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Mashup Score: 18Beyond Code Status | NEJM - 2 hour(s) ago
Despite being absolutely clear that she wanted a quick, painless end of life, a geriatrician’s elderly mother receives aggressive care. How can we ensure that such patient preferences are honored?
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 68Welcoming the Era of Gene Editing in Medicine | NEJM - 2 hour(s) ago
Recent approvals of exa-cel for treatment of sickle cell disease and transfusion-dependent β-thalassemia mark the dawn of the era of gene editing in medicine. But ensuring access will be challenging.
Source: www.nejm.orgCategories: General Medicine News, Expert PicksTweet
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Mashup Score: 29
Exagamglogene autotemcel (exa-cel) is a nonviral cell therapy designed to reactivate fetal hemoglobin synthesis through ex vivo clustered regularly interspaced short palindromic repeats (CRISPR)–Ca…
Source: www.nejm.orgCategories: General Medicine News, General Journals & SocietTweet-
Of 35 patients with transfusion-dependent β-thalassemia treated with gene-edited autologous hematopoietic stem and progenitor cells, 32 had hemoglobin levels maintained without red-cell transfusions for at least 12 consecutive months. Full study results: https://t.co/LiTmJPoyfq https://t.co/KqsJLFrQJG
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Mashup Score: 68Welcoming the Era of Gene Editing in Medicine | NEJM - 3 hour(s) ago
Recent approvals of exa-cel for treatment of sickle cell disease and transfusion-dependent β-thalassemia mark the dawn of the era of gene editing in medicine. But ensuring access will be challenging.
Source: www.nejm.orgCategories: General Medicine News, Expert PicksTweet
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Mashup Score: 4Acute Promyelocytic Leukemia | NEJM - 4 hour(s) ago
A 47-year-old man presented with 2-day history of weakness and fever. Laboratory studies showed pancytopenia. A bone marrow biopsy showed promyelocytes with abundant intracellular rods.
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 25Nutritional Support for Moderate-to-Late–Preterm Infants — A Randomized Trial | NEJM - 13 hour(s) ago
Most moderate-to-late–preterm infants need nutritional support until they are feeding exclusively on their mother’s breast milk. Evidence to guide nutrition strategies for these infants is lacking….
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 12
Chimeric antigen receptor (CAR) T-cell therapies have revolutionized the treatment landscape for patients with relapsed or refractory B-cell lymphoid cancers.1 With studies showing that more than 5…
Source: www.nejm.orgCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 557Welcoming the Era of Gene Editing in Medicine | NEJM - 21 hour(s) ago
Recent approvals of exa-cel for treatment of sickle cell disease and transfusion-dependent β-thalassemia mark the dawn of the era of gene editing in medicine. But ensuring access will be challenging.
Source: www.nejm.orgCategories: General Medicine News, Expert PicksTweet
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Mashup Score: 21Drug-Induced Oxidative Hemolysis | NEJM - 23 hour(s) ago
A 57-year-old woman presented with a 3-day history of shortness of breath and dizziness. Laboratory studies showed severe anemia with hemolysis, along with cellular abnormalities in peripheral blood.
Source: www.nejm.orgCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 13Interview with Kevin Schulman on unionization as a response to consolidation and corporatization in health care. | NEJM - 24 hour(s) ago
Audio Interview from the New England Journal of Medicine — Interview with Kevin Schulman on unionization as a response to consolidation and corporatization in health care.
Source: www.nejm.orgCategories: General Medicine News, PulmonologyTweet
Superb and infuriating piece by @UCSF colleague (& great writer) @LouiseAronson about how her mom's clear, documented wish to avoid aggressive care at the end of life was ignored by a medical team locked into a we-did-this-so-we-must-do-that spiral. @NEJM https://t.co/o2qVZIjp4W https://t.co/Lmlxvu7z7w