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Mashup Score: 56
Molecular testing with gene expression profiling (GEP) and donor-derived cell-free DNA (dd-cfDNA) is increasingly used in the surveillance for acute cellular rejection (ACR) after heart transplant. However, the performance of dual testing over each test individually has not been established. Further, the impact of dual non-invasive surveillance on clinical decision-making has not been widely investigated.
Source: www.jhltonline.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 3Usage of older donors is associated with higher mortality after heart transplantation: A UNOS observational study - 14 hour(s) ago
Utilization of heart from older donors is variable across centers with uncertain outcomes of recipients. We sought to utilize a national registry to examine the usage and outcomes of heart transplant (HT) recipients from older donors. We also explored the impact of current donor heart allocation scheme on the outcomes of hearts from older donors.
Source: www.jhltonline.orgCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 42
Molecular testing with gene expression profiling (GEP) and donor-derived cell-free DNA (dd-cfDNA) is increasingly used in the surveillance for acute cellular rejection (ACR) after heart transplant. However, the performance of dual testing over each test individually has not been established. Further, the impact of dual non-invasive surveillance on clinical decision-making has not been widely investigated.
Source: www.jhltonline.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 29A radiographic score for human donor lungs on ex vivo lung perfusion predicts transplant outcomes - 3 day(s) ago
Ex vivo lung perfusion (EVLP) is an advanced platform for isolated lung assessment and treatment. Radiographs acquired during EVLP provide a unique opportunity to assess lung injury. The purpose of our study was to define and evaluate EVLP radiographic findings and their association with lung transplant outcomes.
Source: www.jhltonline.orgCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 5DQB1 antigen matching improves rejection-free survival in pediatric heart transplant recipients - 4 day(s) ago
Presence of donor-specific antibodies (DSAs), particularly to class II antigens, remains a major challenge in pediatric heart transplantation. Donor-recipient human leukocyte antigen (HLA) matching is a potential strategy to mitigate poor outcomes associated with DSAs. We evaluated the hypothesis that antigen mismatching at the DQB1 locus is associated with worse rejection-free survival.
Source: www.jhltonline.orgCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 16Cardiac magnetic resonance assessment of acute rejection and cardiac allograft vasculopathy in pediatric heart transplant - 6 day(s) ago
In pediatric heart transplant (PHT), cardiac catheterization with endomyocardial biopsy (EMB) is standard for diagnosing acute rejection (AR) and cardiac allograft vasculopathy (CAV) but is costly and invasive.
Source: www.jhltonline.orgCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 11Short-term outcomes after third-time lung transplantation: A single institution experience - 9 day(s) ago
Reoperative lung transplantation (LTx) survival has improved over time such that a growing number of patients may present for third-time LTx (L3Tx). To understand the safety of L3Tx, we evaluated perioperative outcomes and 3-year survival after L3Tx at a high-volume US LTx center.
Source: www.jhltonline.orgCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 8Recurrent Pulmonary Hypertension After Balloon Pulmonary Angioplasty for Inoperable Chronic Thromboembolic Pulmonary Hypertension - 10 day(s) ago
Balloon pulmonary angioplasty improves the hemodynamics of patients with inoperable chronic thromboembolic pulmonary hypertension; however, the clinical impact of recurrent pulmonary hypertension after balloon pulmonary angioplasty remains unclear.
Source: www.jhltonline.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 16Impact of center volume on outcomes after ventricular assist device implantation in pediatric patients: An analysis of the STS-Pedimacs database - 11 day(s) ago
To date, no pediatric studies have highlighted the impact of center’s ventricular assist device (VAD) volumes on post implant outcomes.
Source: www.jhltonline.orgCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 12
Cardiac metabolism is altered in heart failure and ischemia-reperfusion injury states. We hypothesized that metabolomic profiling during ex situ normothermic perfusion before heart transplantation (HT) would lend insight into myocardial substrate utilization and report on subclinical and clinical allograft dysfunction risk.
Source: www.jhltonline.orgCategories: General Medicine News, Cardiology News and JournTweet-
Metabolomic Profiling During Ex-situ Normothermic Perfusion Prior to Heart Transplantation Defines Patterns of Substrate Utilization & Correlates w Markers of Allograft Injury @laurentrubymd @_adevore @jacobniall @SvatiShah cc @ahajduczok @rachkataria 🔗: https://t.co/7jCkMAQpbf https://t.co/nOGrC0HVf4
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🚨1st SHORE pub‼️ > 2k🫀transplants, dual non-invasive rejection surveillance with GEP & dd-cfDNA: 1. ⬆️yield for ACR over either test alone 2. ⬇️number of biopsies 3. Great survival and🫀LVEF @KiranKhush1 @TheJHLT @ISHLT @AST_info @HFSA @NirUrielMD https://t.co/A5AXIs5wpC https://t.co/EUosZ0Nlwb