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Mashup Score: 16
Objective Skew deviation results from a dysfunction of the graviceptive pathways in patients with an acute vestibular syndrome (AVS) leading to vertical diplopia due to vertical ocular misalignment. It is considered as a central sign, however, the prevalence of skew and the accuracy of its test is not well known . Methods We performed a prospective study from February 2015 until September 2020 of…
Source: Journal of NeurologyCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1
Background Identifying the cause of non-traumatic coma in the emergency department is challenging. The clinical neurological examination is the most readily available tool to detect focal neurological deficits as indicators for cerebral causes of coma. Previously proposed clinical pathways have granted the interpretation of clinical findings a pivotal role in the diagnostic work-up. We aimed to…
Source: Journal of NeurologyCategories: Latest Headlines, PediatricsTweet
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Mashup Score: 4Serum neurofilament light chain (sNfL) values in a large cross-sectional population of children with asymptomatic to moderate COVID-19 - 3 year(s) ago
Background Serum neurofilament light chain (sNfL) is an established biomarker of neuro-axonal damage in multiple neurological disorders. Raised sNfL levels have been reported in adults infected with pandemic coronavirus disease 2019 (COVID-19). Levels in children infected with COVID-19 have not as yet been reported. Objective To evaluate whether sNfL is elevated in children contracting COVID-19….
Source: Journal of NeurologyCategories: Latest Headlines, PediatricsTweet-
Neuronal damage in #kids with #COVID19? First data from CoKiBa trial (including 2652 children) show no neurochemical (NfL) signs of #braindamage in kids with asymptomatic to moderate course, in contrast to adults. #developingandapplyingresearch More on: https://t.co/Hk5GYBwBKQ https://t.co/5mxkBAMlMp
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Mashup Score: 0Early life serum neurofilament dynamics predict neurodevelopmental outcome of preterm infants - 3 year(s) ago
Background and purpose To determine whether neurofilament light chain (NfL), a promising serum and cerebrospinal fluid (CSF) biomarker of neuroaxonal damage, predicts functional outcome in preterm infants with neonatal brain injury. Methods Our prospective observational study used a sensitive single-molecule array assay to measure serum and CSF NfL concentrations in preterm infants with moderate…
Source: Journal of NeurologyCategories: Latest Headlines, PediatricsTweet
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Mashup Score: 2
Dear Sirs,New York City (NYC) was the first epicenter of the coronavirus disease 2019 (COVID-19) pandemic in the United States. Beginning in mid-March 2020, the number of deaths in NYC increased above the typical ~ 1000/week,…
Source: Journal of NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 1Association of neuronal injury blood marker neurofilament light chain with mild-to-moderate COVID-19 - 4 year(s) ago
Dear Sir,Even though the coronavirus disease 2019 (COVID-19) affects primarily the respiratory system some reports describe nervous system involvement as well [1,2,3]. Headache and anosmia have been frequently described as…
Source: Journal of NeurologyCategories: Latest Headlines, PediatricsTweet
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Mashup Score: 1Screening for genetic mutations in patients with neuropathy without definite etiology is useful - 4 year(s) ago
To determine the clinical usefulness of systemic genetic testing in neuropathies without definite etiology. We systematically performed genetic testing in all patients with neuropathy who did not have a definite etiology, seen at our neuromuscular clinic between 2017 and 2020. The testing consisted of an inherited neuropathy panel (72–81 genes), which used next-generation sequencing technology….
Source: Journal of NeurologyCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0
Neuronal antibodies can cause encephalopathy syndromes often presenting with subacute cognitive impairment, sometimes resembling neurodegenerative dementias. We searched Medline and Embase for studies reporting associations between neuronal surface antibodies in all-cause dementia versus controls. Random-effects meta-analysis was used to pool adjusted estimates across studies. Six studies were…
Source: Journal of NeurologyCategories: Latest Headlines, NeurologyTweet
Acute vestibular syndrome: is skew deviation a central sign? Journal of Neurology 2021; DOI: https://t.co/H8qmCjlnVU https://t.co/JGxSF8UQoM