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Mashup Score: 10
BackgroundThe comparison of coronary computed tomography angiography plaques and perivascular adipose tissue (PVAT) between patients with acute myocardial infarction (AMI) posttreatment and patient…
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 1Contemporary State-of-the-Art PCI of Left Main Coronary Artery Disease | Circulation: Cardiovascular Interventions - 5 hour(s) ago
The left main coronary artery (LMCA) supplies over 70% of the myocardium, and significant LMCA disease is associated with high morbidity and mortality. With remarkable advances in percutaneous coronary intervention (PCI), including stent technology, antithrombotic agents, and evolving procedural techniques, PCI has become an important treatment option in clinical practice guidelines for the revascularization of LMCA disease. In contemporary clinical practice, a heart-team approach to shared decision-making, considering clinical/anatomic factors along with patient preferences, is emphasized for patients with significant LMCA disease requiring myocardial revascularization. Furthermore, recent progress in PCI procedures combined with intravascular imaging or functional guidance has resulted in significant improvements in PCI outcomes, especially for complex lesions, including LMCA disease. Nevertheless, owing to inherent anatomic complexities and frequent multivessel involvement, several
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet-
Contemporary State-of-the-Art PCI of Left Main Coronary Artery Disease | Circulation: Cardiovascular Interventions https://t.co/MtFs56tj4L
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Mashup Score: 3
BackgroundThe Direct Oral Anticoagulant (DOAC) Score can predict bleeding risk in patients with atrial fibrillation taking DOACs; however, it lacks external validation. Therefore, this study aimed …
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet-
Higher DOAC Score correlates with increased bleeding events after TAVR in AF patients from a Japanese multicenter study. #AHAJournals @ecg_dr https://t.co/M6U4HZ5UGB https://t.co/ejZjJMBIpw
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Mashup Score: 3
BackgroundLung ultrasound (LUS) has emerged as a useful tool in the acute phase of patients admitted for ST‐segment–elevation myocardial infarction. However, its long‐term significance remains unce…
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet-
In STEMI patients, admission LUS predicted adverse outcomes (death, stroke, HF, ACS) over one year and improved GRACE risk score predictions. #AHAJournals @jose_carmora @ASionis @miguelcainzos23 @beavaquerizo @m_rivaslasarte @hospitaldelmar @HMar_research https://t.co/UlTAMRDidu https://t.co/2J6b4c4DnK
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Mashup Score: 29Rescue Stenting for Failed Mechanical Thrombectomy in Acute Basilar Artery Occlusions: Analysis of the PC-SEARCH Registry | Stroke - 7 hour(s) ago
Background: We aimed to investigate whether rescue stenting (RS) following failed mechanical thrombectomy (MT) for acute basilar artery occlusion (BAO) results in superior functional outcomes and enhanced safety compared to the natural history of failed mechanical thrombectomy (MT). Methods: This retrospective cohort study utilized data from the PC-SEARCH registry, encompassing eight high-volume centers in the United States and covering the period from 2015 to 2021. Patients with BAO who experienced failed MT (mTICI score of 0-2a after at least one attempt of clot retrieval) were categorized based on whether they received additional intervention with RS. The primary outcome was a shift analysis of the 90-day mRS. Multivariable logistic regression was employed to assess both efficacy and safety outcomes. Results: Of a total of 444 patients, 119 presented failed MT and were included in the analysis. The RS group comprised 65 (14.6%) patients, while the control group consisted of 54 (12.2
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet-
#STROKE: Rescue stenting in acute basilar artery occlusion is associated with improved functional outcomes and reduced mortality after mechanical thrombectomy failure, an analysis of the PC-SEARCH registry. #SVIN24 #AHAJournals https://t.co/syrmWcV6n7 https://t.co/LfMJlvJaGr
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Mashup Score: 0
Sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) and glucagon‐like peptide‐1 receptor agonists (GLP‐1RA) are key therapies to prevent cardiovascular and kidney events in p atients with type 2 diabetes (T2D). 1 The American College of Cardiology/American Heart Association recommends these medications for primary prevention of cardiovascular disease (CVD) in people with T2D and additional CVD risk factors. 2 Despite these recommendations, SGLT2i/GLP‐1RA use is low. 3 Moreover, whether these drugs are
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet-
Looking back at NHANES data from 2013-2020 suggests that many people with diabetes may have benefited from the use of GLP‐1RAs and SGLT2is. #AHAJournals #ResearchLetter @NYUGSOM_PMED @NYULH_DeptofMed @JHUWelchCenter https://t.co/uj6XgrB8mT https://t.co/bjzjhhL16G
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Mashup Score: 1Association of Lipoprotein(a) With Changes in Coronary Atherosclerosis in Patients Treated With Alirocumab | Circulation: Cardiovascular Imaging - 8 hour(s) ago
BACKGROUND: Elevated Lp(a) (lipoprotein[a]) is a risk marker for atherosclerotic disease, but the underlying mechanisms remain elusive. We examined the association of Lp(a) with changes in coronary atherosclerosis following intensive lipid-lowering therapy. METHODS: In the PACMAN-AMI trial (Effects of the PCSK9 Antibody Alirocumab on Coronary Atherosclerosis in Patients With Acute Myocardial Infarction), 300 patients with acute myocardial infarction were randomized to receive biweekly alirocumab 150 mg or placebo in addition to high-intensity statins. Patients underwent serial 2-vessel intravascular ultrasound, optical coherence tomography, and near-infrared spectroscopy in the non–infarct-related arteries at baseline and after 52 weeks. The main end points were percent atheroma volume by intravascular ultrasound, minimum fibrous cap thickness by optical coherence tomography, and maximum lipid core burden index within 4 mm (maxLCBI4mm) by near-infrared spectroscopy. RESULTS: A total of
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Association of Lipoprotein(a) With Changes in Coronary Atherosclerosis in Patients Treated ... - https://t.co/V016uqZbmH @Lpa_Doc
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Mashup Score: 0Gut Hormones in Heart Failure | Circulation: Heart Failure - 8 hour(s) ago
Heart failure (HF) is a syndrome affecting all organ systems. While some organ interactions have been studied intensively in HF (such as the cardiorenal interaction), the endocrine gut has to some degree been overlooked. However, there is growing evidence of direct cardiac effects of several hormones secreted from the gastrointestinal tract. For instance, GLP-1 (glucagon-like peptide-1), an incretin hormone secreted from the distal intestine following food intake, has notable effects on the heart, impacting heart rate and contractility. GLP-1 may even possess cardioprotective abilities, such as inhibition of myocardial ischemia and cardiac remodeling. While other gut hormones have been less studied, there is evidence suggesting cardiostimulatory properties of several hormones. Moreover, it has been reported that patients with HF have altered bioavailability of numerous gastrointestinal hormones, which may have prognostic implications. This might indicate an important role of gut hormon
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet-
This review sheds light on the link between gut hormones and HF, pointing to new avenues for advancing HF management #AHAJournals https://t.co/zBvkbWjWnO https://t.co/5PLWvX4oVE
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Mashup Score: 7
BACKGROUND: Veterans are disproportionately more likely to experience homelessness and unstable housing (HUH) compared with the general population. Cardiovascular disease is the leading cause of death among Veterans experiencing HUH. We aimed to understand whether HUH status among Veterans with preexisting cardiovascular disease was associated with disparities in cardiovascular care access and utilization. METHODS: Retrospective study of all Veterans with preexisting cardiovascular disease between 2017 and 2019 using Veterans Affairs Corporate Data Warehouse and Homeless registry data. Primary outcomes were annual outpatient visits for cardiovascular disease management and visits with cardiovascular disease–related specialists. Secondary outcomes included cardiovascular disease–related procedures and emergency department visits and hospitalizations. HUH status was determined based on response to a screener, diagnostic codes, or use of homelessness services, and outcomes were assessed i
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet-
Veterans with CV disease experiencing homelessness & housing instability had fewer visits for CV disease management or with specialists but more ED visits and hospitalizations than similar housed Veterans @SameedKhatana @PennLDI @PennCardiology https://t.co/kXRKAOoe3u https://t.co/ioJiGXYvKl
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Mashup Score: 1
BackgroundCurrently, there is a lack of evidence for the long‐term bioprosthetic valve durability of patients with bicuspid aortic valve (BAV) following transcatheter aortic valve replacement (TAVR…
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet-
#TAVR in patients with BAV demonstrates long-term valve durability. Patients with #BAV achieve comparable hemodynamic outcomes, structural valve deterioration, & bioprosthetic valve failure rates as those with #TAV during long-term follow-up. #AHAJournals https://t.co/gvBdSvH8Kp https://t.co/tDGte3DmAc
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This study shows CCTA reveals increased inflammation in post-AMI patients, highlighting the need for refined risk assessment. #AHAJournals https://t.co/kGP2FYTnie https://t.co/jphO8sg5TG