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Mashup Score: 0
Frailty, defined as an age-related state of increased vulnerability to acute stressors, is a major challenge in the care of older people with haematological malignancies. Growing evidence from multiple studies suggests that a systematic evaluation of frailty in these patients by use of appropriate assessment tools might help clinicians to make appropriate treatment decisions and initiate frailty…
Source: The Lancet Healthy LongevityCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Implementation of geriatric haematology programmes for the treatment of older people with haematological malignancies in low-resource settings - 1 year(s) ago
In 2020, about 600 000 people aged 65 years and older were diagnosed with a haematological malignancy worldwide, and this number will increase to almost 1 million by 2040, with the largest growth taking place in regions with less developed economies. Health-care systems globally are ill-prepared to face this impending increase in the burden of haematological malignancies among older people, and…
Source: The Lancet Healthy LongevityCategories: Hem/Oncs, Latest HeadlinesTweet-
#Hematology Implementation of geriatric haematology programmes for the treatment of older people with haematological malignancies in low-resource settings #geriheme #lymsm #mmsm #leusm https://t.co/GNLQBDuE1s
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Mashup Score: 1Open Life Data to support healthy longevity for all - 1 year(s) ago
Building on The Health of the Nation report,1 the All-Party Parliamentary Group for Longevity is now engaging with the UK Government on how to improve Britain’s health and reduce the grave inequalities laid bare by COVID-19.2 The Levelling Up Health report, published on April 9, 2021, outlines plans to achieve the Government’s manifesto commitment to add 5 years of healthy life expectancy while…
Source: The Lancet Healthy LongevityCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
RT @MarkDuman: Open Life #Data to Support Healthy Longevity for All, #digitalhealth Arun Sujenthiran MD https://t.co/DmJuEFTySw
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Mashup Score: 1
Results showed that reliable improvement in anxiety from psychological therapy was associated with reduced incidence of future dementia. There are multiple plausible explanations for this finding and further research is needed to distinguish between these possibilities. Missing data in the sample limit reliability of findings.
Source: The Lancet Healthy LongevityCategories: Healthcare Professionals, Latest HeadlinesTweet-
Improvement in #anxiety symptoms following psychological intervention is associated with reduced incidence of all-cause #dementia, Alzheimer's disease, and vascular dementia. https://t.co/K8Lf9mArI2 https://t.co/cJbxc5JKx7
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Mashup Score: 0
Geriatrician assessment was associated with a reduced risk of death for seriously injured older people. These data support routine provision of geriatrician assessment in trauma care. Future research should explore the key components of a geriatrician assessment paired with a health economic evaluation.
Source: The Lancet Healthy LongevityCategories: Hem/Oncs, Latest HeadlinesTweet-
So when I read the FiTR 2 study @LancetLongevity, which suggests that older people with traumatic injuries who are reviewed by a geriatrician have a lower mortality, something seemed a little fishy 🐟https://t.co/GmQaqsYt1T
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Mashup Score: 1
A retrospective observational study in The Lancet Healthy Longevity of more than 35 000 older people admitted to hospital following a serious traumatic injury found an association between geriatrician assessment and improved survival.1 Philip Braude and colleagues reported an adjusted hazard ratio (aHR) for death of 0·43 (95% CI 0·40–0·46; p<0·0001) among patients assessed by a geriatrician...
Source: The Lancet Healthy LongevityCategories: Hem/Oncs, Latest HeadlinesTweet-
So in summary, while we highly value the input & expertise of our geriatrician colleagues, an observational study is perhaps not the best way to establish a causal link between review by any physician & mortality. Read our correspondence @LancetLongevity: https://t.co/16gvv4JIHn
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Mashup Score: 0
Overly stringent RCT exclusion criteria do not appropriately account for the heterogeneity of vulnerable characteristics observed in real-world populations. Treatment decision information is scarce for such individuals, which might affect health outcomes. We discuss the challenges facing the inclusivity of such individuals and highlight the strength of real-world evidence as an integrative…
Source: The Lancet Healthy LongevityCategories: Hem/Oncs, Latest HeadlinesTweet-
Comparing clinical trial population representativeness to real-world populations: an external validity analysis encompassing 43 895 trials and 5 685 738 individuals across 989 unique drugs and 286 conditions in England https://t.co/W8furbRkls via @JustYenYi et al https://t.co/i1ETJtTWZ6
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Mashup Score: 2Life course, genetic, and neuropathological associations with brain age in the 1946 British Birth Cohort: a population-based study - 2 year(s) ago
Brain-PAD was associated with cardiovascular risk, and imaging and biochemical markers of neurodegeneration. These findings support brain-PAD as an integrative summary metric of brain health, reflecting multiple contributions to pathological brain ageing, and which might have prognostic utility.
Source: The Lancet Healthy LongevityCategories: Cardiologists, Latest HeadlinesTweet-
Nice combination of epidemiology and data science to show that worse cardiovascular health at age 36 is associated with a higher brain age later in life. Also, men tended to have higher brain age than women of the same age. https://t.co/XKH4Huj5Ww
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Mashup Score: 7Refining frailty in relapsed or refractory multiple myeloma: adding the patient voice - 2 year(s) ago
Multiple myeloma is an incurable haematological malignancy with a rapidly evolving treatment landscape. Despite novel therapies, ageing-associated vulnerabilities can complicate the treatment of older adults with this condition.1 The International Myeloma Working Group (IMWG) frailty score predicts treatment-related toxicity and mortality for older adults with newly diagnosed multiple myeloma. By…
Source: The Lancet Healthy LongevityCategories: Hem/Oncs, Latest HeadlinesTweet-
Love seeing my mentee @KellySchoenbeck find her niche in #gerionc: her commentary on a recent @LancetLongevity paper on relationship between PROs and frailty in older adults with #myeloma #mmsm https://t.co/p8eCwq40MY https://t.co/FzmjIu7VNo
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Mashup Score: 14Life course, genetic, and neuropathological associations with brain age in the 1946 British Birth Cohort: a population-based study - 2 year(s) ago
Brain-PAD was associated with cardiovascular risk, and imaging and biochemical markers of neurodegeneration. These findings support brain-PAD as an integrative summary metric of brain health, reflecting multiple contributions to pathological brain ageing, and which might have prognostic utility.
Source: The Lancet Healthy LongevityCategories: Latest Headlines, NeurologyTweet-
“Life course, genetic, and neuropathological associations with brain age in the British 1946 birth cohort: a population-based study” by Jonathan Schott et al. Lancet Healthy Longevity https://t.co/nrdafoPjN7
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#Hematology #Frailty assessment in the care of older people with haematological malignancies #geriheme #lymsm #mmsm #leusm https://t.co/rO4R7nd1XQ