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Mashup Score: 27European Respiratory Society Clinical Practice Guideline on symptom management for adults with serious respiratory illness - 4 day(s) ago
Respiratory symptoms are ubiquitous and impair health-related quality of life in people with respiratory disease. This European Respiratory Society (ERS) task force aimed to provide recommendations for symptomatic treatment in people with serious respiratory illness. The ERS task force comprised 16 members, including representatives of people with serious respiratory illness and informal caregivers. Seven questions were formulated, six in the “Population, Intervention, Comparison, Outcome” (PICO) format, which were addressed with full systematic reviews and evidence assessed using Grading of Recommendations Assessment, Development and Evaluation (GRADE). One question was addressed narratively. An “evidence-to-decision” framework was used to formulate recommendations. To treat symptoms in people with serious respiratory illness, the task force suggests the use of graded exercise therapy (conditional recommendation, low certainty of evidence); and suggests the use of a multicomponent ser
Source: erj.ersjournals.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 23The longitudinal microbial and metabolic landscape of infant cystic fibrosis: the gut–lung axis - 8 day(s) ago
Insights into CF infants’ gut–lung microbiome and metabolome reveal potential biomarkers and targets for disease management and tailored treatment. Stool should be explored for noninvasive screening of Pseudomonas in non-expectorating patients. https://bit.ly/3wFVrnr
Source: erj.ersjournals.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 0
Uptake of stop smoking support co-located within a lung cancer screening programme was high across a range of participant demographics and quit rates were in excess of those reported in other studies at similar time-points without such intervention. https://bit.ly/3vc8bln
Source: erj.ersjournals.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 22
B-cells are recruited to and activated in PAH lungs and contribute to vascular remodelling through production of autoantibodies targeting the lung vasculature and cytokines. B-cell targeted therapies are a promising direction for select PAH conditions. https://bit.ly/3T9mNde
Source: erj.ersjournals.comCategories: General Medicine News, PulmonologyTweet-
B-cells are recruited to and activated in PAH lungs and contribute to vascular remodelling through production of autoantibodies targeting the lung vasculature and cytokines. B-cell targeted therapies are a promising direction for select PAH conditions. https://t.co/AOg6T52pVp https://t.co/K1D9mgW4JE
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Mashup Score: 14
Smoking cessation at lung cancer screening is viable and an excellent opportunity https://bit.ly/3TC0HAf
Source: erj.ersjournals.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 45
Our growing understanding of how the epithelium and epithelial cytokines orchestrate airway remodelling in severe asthma is enabling the development of new therapies that may make disease remission a realistic treatment goal https://bit.ly/3UOblpT
Source: erj.ersjournals.comCategories: General Medicine News, PulmonologyTweet-
European Respiratory Journal: Our growing understanding of how the epithelium and epithelial cytokines orchestrate airway remodelling in severe asthma is enabling the development of new therapies that may make disease remission a realistic treatment goal https://t.co/xkRmush3GM https://t.co/e03YXvueaj
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Mashup Score: 6Precision medicine in cystic fibrosis: predictive role of forskolin-induced swelling assay - 27 day(s) ago
The FIS assay generally indicates responsiveness to CFTR modulators, but it cannot discriminate between high and low responders within the F508del homozygous subjects. Higher FIS response in intestinal organoids did not predict better clinical outcomes. https://bit.ly/3VgaHSj
Source: erj.ersjournals.comCategories: General Medicine News, PulmonologyTweet-
The FIS assay generally indicates responsiveness to CFTR modulators, but it cannot discriminate between high and low responders within the F508del homozygous subjects. Higher FIS response in intestinal organoids did not predict better clinical outcomes. https://t.co/Ye7ZKXhfeB https://t.co/hctWpLbIJC
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Mashup Score: 1Early life exposure to pollens and increased risks of childhood asthma: a prospective cohort study in Ontario children - 29 day(s) ago
Increased exposure to tree canopy around the place of residence at birth prevented the risk of childhood asthma development, but this protective effect can be reduced when exposure to weed and tree pollen increases https://bit.ly/3Tboabo
Source: erj.ersjournals.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 30
Uptake of stop smoking support co-located within a lung cancer screening programme was high across a range of participant demographics and quit rates were in excess of those reported in other studies at similar time-points without such intervention. https://bit.ly/3vc8bln
Source: erj.ersjournals.comCategories: General Medicine News, PulmonologyTweet-
ERJ: Uptake of stop smoking support co-located within a lung cancer screening programme was high across a range of participant demographics and quit rates were in excess of those reported in other studies at similar time-points without such intervention. https://t.co/U0kcaWkYG2 https://t.co/OGvlt9gNy2
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Mashup Score: 98Objective sputum colour assessment and clinical outcomes in bronchiectasis: data from the European Bronchiectasis Registry (EMBARC) - 30 day(s) ago
Sputum colour is a simple non-invasive marker of airway inflammation that identifies patients with bronchiectasis at higher risk of exacerbation, hospitalisation and mortality https://bit.ly/3HczGxO
Source: erj.ersjournals.comCategories: General Medicine News, PulmonologyTweet
The new ERS Clinical Practice Guideline on symptom management for adults with serious respiratory illness is now available via the European Respiratory Journal. Access it online: https://t.co/3gEbXiqQU7 @ERSpublications https://t.co/DqvuCZ0cnp