mashup Score: 0
Phenotype-tailored lifestyle interventions may result in significant weight loss, but a randomised controlled trial is required to confirm causality.
Source: EClinicalMedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
Latest from our @TheLancet Commission on COVID-19: In @eClinicalMed Vaccines and Therapeutics for Immunocompromised Patients paper led by @ShohamTxID @johnshopkins also @mebottazzi and our vaccine and therapeutics task force https://t.co/FOHrgAV0L6